gastro-j

Российский журнал гастроэнтерологии, гепатологии, колопроктологии

Russian Journal of Gastroenterology, Hepatology, Coloproctology

1382-43762658-6673

«Gastro» LLC

gastro-j-1275

Research Article

ГЕПАТОЛОГИЯ

HEPATOLOGY

Методы прогнозирования риска и мониторинг эффективности терапии кровотечений из варикозно-расширенных вен пищевода у больных циррозом печени

Methods of risk prediction and monitoring of treatment response rate of bleedings from esophageal varices in patients with liver cirrhosis

Гарбузенко

Д. В.

Garbuzenko

D. V.

Челябинская государственная медицинская академияРоссияChelyabinsk State Medical AcademyRussian Federation

2012

17042012

2223644

2012

Гарбузенко Д.В.

Garbuzenko D.V.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.gastro-j.ru/jour/article/view/1275

Цель обзора. Описать методы прогнозирования риска кровотечений из варикозно-расширенных вен пищевода (ВРВП) у больных циррозом печени и показать роль некоторых из них в мониторинге эффективности терапии этого осложнения.Основные положения. Фиброгастродуоденоскопия и измерение градиента печеночного венозного давления в настоящее время остаются общепринятыми методами скрининга больных циррозом печени для определения риска развития кровотечений из ВРВП. Присущие им недостатки способствовали изучению чувствительности и специфичности других предикторов этого осложнения, а также технологий, оценивающих тяжесть портальной гипертензии, таких как капсульная эндоскопия, допплеросонография, мультиспиральная компьютерная томография, неинвазивные способы диагностики фиброза печени и ряда других.Заключение. Оптимизация известных методов оценки портальной гипертензии, а также разработка новых, основанных на патофизиологических механизмах ее развития, позволит повысить эффективность мероприятий, направленных на профилактику кровотечений из ВРВП у больных циррозом печени.

The aim of review

The aim of review. To describe methods of bleeding from varicose esophageal veins (VEV) risk estimation in patients with liver cirrhosis and to demonstrate a role of some of them in monitoring of treatment response rate.

Original positions

Original positions. Gastroduodenoscopy and hepatic venous pressure gradient measurement remain to be the standard methods of screening diagnostics of patients with liver cirrhosis for estimation of VEV bleeding risk nowadays. Their inherent disadvantages promoted studying of sensitivity and specificity of other predictors of this complication, as well as technologies estimating severity of portal hypertension, such as capsule endoscopy, Doppler ultrasound, multispiral computer tomography, non-invasive methods of liver fibrosis diagnostics and of some others.

Conclusion

Conclusion. Optimization of known methods of assessment of portal hypertension, and development of new, pathophysiologically based methods, allows to increase efficacy of VEV bleedings prophylaxis in patients with liver cirrhosis.

цирроз печенипортальная гипертензиякровотечения из варикозно-расширенных вен пищеводапрогнозирование риска

liver cirrhosisportal hypertensionbleedings from varicose esophageal veinsrisk prediction

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The authors declare that there are no conflicts of interest present.