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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2024-34-6-94-99</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1356</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Cолидно-псевдопапиллярная опухоль поджелудочной железы (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Case of Solid Pseudopapillary Neoplasm of Pancreas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-0572-8713</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамзачелебиоглу</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Hamzaçelebioğlu</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мерве Хамзачелебиоглу — хирург отделения общей хирургии</p><p>35170, г. Измир, Карабаглар, ул. Саим Чикрыкчи, 59 </p></bio><bio xml:lang="en"><p>Merve Hamzaзelebioğlu — M.D., Surgeon at the Department of General Surgery, Izmir Bozyaka Training and Research Hospital, Izmir Faculty of Medicine 35170, Izmir, Karabağlar, Saim Çıkrıkçı str., 59</p></bio><email xlink:type="simple">mervehamzacelebioglu@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7820-9088</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Урейн</surname><given-names>О.</given-names></name><name name-style="western" xml:lang="en"><surname>Üreyen</surname><given-names>O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орхан Урейн — врач, доцент, отделение общей хирургии </p><p>35170, г. Измир, Карабаглар, ул. Саим Чикрыкчи, 59 </p></bio><bio xml:lang="en"><p>Orhan Üreyen — M.D., Associate Professor, Department of General Surgery, Izmir Bozyaka Training and Research Hospital, Izmir Faculty of Medicine</p><p>35170, Izmir, Karabağlar, Saim Çıkrıkçı str., 59 </p></bio><email xlink:type="simple">mervehamzacelebioglu@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7406-0610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргон</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Argon</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Асуман Аргон — врач, профессор, отделение общей хирургии </p><p>35170, г. Измир, Карабаглар, ул. Саим Чикрыкчи, 59 </p></bio><bio xml:lang="en"><p>Asuman Argon — M.D., Professor, Department of General Surgery, Izmir Bozyaka Training and Research Hospital, Izmir Faculty of Medicine </p><p>35170, Izmir, Karabağlar, Saim Çıkrıkçı str., 59 </p></bio><email xlink:type="simple">mervehamzacelebioglu@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3212-9709</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильхан</surname><given-names>Э.</given-names></name><name name-style="western" xml:lang="en"><surname>İlhan</surname><given-names>E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Энвер Ильхан — врач, профессор, отделение общей хирургии </p><p>35170, г. Измир, Карабаглар, ул. Саим Чикрыкчи, 59 </p></bio><bio xml:lang="en"><p>Enver İlhan — M.D., Professor, Department of General Surgery, Izmir Bozyaka Training and Research Hospital, Izmir Faculty of Medicine </p><p>35170, Izmir, Karabağlar, Saim Çıkrıkçı str., 59 </p></bio><email xlink:type="simple">enverhan@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-7612-3402</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мерт Атесчи</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mert Ateşci</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ата Мерт Атесчи — врач, ассистент, отделение общей хирургии </p><p>35170, г. Измир, Карабаглар, ул. Саим Чикрыкчи, 59 </p></bio><bio xml:lang="en"><p>Ata Mert Ateşci — M.D., Teaching Assistant, Department of General Surgery, Izmir Bozyaka Training and Research Hospital, Izmir Faculty of Medicine </p><p>35170, Izmir, Karabağlar, Saim Çıkrıkçı str., 59 </p></bio><email xlink:type="simple">atamertatesci@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Измирская учебно-исследовательская больница, Измирский медицинский факультет Университета медицинских наук Турции</institution><country>Турция</country></aff><aff xml:lang="en"><institution>University of Health Sciences Turkey</institution><country>Turkey</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>01</month><year>2024</year></pub-date><volume>34</volume><issue>6</issue><fpage>94</fpage><lpage>99</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хамзачелебиоглу М., Урейн О., Аргон А., Ильхан Э., Мерт Атесчи А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Хамзачелебиоглу М., Урейн О., Аргон А., Ильхан Э., Мерт Атесчи А.