gastro-jРоссийский журнал гастроэнтерологии, гепатологии, колопроктологииRussian Journal of Gastroenterology, Hepatology, Coloproctology1382-43762658-6673«Gastro» LLCgastro-j-1265Research ArticleНАЦИОНАЛЬНАЯ ШКОЛА ГАСТРОЭНТЕРОЛОГОВ, ГЕПАТОЛОГОВNATIONAL COLLEGE OF GASTROENTEROLOGISTS, HEPATOLOGISTSЭозинофильный эзофагит: обзор литературы и описание собственного наблюденияEosinophilic esophagitis: literature review and original case presentationИвашкинВ. Т.IvashkinV. T.БаранскаяЕ. К.BaranskayaYe. K.КайбышеваВ. О.KaybyshevaV. O.ИвановаЕ. В.IvanovaYe. V.ФедоровЕ. Д.FedorovYe. D.ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» РосздраваРоссияРГМУ им. Н.И. ПироговаРоссия2012100220122217181Copyright © Ивашкин В.Т., Баранская Е.К., Кайбышева В.О., Иванова Е.В., Федоров Е.Д., 20122012Ивашкин В.Т., Баранская Е.К., Кайбышева В.О., Иванова Е.В., Федоров Е.Д.Ivashkin V.T., Baranskaya Y.K., Kaybysheva V.O., Ivanova Y.V., Fedorov Y.D.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gastro-j.ru/jour/article/view/1265

Цель публикации. На примере собственного наблюдения продемонстрировать особенности клинической картины, сложности диагностики и лечения эозинофильного эзофагита.Особенности клинического наблюдения. У молодого пациента диагноз эозинофильного эзофагита был установлен спустя 20 лет после манифестации заболевания на стадии развившихся осложнений (стриктура пищевода). Консервативное лечение топическими кортикостероидами не привело к разрешению дисфагии и морфологических изменений стенки пищевода, в связи с чем больному было рекомендовано проведение курса системных кортикостероидов с дальнейшим решением вопроса о дилатации пищевода. Недостаточная информированность врачей-интернистов и эндоскопистов о данной патологии часто приводит к установлению неверных диагнозов, поздней диагностике, развитию осложнений, требующих хирургических вмешательств, снижению качества жизни больных.Заключение. Эоэинофильный эзофагит – это хроническое иммуно-антигенопосредованное воспалительное заболевание пищевода с еще недостаточно изученным этиопатогенезом. Диагностика основана на характерной клинической картине дисфагии в обязательной совокупности с выявлением эозинофильной инфильтрации слизистой оболочки пищевода при гистологическом исследовании. Возможности лечения эозинофильного эзофагита в настоящее время невелики и включают соблюдение строгой элиминационной диеты и применение стероидных гормонов.

The aim of publication

The aim of publication. To show features of clinical pattern, difficulties of diagnostics and treatment of eosinophilic esophagitis at the example of clinical case.

Features of clinical case. In young patient the diagnosis of eosinophilic esophagitis at stage of complications (esophageal stricture) has been made 20 years after manifestation of disease. Conservative treatment by topical corticosteroids did not result in resolution of dysphagia and morphological changes of esophageal wall that required a course of systemic corticosteroids with further dilatation of the esophagus recommended to the patient. Poor knowledge of this disease by internists and endoscopists often results in establishment of incorrect diagnoses, late diagnostics, development of complications requiring surgical interventions, decrease of quality of life of patients.

Conclusion

Conclusion. Eosinophilic esophagitis is chronic immune antigen-mediated inflammatory disease of the esophagus with still obscure etiopathogenesis. Diagnostics is based on characteristic clinical pattern of dysphagia that is always combined to eosinophilic infiltration of esophageal mucosa at histological study. Treatment options of eosinophilic esophagitis are limited now and include strict eliminative diet and application of steroid hormones.

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The authors declare that there are no conflicts of interest present.