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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1124</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГЕПАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEPATOLOGY</subject></subj-group></article-categories><title-group><article-title>Современное состояние проблемы диагностики гепатоцеллюлярного рака</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostics of hepatocellular cancer: state-of-the-art</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данзанова</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Danzanova</surname><given-names>T. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Данзанова Татьяна Юрьевна – кандидат медицинских наук, старший научный сотрудник, отделение ультразвуковой диагностики отдела лучевой диагностики и интервенционной радиологии</p><p>115478, Москва, Каширское шоссе, д. 24</p></bio><bio xml:lang="en"><p>Danzanova Tatyana Yu — MD, senior research associate, department of ultrasound diagnostics, department of radiology and intervention radiology</p><p>115478, Moscow, Kashirskoe highway, 24</p></bio><email xlink:type="simple">danzanova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синюкова</surname><given-names>Г. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinyukova</surname><given-names>G. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синюкова Галина Тимофеевна – доктор медицинских наук, профессор, заведующая, отделение ультразвуковой диагностики отдела лучевой диагностики и интервенционной радиологии</p></bio><bio xml:lang="en"><p>Sinyukova Galina T — MD, PhD, professor, head of department of ultrasound diagnostics, department of radiology and intervention radiology</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лепэдату</surname><given-names>П. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lepedatu</surname><given-names>P. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лепэдату Павел Иванович – кандидат медицинских наук, старший научный сотрудник, отделение ультразвуковой диагностики отдела лучевой диагностики и интервенционной радиологии</p></bio><bio xml:lang="en"><p>Lepedatu Paul I — MD, senior research associate, department of ultrasound diagnostics, department of radiology and intervention radiology</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ клинической онкологии ФГБУ «РОНЦ им. Н.Н. Блохина» РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Blokhin Cancer Research Center, Russian Academy of Medical Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>19</day><month>04</month><year>2024</year></pub-date><volume>24</volume><issue>4</issue><fpage>12</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Данзанова Т.Ю., Синюкова Г.Т., Лепэдату П.И., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Данзанова Т.Ю., Синюкова Г.Т., Лепэдату П.И.</copyright-holder><copyright-holder xml:lang="en">Danzanova T.Y., Sinyukova G.T., Lepedatu P.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1124">https://www.gastro-j.ru/jour/article/view/1124</self-uri><abstract><p>Цель обзора. Представить особенности диагностики гепатоцеллюлярного рака (ГЦР).Основные положения. Рассмотрены факторы развития ГЦР, принципы проведения скрининга в группе риска. Описана роль ультразвукового исследования, рентгеновской, компьютерной и магнитно-резонансной томографии в диагностике ГЦР, а также отражены дополнительные сведения, которые можно получить с помощью лучевых методов исследования, что имеет огромное значение в определении резектабельности и предоперационном планировании хирургического вмешательства. Описана лучевая диагностика при сопутствующем циррозе, сложность обнаружения ГЦР малых размеров. Лучевую дифференциальную диагностику ГЦР следует проводить с диспластическими узелками. Рассмотрены преимущества и ограничения каждого из методов визуализации.Заключение. Проблема диагностики гепатоцеллюлярного рака продолжает оставаться актуальной и требует проведения дальнейших исследований.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of review</title><p>The aim of review. To present features of hepatocellular carcinoma (HCC) diagnostics.</p></sec><sec><title>Key points</title><p>Key points. Factors of HCC development, principles of screening diagnostics in risk group are discussed. The role of ultrasound investigation, X-ray, computer and magnetic-resonance tomography in HCC diagnostics is described, and also additional data which can be received with by radiological diagnostic methods that has high value in assessment resectability and preoperative surgical planning are reflected. The radiology is described at accompanying cirrhosis, difficulty of small HCC detection. Radiological differential diagnostics of HCC should be carried out with dysplastic nodules. Advantages and restrictions of each of method of visualization are presented.</p></sec><sec><title>Conclusion</title><p>Conclusion. The issue of hepatocellular cancer diagnostics remains actual and requires further studies.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гепатоцеллюлярный рак</kwd><kwd>ультразвуковое исследование</kwd><kwd>рентгеновская компьютерная томография</kwd><kwd>магнитно-резонансная томография</kwd><kwd>позитронно-эмиссионная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hepatocellular cancer</kwd><kwd>ultrasound investigation</kwd><kwd>x-ray computer tomography</kwd><kwd>magneticresonance tomography</kwd><kwd>positron-emission tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шерлок Ш., Дули Дж. Заболевания печени и желчных путей. М.: ГЭОТАР; 1999:75-7, 603-733.</mixed-citation><mixed-citation xml:lang="en">Шерлок Ш., Дули Дж. Заболевания печени и желчных путей. 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