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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1123</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ И ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES AND REVIEWS</subject></subj-group></article-categories><title-group><article-title>Оптимизация диагностики гастроэзофагеальной рефлюксной болезни у детей</article-title><trans-title-group xml:lang="en"><trans-title>Improvement of gastroesophageal reflux disease diagnostics in pediatrics</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эрдес</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Erdes</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эрдес Светлана Ильинична — доктор медицинских наук, профессор, заведующая кафедрой пропедевтики детских болезней педиатрического факультета</p><p>119991, Москва, ул. Трубецкая, д. 8</p></bio><bio xml:lang="en"><p>Erdes Svetlana I — MD, PhD, professor, head of the chair of pediatric propedeutics, pediatric faculty</p><p>119991, Moscow, Trubetskaya street, 8</p></bio><email xlink:type="simple">erdes@mma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полищук</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Polischuk</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полищук Альбина Ринатовна — аспирант кафедры пропедевтики детских болезней педиатрического факультета  </p><p>119991, Москва, ул. Трубецкая, д. 8</p><p> </p></bio><bio xml:lang="en"><p>Polischuk Albina R — post-graduate student of chair of pediatric propedeutics, pediatric faculty</p><p>119991, Moscow, Trubetskaya street, 8</p></bio><email xlink:type="simple">ar.polischuk@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый Московский государственный медицинский университет им. И. М. Сеченова»  Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university», Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>19</day><month>04</month><year>2024</year></pub-date><volume>24</volume><issue>4</issue><fpage>4</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Эрдес С.И., Полищук А.Р., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Эрдес С.И., Полищук А.Р.</copyright-holder><copyright-holder xml:lang="en">Erdes S.I., Polischuk A.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1123">https://www.gastro-j.ru/jour/article/view/1123</self-uri><abstract><p>Цель обзора. Представить данные зарубежных клинических исследований, посвященных оптимизации диагностики гастроэзофагеальной рефлюксной болезни (ГЭРБ) у детей.Основные положения. ГЭРБ — частая проблема в педиатрии, ее проявления иногда трудно диагностировать. В основном гастроэзофагеальный рефлюкс (ГЭР) является физиологическим и встречается у каждого ребенка, особенно после еды. Многие эпизоды рефлюксов протекают бессимптомно, однако у некоторых детей ГЭР связан с различными серьезными симптомами и деструкцией слизистой оболочки пищевода, так как защитные механизмы в детском возрасте еще недостаточно развиты. Поэтому необходимы дополнительные исследования, чтобы дифференцировать пищеводные и внепищеводные проявления ГЭРБ. Одним из современных методов является многоканальная внутрипросветная импеданс-pH-метрия. Это очень чувствительный метод, позволяющий обнаружить некислые, слабокислые рефлюксы, высоту распространения рефлюкса.Заключение. Многоканальная внутрипросветная импедансометрия по сравнению с внутрипищеводной рН-метрией имеет более широкие диагностические возможности, поскольку позволяет определять эпизоды кислого, некислого и щелочного рефлюксов.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of review</title><p>The aim of review. To present data of the foreign clinical studies devoted to optimization of diagnostics of gastroesophageal reflux disease (GERD) in children.</p></sec><sec><title>Key points</title><p>Key points. GERD is a frequent issue in pediatrics, its manifestations are difficult to reveal sometimes. In most of the cases gastroesophageal reflux (GER) is physiological, especially postprandially and can be detected in every child. Many episodes of refluxes proceed asymptomatically, however in some children GER is related to various serious symptoms and damage of esophageal mucosa because protective mechanisms are insufficiently developed in the young age. Therefore additional investigations are required to differentiate esophageal and extraesophageal manifestations of GERD. Multichannel intraluminal impedance — pH-metry is one of the modern diagnostic methods. It is very sensitive, allowing to reveal non-acidic, weakly acidic refluxes, as well as the height of refluxate spread.</p></sec><sec><title>Conclusion</title><p>Conclusion. Multichannel intraluminal impedance measurement in comparison with intraesophageal pH-metry has wider diagnostic potentials as allows to determine episodes of acidic, non-acidic and alkaline refluxes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гастроэзофагеальная рефлюксная болезнь</kwd><kwd>дети</kwd><kwd>pH-импедансометрия пищевода</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastroesophageal reflux disease</kwd><kwd>children</kwd><kwd>pH-impedance measurement of the esophagus</kwd><kwd>diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Стандарты диагностики и лечения кислотозависимых и ассоциированных с Helicobacter pylori заболеваний (четвертое Московское соглашение). 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