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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1020</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANG OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Генерализованный туберкулезный процесс, длительное время протекавший под маской цирроза печени</article-title><trans-title-group xml:lang="en"><trans-title>Generalized tuberculosis with long-term course in the guise of liver cirrhosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лемешко</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lemeshko</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лемешко Зинаида Ароновна — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, главный научный сотрудник Научно-образовательного клинического центра инновационной терапии</p><p>119991, Москва,ул. Погодинская, д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Lemeshko Zinaida A — MD, PhD, professor, Chair of internal diseases propedeutics, medical faculty</p><p>119991, Moscow, Pogodinskaya street, 1, bld 1</p></bio><email xlink:type="simple">zinaidalemeshko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маевская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mayevskaya</surname><given-names>M. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихонов</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikhonov</surname><given-names>I. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мусина</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Musina</surname><given-names>N. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жаркова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zharkova</surname><given-names>M. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фоминых</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fominykh</surname><given-names>Ye. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивашкин</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivashkin</surname><given-names>V. T.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>18</day><month>07</month><year>2015</year></pub-date><volume>25</volume><issue>3</issue><fpage>85</fpage><lpage>89</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лемешко З.А., Маевская М.В., Тихонов И.Н., Мусина Н.П., Жаркова М.С., Фоминых Е.В., Ивашкин В.Т., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Лемешко З.А., Маевская М.В., Тихонов И.Н., Мусина Н.П., Жаркова М.С., Фоминых Е.В., Ивашкин В.Т.</copyright-holder><copyright-holder xml:lang="en">Lemeshko Z.A., Mayevskaya M.V., Tikhonov I.N., Musina N.P., Zharkova M.S., Fominykh Y.V., Ivashkin V.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1020">https://www.gastro-j.ru/jour/article/view/1020</self-uri><abstract><p>Цель исследования. Показать необычные клинические проявления и трудности диагностики распространенного туберкулезного процесса.Материал и методы. Обследована пациентка 25 лет, которая в течение 10 лет наблюдалась по поводу цирроза печени неуточненной этиологии. Проведен тщательный анализ клиники заболевания, данных объективного обследования, результатов лучевых и других методов диагностики.Результаты. Удалось заподозрить, а затем подтвердить наличие: диссеминированного туберкулеза с поражением легких, сердца, перикарда, плевры, мезентериальных лимфоузлов, печени; хронического туберкулезного плеврита справа с плевроциррозом; констриктивного перикардита с явлениями правожелудочковой недостаточности; кардиального фиброза печени (псевдоцирроза Пика); смешанной портальной гипертензии.Заключение. Подробный анализ клиники заболевания, объективных данных, а также использование комплекса визуальных и других методов исследования расширяют возможности диагностики диссеминированного туберкулезного процесса.</p></abstract><trans-abstract xml:lang="en"><sec><title>Aim of investigation</title><p>Aim of investigation. To demonstrate unusual clinical symptoms and difficulties of diagnostics of disseminated tuberculous process.</p></sec><sec><title>Material and methods</title><p>Material and methods. The 25 year-old patient, who was managed for 10 years for liver cirrhosis of nonspecified etiology, was investigated. The careful analysis of clinical presentation of disease, data of physical examination, results of radiological and other methods of diagnostics was carried out.</p></sec><sec><title>Results</title><p>Results. It was possible to suspect and subsequently to confirm disseminated tuberculosis with involvement of the lungs, the heart, pericardium, pleura, mesenteric lymph nodes, the liver; chronic right-sided tubercular pleurisy with pleurocirrhosis; constrictive pericarditis with signs of right ventricular failure; cardiac liver fibrosis (Pick's pseudocirrhosis); mixed portal hypertension.</p></sec><sec><title>Conclusion</title><p>Conclusion. The detailed analysis of clinical presentation of disease, physical data and application of complex of visual and other methods of investigation expand potential of diagnostics of disseminated tuberculous process.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез</kwd><kwd>цирроз печени</kwd><kwd>лучевые методы диагностики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tuberculosis</kwd><kwd>liver cirrhosis</kwd><kwd>radiological methods of diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Alimuddin Z., Raviglione M., Hafner R., C. Fordham von Reyn. Tuberculosis: review. Engl J Med 2013; 368:745-55.</mixed-citation><mixed-citation xml:lang="en">Alimuddin Z., Raviglione M., Hafner R., C. Fordham von Reyn. Tuberculosis: review. 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