</copyright-holder><copyright-holder xml:lang="en">Hamzaçelebioğlu M., Üreyen O., Argon A., İlhan E., Mert Ateşci A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1356">https://www.gastro-j.ru/jour/article/view/1356</self-uri><abstract><p>Цель: писать клиническую картину, лечение и исход случая солидной псевдопапиллярной опухоли (СППО) поджелудочной железы.Основные положения. СППО поджелудочной железы — редкие опухоли с низким злокачественным потенциалом, которые чаще всего встречаются у молодых женщин и обычно располагаются в хвосте поджелудочной железы. Хирургическая резекция СППО с негативными хирургическими краями связана с улучшением выживаемости и снижением вероятности рецидива. В данном исследовании мы рассматриваем случай лечения 69-летней женщины с СППО, возникшей в хвосте поджелудочной железы и распространившейся на ворота селезенки. Пациентке была проведена радикальная резекция с получением негативных хирургических краев. Однако впоследствии у нее развились метастазы в печень и легкие, что побудило начать системную химиотерапию. Пациентка умерла через семь месяцев после развития метастазов и через 39 месяцев после постановки первичного диагноза. Этот случай подчеркивает, что, несмотря на успешное хирургическое вмешательство, наличие гистопатологических признаков высокого риска может привести к рецидиву и метастазам, что требует пересмотра подходов к лечению.Заключение. Негативные хирургические края имеют ключевое значение для благоприятного прогноза при лечении СППО. Тем не менее необходим тщательный мониторинг на предмет возможного рецидива. Наши результаты показывают, что даже после резекции с негативными краями пациенты с высокими рисками должны находиться под строгим наблюдением и для них должна рассматриваться возможность послеоперационной системной химиотерапии. Этот клинический случай подчеркивает сложность лечения СППО поджелудочной железы и необходимость индивидуализированных стратегий, поскольку раннее выявление рецидива может значительно повлиять на результаты выживания.</p></abstract><trans-abstract xml:lang="en"><p>Aim: to discuss the clinical presentation, management, and outcome of the clinical case of solid pseudopapillary tumour of the pancreas (SPTP).Key points. SPTPs are rare tumours known for their low malignant potential. They are predominantly found in younger females, typically occurring in the tail of the pancreas. Surgical resection of SPTP with negative margins is associated with improved survival rates and lower chances of recurrence. In this study, we discuss the case of a 69-year-old woman diagnosed with an SPTP originating from the tail of the pancreas, which had spread to the hilum of the spleen. A radical resection was performed, successfully obtaining negative surgical margins. However, the patient subsequently developed metastasis to the liver and lungs, prompting the initiation of systemic chemotherapy. The patient died seven months after the development of metastasis and 39 months following the primary diagnosis. This case underscores that, despite initial successful surgical outcomes, high-risk histopathological features can lead to recurrence and metastasis, necessitating reassessment of treatment strategies.Conclusion. Negative surgical margins are critical for a favourable prognosis in the treatment of SPTPs; however, close monitoring for potential recurrence is essential. Our findings highlight that even after achieving negative margins, patients with high-risk features should undergo rigorous follow-up and consider postoperative systemic chemotherapy. This clinical case emphasizes the complexity of managing SPTP and the need for individualized treatment strategies, as early detection of recurrence can significantly influence survival outcomes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>солидно-псевдопапиллярная опухоль</kwd><kwd>поджелудочная железа</kwd><kwd>метастазы</kwd><kwd>хирургия</kwd><kwd>резекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>solid pseudopapillary tumor</kwd><kwd>pancreas</kwd><kwd>metastasis</kwd><kwd>surgery</kwd><kwd>resection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Anand G., Sharma D., Meena S., Guleria M., Nangia A. Resection of a large solid pseudopapillary neoplasm of the pancreas: A multidisciplinary feat and review of literature. Pol Przegl Chir. 2022;95(4):1–5. 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