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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1401</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВОСТИ КОЛОПРОКТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEWS OF COLOPROCTOLOGY</subject></subj-group></article-categories><title-group><article-title>Подготовка больных к проведению эндоскопических исследований и хирургических вмешательств на толстой кишке</article-title><trans-title-group xml:lang="en"><trans-title>Preparation of patients for endoscopic investigations and surgery of the large intestine</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Башанкаев</surname><given-names>Б. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bashankaev</surname><given-names>B. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Йулдашев</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuldashev</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермаков</surname><given-names>Д. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Yermakov</surname><given-names>D. F.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Царьков</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsarkov</surname><given-names>P. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>РНЦХ им. Б.В. Петровского РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2011</year></pub-date><volume>21</volume><issue>2</issue><fpage>76</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Башанкаев Б.Н., Йулдашев А.Г., Ермаков Д.Ф., Царьков П.В., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Башанкаев Б.Н., Йулдашев А.Г., Ермаков Д.Ф., Царьков П.В.</copyright-holder><copyright-holder xml:lang="en">Bashankaev B.N., Yuldashev A.G., Yermakov D.F., Tsarkov P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1401">https://www.gastro-j.ru/jour/article/view/1401</self-uri><abstract><p>Цель обзора. Осветить современную тактику подготовки больных к эндоскопическим исследованиям и проведению хирургических вмешательств на толстой кишке.Основные положения. Благодаря использованию полиэтиленгликоля (ПЭГ) обязательная очистка толстой кишки стала возможной без применения очистительных клизм. ПЭГ является высокомолекулярным линейным полимером, связывающим воду, что увеличивает объем содержащейся в кишечнике жидкости и стимулирует механорецепторы. В качестве альтернативного способа применяются препараты фосфатов натрия. Ограничивает их применение возможное развитие гиперфосфатемии у некоторых категорий больных. Подготовка толстой кишки к эндоскопическим исследованиям для обеспечения информативности процедуры требует отличного очищения просвета кишки. Перед плановыми вмешательствами подготовка необходима при лапароскопической хирургии и операциях на прямой кишке. Представлен собственный опыт ведения колоректальных больных в предоперационном периоде.Заключение. Применение препаратов ПЭГ позволяет относительно безопасно достичь качественной подготовки к хирургическим и эндоскопическим вмешательствам на толстой и прямой кишке с наименьшим количеством относительных и абсолютных противопоказаний.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of review</title><p>The aim of review. To demonstrate modern approach to preparation of patients for endoscopy and colon and rectal surgery.</p></sec><sec><title>Original positions</title><p>Original positions. Due to application of polyethylene glycol (PEG) obligatory cleaning of the large intestine became possible without application of flush enemas. PEG is high molecular weight linear polymer retaining water that increases fluid volume in the bowel and stimulates mechanoreceptors. Application of sodium phosphates is an alternative preparation method. Risk of hyperphosphatemia that develops in some groups of patients limits their application. Preparation with excellent cleaning of large intestinal lumen is necessary for conclusive endoscopic investigation. Preparation is required as well before elective laparoscopic and rectal surgery. Authors’ experience of preoperative management of colorectal patients is presented.</p></sec><sec><title>Conclusion</title><p>Conclusion. Application of PEG agents allows to obtain safely high-quality preparation for surgical and endoscopic colorectal interventions with the least number of relative and absolute contraindications.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальная хирургия</kwd><kwd>колопроктология</kwd><kwd>подготовка толстой кишки</kwd><kwd>эндоскопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal surgery</kwd><kwd>coloproctology</kwd><kwd>bowel preparation</kwd><kwd>endoscopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2006 г. // Вестн. рос. онкол. науч. центра им. Н.