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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1074</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАЦИОНАЛЬНАЯ ШКОЛА ГАСТРОЭНТЕРОЛОГОВ, ГЕПАТОЛОГОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NATIONAL COLLEGE OF GASTROENTEROLOGISTS, HEPATOLOGISTS</subject></subj-group></article-categories><title-group><article-title>Эффективность применения растительного препарата STW 5 в многоцелевой терапии функциональной диспепсии</article-title><trans-title-group xml:lang="en"><trans-title>Efficacy of the herbal preparation STW 5 in multi-target therapy of functional dyspepsia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шептулин Аркадий Александрович – доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней лечебного факультета </p></bio><bio xml:lang="en"><p>Sheptulin Arkady A. — MD, PhD, professor, chair of internal diseases propedeutics, medical faculty</p><p>119991, Moscow, Pogodinskaya street, 1, bld 1</p></bio><email xlink:type="simple">arkalshep@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кайбышева</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaybysheva</surname><given-names>V. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кайбышева Валерия Олеговна – кандидат медицинских наук, ассистент кафедры пропедевтики внутренних болезней лечебного факультета </p></bio><bio xml:lang="en"><p>Kaybysheva Valeriya O. — MD, assistant-professor, chair of internal diseases propedeutics, medical faculty</p><p>119991, Moscow, Pogodinskaya street, 1, bld 1</p></bio><email xlink:type="simple">valeriakai@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>10</month><year>2015</year></pub-date><volume>25</volume><issue>5</issue><fpage>101</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шептулин А.А., Кайбышева В.О., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Шептулин А.А., Кайбышева В.О.</copyright-holder><copyright-holder xml:lang="en">Sheptulin A.A., Kaybysheva V.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1074">https://www.gastro-j.ru/jour/article/view/1074</self-uri><abstract><p>Цель обзора. Рассмотреть механизмы действия и результаты клинического применения растительного препарата STW 5 (Иберогаста®) при лечении больных функциональной диспепсией (ФД).Основные положения. Иберогаст® представляет собой комбинированный препарат, компонентами которого служат экстракты 9 лекарственных растений. Механизм действия включает в себя влияние на моторику желудка и кишечника, висцеральную чувствительность, а также противовоспалительный и цитопротективный эффекты. Контролируемые клинические исследования подтвердили высокую эффективность Иберогаста® при лечении больных ФД (в том числе в педиатрической практике), а также хорошую переносимость препарата.Заключение. Результаты применения Иберогаста® позволяют считать его эффективным средством в многоцелевой терапии ФД.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of review</title><p>The aim of review. To discuss mechanisms of action and results of clinical application of plant-derived drug STW 5 (Iberogast®) for treatment of functional dyspepsia (FD).</p></sec><sec><title>Key points</title><p>Key points. Iberogast® is the combined agent containing extracts of 9 medicinal plants. Mechanism of action includes effect on motility of the stomach and intestine, visceral sensitivity along with anti-inflammatory and cytoprotective effects. Controlled clinical trials have confirmed high efficacy of Iberogast® at treatment of FD (including pediatric practice) as well as good tolerability of the drug.</p></sec><sec><title>Conclusion</title><p>Conclusion. Results of Iberogast® application allow to consider its as effective agent in multi-target therapy of FD.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональная диспепсия</kwd><kwd>STW 5 (Иберогаст®)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional dyspepsia</kwd><kwd>STW 5 (Iberogast®)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т., Шептулин А.А., Лапина Т.Л., Картавенко И.М. и др. 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