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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1058</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANG OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Итоги длительного наблюдения больных хроническим гастритом после эрадикации инфекции H. pylori</article-title><trans-title-group xml:lang="en"><trans-title>Results of long-term follow-up of patients with chronic gastritis after H. pylori eradication</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лапина</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapina</surname><given-names>T. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лапина Татьяна Львовна – кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней </p><p>119991, Москва, ул. Погодинская, д. 1, стр. 1. </p></bio><bio xml:lang="en"><p>Lapina Tatyana L — MD, lecturer, Chair of internal diseases propedeutics, medical faculty</p><p>119991, Moscow, street Pogodinskaya, 1, bld. 1. </p></bio><email xlink:type="simple">lapinata@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тертычный</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tertychny</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насретдинова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasretdinova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Насретдинова Эльмира Равильевна – соискатель кафедры пропедевтики внутренних болезней лечебного факультета </p></bio><bio xml:lang="en"><p>Nasretdinova Elmira R — doctoral candidate, Chair of internal diseases propedeutics, medical faculty</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Картавенко</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kartavenko</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Картавенко Илона Михайловна – научный сотрудник НИО инновационной терапии </p></bio><bio xml:lang="en"><p>Kartavenko Ilona M — research associate, Scientific and educational clinical center of innovative therapy</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Параскевова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Paraskevova</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юрьева</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Yur’yeva</surname><given-names>Ye. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сторонова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Storonova</surname><given-names>O. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухманов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhmanov</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивашкин</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivashkin</surname><given-names>V. T.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow state medical university, Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>29</day><month>09</month><year>2015</year></pub-date><volume>25</volume><issue>4</issue><fpage>101</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лапина Т.Л., Тертычный А.С., Насретдинова Э.Р., Картавенко И.М., Параскевова А.В., Юрьева Е.Ю., Сторонова О.А., Трухманов А.С., Ивашкин В.Т., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Лапина Т.Л., Тертычный А.С., Насретдинова Э.Р., Картавенко И.М., Параскевова А.В., Юрьева Е.Ю., Сторонова О.А., Трухманов А.С., Ивашкин В.Т.</copyright-holder><copyright-holder xml:lang="en">Lapina T.L., Tertychny A.S., Nasretdinova E.R., Kartavenko I.M., Paraskevova A.V., Yur’yeva Y.Y., Storonova O.A., Trukhmanov A.S., Ivashkin V.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1058">https://www.gastro-j.ru/jour/article/view/1058</self-uri><abstract><p>Цель публикации. На примере клинических наблюдений проанализировать тактику длительного ведения больных хроническим гастритом после эрадикации инфекции H. pylori для профилактики рака желудка.Основные положения. Тактика ведения пациентов с хроническим гастритом после ликвидации H. pylori представлена на примере больных с различным риском развития рака желудка. Через полтора года после успешной эрадикационной терапии у женщины 57 лет подтверждена легкая атрофия и кишечная метаплазия антрального отдела без атрофии и кишечной метаплазии тела желудка. При отсутствии других факторов риска возникновения рака дальнейшее эндоскопическое наблюдение не требуется. Пятилетнее наблюдение за мужчиной 62 лет после успешной эрадикационной терапии продемонстрировало стабильную морфологическую картину без прогрессирования предраковых изменений. Учитывая выраженную атрофию и кишечную метаплазию антрального отдела и легкую атрофию тела желудка, а также отягощенный семейный анамнез пациенту показано ежегодное выполнение эзофагогастроскопии с биопсией.Заключение. Прогноз и тактика ведения больных хроническим гастритом после эрадикации инфекции H. pylori определяются в зависимости от выраженности атрофии и кишечной метаплазии антрального отдела и тела желудка, а также другими факторами риска развития рака, например отягощенным семейным анамнезом.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of publication</title><p>The aim of publication. To analyze approach for long-term management of patients with chronic gastritis after H. pylori eradication for stomach cancer prevention by the example of clinical cases.</p></sec><sec><title>Key points</title><p>Key points. The management approach of patients with chronic gastritis after eradication of H. pylori is presented by the example of patients with various risk of development of stomach cancer. In one and half year after successful eradication therapy in 57 year-old female patient mild atrophy and intestinal metaplasia of antrum without atrophy and intestinal metaplasia of corpus of the stomach was confirmed. At absence of other risk factors for cancer development further endoscopic follow-up is not required. Monitoring of 62 year-old male patient after successful eradication for 5 years has shown stable morphological pattern without progression of premalignant lesions. Taking into account both severe atrophy and intestinal metaplasia of antral region and mild atrophy of body of the stomach, as well as positive family history, esophagogastroscopy with biopsy is recommended once per year to this patient.</p></sec><sec><title>Conclusion</title><p>Conclusion. Prognosis and management approach of patients after eradication of H. pylori infection are determined by chronic gastritis in relation to severity of atrophy and intestinal metaplasia of antral region and corpus of the stomach, along with other risk factors for cancer development e.g. positive family history.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический гастрит</kwd><kwd>H. pylori</kwd><kwd>атрофия</kwd><kwd>кишечная метаплазия</kwd><kwd>эрадикационная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic gastritis</kwd><kwd>H. pylori</kwd><kwd>atrophy</kwd><kwd>intestinal metaplasia</kwd><kwd>eradication therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Correa P., Blanca Piazuelo M. The gastric precancerous cascade. J Clin Exp Pathol 2013; 3:147.</mixed-citation><mixed-citation xml:lang="en">Correa P., Blanca Piazuelo M. 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