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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1070</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ РАЗБОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL ANALYSIS</subject></subj-group></article-categories><title-group><article-title>Клиническое наблюдение: пациент 58 лет с резким похуданием, желтухой и кожным зудом</article-title><trans-title-group xml:lang="en"><trans-title>Fifty eight-year old-patient with acute weight loss, jaundice and pruritis (clinical case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваленко</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalenko</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коваленко Анна Сергеевна—клинический интерн кафедры пропедевтики внутренних болезней</p><p>119991, Москва, ул. Погодинская, д.1, стр. 1. </p></bio><bio xml:lang="en"><p>Kovalenko Anna S. — resident of the chair of internal diseases propedeutics</p><p>119991, Moscow, Pogodinskaya street, 1, bld 1. </p></bio><email xlink:type="simple">akovalenko@mcmedok.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулина</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulina</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шептулина Анна Фароковна—аспирант кафедры пропедевтики внутренних болезней</p></bio><bio xml:lang="en"><p>Sheptulina Anna F. — MD fellow, Chair of internal diseases propedeutics</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивашкин</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivashkin</surname><given-names>V. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивашкин Владимир Трофимович—доктор медицинских наук, профессор, академик РАН, заведующий кафедрой пропедевтики внутренних болезней </p></bio><bio xml:lang="en"><p>Ivashkin Vladimir T. — MD, PhD, professor, academician of the Russian Academy of Science, head of the chair of internal diseases propedeutics, medical faculty</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>10</month><year>2015</year></pub-date><volume>25</volume><issue>5</issue><fpage>64</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коваленко А.С., Шептулина А.Ф., Ивашкин В.Т., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Коваленко А.С., Шептулина А.Ф., Ивашкин В.Т.</copyright-holder><copyright-holder xml:lang="en">Kovalenko A.S., Sheptulina A.F., Ivashkin V.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1070">https://www.gastro-j.ru/jour/article/view/1070</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Davern T.J. 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