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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2024-34-2-101-131</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1222</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GUIDELINES</subject></subj-group></article-categories><title-group><article-title>Диагностика и лечение язвенной болезни у взрослых (Клинические рекомендации Российской гастроэнтерологической ассоциации, Российского общества колоректальных хирургов, Российского эндоскопического общества и Научного сообщества по содействию клиническому изучению микробиома человека)</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostics and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, the Russian Society of Colorectal Surgeons, the Russian Endoscopic Society and the Scientific Society for the Clinical Study of Human Microbiome)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6815-6015</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивашкин</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivashkin</surname><given-names>V. Т.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивашкин Владимир Трофимович — доктор медицинских наук, профессор, академик РАН, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологиии  гепатологии</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Vladimir T. Ivashkin — Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Head of the Department of Propaedeutics of Internal Disease, Gastroenterologyand  Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">ivashkin_v_t@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6114-564X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mayev</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маев Игорь Вениаминович — доктор медицинских наук, профессор, академик РАН, заведующий кафедрой пропедевтики внутренних болезней и гастроэнтерологии</p><p>127473, г. Москва, ул. Делегатская, 20, стр. 1</p></bio><bio xml:lang="en"><p>Igor V. Maev — Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Medical Sciences, Head of the Department of Propaedeutics of Internal Diseases and Gastroenterology</p><p>127473, Moscow, Delegatskaya str., 20, build. 1</p></bio><email xlink:type="simple">igormaev@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7134-6821</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Царьков</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsarkov</surname><given-names>Р. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Царьков Петр Владимирович — доктор медицинских наук, профессор, заведующий кафедрой хирургии</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Petr V. Tsarkov — Dr. Sci. (Med.), Professor, Head of  the Department of Surgery</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">tsarkov@kkmx.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5061-0139</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королев</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolev</surname><given-names>М. Р.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Королев Михаил Павлович — доктор медицинских наук, заведующий кафедрой общей хирургии с курсом эндоскопии</p><p>119014, г. Санкт-Петербург, Литейный проспект, 56</p></bio><bio xml:lang="en"><p>Mikhail P. Korolev — Dr. Sci. (Med.), Head of the Departament of General Surgery with an Endoscopy Course</p><p>119014, St. Petersburg, Liteiny ave., 56</p></bio><email xlink:type="simple">korolevmp@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4007-7112</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреев</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreev</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андреев Дмитрий Николаевич — кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней и гастроэнтерологии</p><p>127473, г. Москва, ул. Делегатская, 20, стр. 1</p></bio><bio xml:lang="en"><p>Dmitry N. Andreev – Cand. Sci. (Med.), Associate Professor at the Department of Propaedeutics of Internal Diseases and Gastro-enterology</p><p>127473, Moscow, Delegatskaya str., 20, build. 1</p></bio><email xlink:type="simple">dna-mit8@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9971-8295</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранская</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranskaya</surname><given-names>Е. К.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баранская Елена Константиновна — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней лечебного факультета</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Elena K. Baranskaya — Dr. Sci. (Med.), Professor of the Department of Propaedeutics of Internal Diseases</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">ebaranskaya@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бордин</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bordin</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бордин Дмитрий Станиславович — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней и гастроэнтерологии; заведующий отделом патологии поджелудочной железы, желчных путей и верхних отделов пищеварительного тракта; профессор кафедры общей врачебной практики и семейной медицины ФПДО</p><p>111123, г. Москва, шоссе Энтузиастов, 86, стр. 6</p></bio><bio xml:lang="en"><p>Dmitry S. Bordin — Dr. Sci. (Med.), Professor of the Department of Internal Medicine Propaedeutics and Gastroenterology; Head of the Department of Pancreatic, Bile andUpper Gastrointestinal Pathology; Professor of the Department of GeneralMedical Practice and Family Medicine</p><p>111123, Moscow, Entuziastov highway, 86, build. 6</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурков</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Burkov</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурков Сергей Геннадьевич — доктор медицинских наук, профессор, заместитель главного врача</p><p>119090, г. Москва, Грохольский пер., 31</p></bio><bio xml:lang="en"><p>Sergey G. Bourkov — Dr. Sci. (Med.), Professor, Deputy Chief Physician</p><p>119090, Moscow, Grokholsky lane, 31</p></bio><email xlink:type="simple">bourk@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9449-5945</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Деринов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Derinov</surname><given-names>А. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Деринов Александр Александрович — кандидат медицинских наук, доцент кафедры хирургии Института клинической медицины</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Alexander A. Derinov — Cand. Sci. (Med.), Associate Professor at the Department of Surgery, Institute of Clinical Medicine</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">alexandr.derinov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0283-2217</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефетов</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Efetov</surname><given-names>S. К.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефетов Сергей Константинович — кандидат медицинских наук, доцент кафедры хирургии Института клинической медицины им. Н.В. Склифосовского, заведующий хирургическим отделением № 2 Университетской клинической больницы № 4</p><p>119435, г. Москва, ул. Большая Пироговская, 2–4</p></bio><bio xml:lang="en"><p>Sergey K. Efetov — Cand. Sci. (Med.), Associate Professor at the Department of Surgery, Institute of Clinical Medicine named after. N.V. Sklifosovsky, Head of Surgical DepartmentNo. 2, University Clinical Hospital No. 4</p><p>119435, Moscow, Bolshaya Pirogovskaya str., 2–4</p></bio><email xlink:type="simple">efetov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4456-8725</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лапина</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapina</surname><given-names>Т. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лапина Татьяна Львовна — кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней гастроэнтерологии, гепатологии</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p><p> </p></bio><bio xml:lang="en"><p>Tatiana L. Lapina — Cand. Sci. (Med.), Associate Professor at the Department of Propaedeutics of Internal Diseases</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">lapina_t_l@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4391-5441</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlov</surname><given-names>Р. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлов Павел Владимирович — кандидат медицинских наук, заведующий отделением диагностической и лечебной эндоскопии Университетской клинической больницы № 2</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Pavel V. Pavlov — Cand. Sci. (Med.), Head of the Department of Diagnostic and Therapeutic Endoscopy, University Clinical Hospital No. 2</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">pvpavlov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8101-2155</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пирогов</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pirogov</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пирогов Сергей Сергеевич — доктор медицинских наук, заведующий отделом эндоскопии</p><p>125284, г. Москва, 2-й Боткинский пр., 3</p></bio><bio xml:lang="en"><p>Sergey S. Pirogov — Dr. Sci. (Med.), Dr. Sci. (Med.), Head of the Department of Endoscopy</p><p>125284, Moscow, 2st Botkinsky lane, 3</p></bio><email xlink:type="simple">pirogov@mail.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1312-120X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полуэктова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Poluektova</surname><given-names>Е. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полуэктова Елена Александровна — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Elena A. Poluektova — Dr. Sci. (Med.), Professor at the Department of  InternalDiseasePropaedeutics, Gastroenterology and Hepatology</p><p>119991, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">poluektova_e_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5554-7084</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkachev</surname><given-names>А. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ткачев Александр Васильевич — доктор медицинских наук, профессор, заведующий кафедрой пропедевтики внутренних болезней</p><p>344022, г. Ростов-на-Дону, Нахичеванский пер., 29</p></bio><bio xml:lang="en"><p>Alexander V. Tkachev — Dr. Sci. (Med.), Professor, Head of  the Department of Propaedeutics of Internal Diseases</p><p>344022, Rostov-on-Don, Nakhichevansky lane, 29</p></bio><email xlink:type="simple">tkachev@aaanet.ru</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3362-2968</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухманов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhmanov</surname><given-names>А. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трухманов Александр Сергеевич — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии Института клинической медицины им. Н.В. Склифосовского</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Alexander S. Trukhmanov — Dr. Sci. (Med.), Professor at  the Department of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology</p><p>119991, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">alexander.trukhmanov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5506-5555</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ульянин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Uljanin</surname><given-names>А. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульянин Анатолий Игоревич — врач-гастроэнтеролог отделения хронических заболеваний кишечника и поджелудочной железы клиники пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х. Василенко</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Anatoly I. Ulyanin — Gastroenterologist, Department of Chronic Intestinal and Pancreatic Diseases, V.Kh. Vasilenko Clinic of Propaedeutics of Internal Disease, Gastroenterologyand Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">ulyanin_a_i@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6036-7061</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>Е. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федоров Евгений Дмитриевич — доктор медицинских наук, профессор, главный научный сотрудник научно-исследовательской лаборатории хирургической гастроэнтерологии и  эндоскопии; клинический руководитель отделения эндоскопической хирургии</p><p>117997, г. Москва, ул. Островитянова, 1</p><p> </p></bio><bio xml:lang="en"><p>Evgeny D. Fedorov — Dr. Sci. (Med.), Professor, Chief Researcher, Research Laboratory of Surgical Gastroenterology and Endoscopy; Clinical Head of the Departmentof Endoscopic Surgery</p><p>117997, Moscow, Ostrovityanova str., 1</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1395-9566</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulin</surname><given-names>А. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шептулин Аркадий Александрович — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии</p><p>119435, г. Москва, ул. Погодинская, 1, стр. 1</p></bio><bio xml:lang="en"><p>Arkady A. Sheptulin — Dr. Sci. (Med.), Professor at the Department of Propaedeutics of Internal Diseases, Gastroenterology and  Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, build. 1</p></bio><email xlink:type="simple">arkalshep@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации; ГБУЗ «Московский клинический научный центр им. А.С. Логинова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry; A.S. Loginov Moscow Clinical Science Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБУ «Поликлиника № 3» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polyclinic No. 3 of Presidential Administration of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Московский научно-исследовательский онкологический институт им. П.А. Герцена — филиал ФГБУ «Национальный медицинский исследовательский радиологический центр» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>P.A. Hertsen Moscow Oncology Research Center — Branch of “National Medical Research Radiological Center”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>ФГБУ ВО «Ростовский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>ФГБУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>21</day><month>05</month><year>2024</year></pub-date><volume>34</volume><issue>2</issue><fpage>101</fpage><lpage>131</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ивашкин В.Т., Маев И.В., Царьков П.В., Королев М.П., Андреев Д.Н., Баранская Е.К., Бордин Д.С., Бурков С.Г., Деринов А.А., Ефетов С.К., Лапина Т.Л., Павлов П.В., Пирогов С.С., Полуэктова Е.А., Ткачев А.В., Трухманов А.С., Ульянин А.И., Федоров Е.Д., Шептулин А.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ивашкин В.Т., Маев И.В., Царьков П.В., Королев М.П., Андреев Д.Н., Баранская Е.К., Бордин Д.С., Бурков С.Г., Деринов А.А., Ефетов С.К., Лапина Т.Л., Павлов П.В., Пирогов С.С., Полуэктова Е.А., Ткачев А.В., Трухманов А.С., Ульянин А.И., Федоров Е.Д., Шептулин А.А.</copyright-holder><copyright-holder xml:lang="en">Ivashkin V.Т., Mayev I.V., Tsarkov Р.V., Korolev М.Р., Andreev D.N., Baranskaya Е.К., Bordin D.S., Burkov S.G., Derinov А.А., Efetov S.К., Lapina Т.L., Pavlov Р.V., Pirogov S.S., Poluektova Е.А., Tkachev А.V., Trukhmanov А.S., Uljanin А.I., Fedorov Е.D., Sheptulin А.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1222">https://www.gastro-j.ru/jour/article/view/1222</self-uri><abstract><sec><title>Цель</title><p>Цель. В клинических рекомендациях, предназначенных для врачей-гастроэнтерологов, врачей общей практики (семейных врачей), врачей-терапевтов, хирургов, эндоскопистов, изложены современные методы диагностики и лечения язвенной болезни.</p></sec><sec><title>Основное содержание</title><p>Основное содержание. Клинические рекомендации содержат современные представления об этиологии и патогенезе язвенной болезни, ее клинических особенностях, методах лабораторной и инструментальной диагностики, основных подходах к консервативному и хирургическому лечению. В них приводятся критерии оценки качества оказания медицинской помощи, алгоритм действий врача, а также информация для пациента.</p></sec><sec><title>Заключение</title><p>Заключение. Знание врачами современных методов диагностики и терапии язвенной болезни будет способствовать улучшению результатов ее лечения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. The guidelines set out the modern methods of diagnostics and treatment of peptic ulcer and are created for gastroenterologists, primary care physicians, general practitioners, surgeons, endoscopists.</p></sec><sec><title>Key points</title><p>Key points. The clinical guidelines contain modern views on the etiology and pathogenesis of peptic ulcer, its clinical features, methods of laboratory and instrumental diagnostics, the main approaches to conservative and surgical treatment. They include the criteria for assessment of the quality of medical care, the algorithm of the doctor's actions, as well as information for the patient.</p></sec><sec><title>Conclusion</title><p>Conclusion. Knowledge of modern methods of diagnostics and therapy of peptic ulcers will contribute to improving the results of its treatment.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>язвенная болезнь</kwd><kwd>этиология</kwd><kwd>патогенез</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>peptic ulcer</kwd><kwd>etiology</kwd><kwd>pathogenesis</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shay H., Sun D.C.H. Etiology and pathology of gastric and duodenal ulcer. In: Bockus H.L. Gastroenterology. Philadelphia-London: Saunders Elsevier. 1968:420–65.</mixed-citation><mixed-citation xml:lang="en">Shay H., Sun D.C.H. Etiology and pathology of gastric and duodenal ulcer. In: Bockus H.L. Gastroenterology. 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