Н. Блохина РАМН. – 2008. – Т. 19, № 2 (suppl. 1). – С. 154.</mixed-citation><mixed-citation xml:lang="en">Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2006 г. // Вестн. рос. онкол. науч. центра им. Н.Н. Блохина РАМН. – 2008. – Т. 19, № 2 (suppl. 1). – С. 154.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кашин С.В. и др. Новые методики эндоскопического скрининга предопухолевой патологии и колоректального рака и необходимые условия их эффективного применения в клинической практике // Клин. эндоскопия. – 2009. – Т. 3, № 20. – С. 7–13.</mixed-citation><mixed-citation xml:lang="en">Кашин С.В. и др. Новые методики эндоскопического скрининга предопухолевой патологии и колоректального рака и необходимые условия их эффективного применения в клинической практике // Клин. эндоскопия. – 2009. – Т. 3, № 20. – С. 7–13.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Никифоров П.А. и др. Успешный десятилетний опыт применения препарата «Фортранс®» в клинической практике для подготовки к колоноскопии // Вестн. хир. гастроэнтерол. – 2008. – Т. 2. – С. 62–66.</mixed-citation><mixed-citation xml:lang="en">Никифоров П.А. и др. Успешный десятилетний опыт применения препарата «Фортранс®» в клинической практике для подготовки к колоноскопии // Вестн. хир. гастроэнтерол. – 2008. – Т. 2. – С. 62–66.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Никифоров П.А., Голубева С., Базарова М.А., Гранков С.С. Использование препарата фортранc в подготовке к колофиброскопии и эндоскопической полипэктомии // Рос. журн. гастроэнтерол. гепатол. колопроктол. – 1999. – Т. 19, № 5. – С. 1–4.</mixed-citation><mixed-citation xml:lang="en">Никифоров П.А., Голубева С., Базарова М.А., Гранков С.С. Использование препарата фортранc в подготовке к колофиброскопии и эндоскопической полипэктомии // Рос. журн. гастроэнтерол. гепатол. колопроктол. – 1999. – Т. 19, № 5. – С. 1–4.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Самедов Б.Х. Подготовка больных к инструментальным исследованиям кишечника и забрюшинного пространства: многолетний клинический опыт применения Фортранса // Клин. эндоскопия. – 2009. – Т. 4, № 21. – С. 18–24.</mixed-citation><mixed-citation xml:lang="en">Самедов Б.Х. Подготовка больных к инструментальным исследованиям кишечника и забрюшинного пространства: многолетний клинический опыт применения Фортранса // Клин. эндоскопия. – 2009. – Т. 4, № 21. – С. 18–24.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Brown A.R., DiPalma J.A. Bowel preparation for gastrointestinal procedures // Curr. Gastroenterol. Rep. – 2004. – Vol. 6, N 5. – P. 395–401.</mixed-citation><mixed-citation xml:lang="en">Brown A.R., DiPalma J.A. Bowel preparation for gastrointestinal procedures // Curr. Gastroenterol. Rep. – 2004. – Vol. 6, N 5. – P. 395–401.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bucher P., Mermillod B., Gervaz P., Morel P. Mechanical bowel preparation for elective colorectal surgery: a meta-analysis // Arch. Surg. – 2004. – Vol. 139, N 12. – P. 1359–1364; discussion 1365.</mixed-citation><mixed-citation xml:lang="en">Bucher P., Mermillod B., Gervaz P., Morel P. Mechanical bowel preparation for elective colorectal surgery: a meta-analysis // Arch. Surg. – 2004. – Vol. 139, N 12. – P. 1359–1364; discussion 1365.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chung Y.W. et al. Patient factors predictive of inadequate bowel preparation using polyethylene glycol: a prospective study in Korea // J. Clin. Gastroenterol. – 2009. – Vol. 43, N 5. – P. 448–452.</mixed-citation><mixed-citation xml:lang="en">Chung Y.W. et al. Patient factors predictive of inadequate bowel preparation using polyethylene glycol: a prospective study in Korea // J. Clin. Gastroenterol. – 2009. – Vol. 43, N 5. – P. 448–452.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Carcinoma of the Colon / Ed. M.L. Corman // Colon and rectal surgery. – Philadelphia: Lippincott, 2005. – P. 22. – 978-0-7817-4043-2 – P. 767–903.</mixed-citation><mixed-citation xml:lang="en">Carcinoma of the Colon / Ed. M.L. Corman // Colon and rectal surgery. – Philadelphia: Lippincott, 2005. – P. 22. – 978-0-7817-4043-2 – P. 767–903.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">http://www.nhmrc.gov.au/publications/synopses/cp106/cp106divided.htm, chapter 10.</mixed-citation><mixed-citation xml:lang="en">http://www.nhmrc.gov.au/publications/synopses/cp106/cp106divided.htm, chapter 10.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Davis G.R., Santa Ana C.A., Morawski S.G., Fordtran J.S. Development of a lavage solution associated with minimal water and electrolyte absorption or secretion // Gastroenterology. – 1980. – Vol. 78, N 5 (Pt. 1). – P. 991–995.</mixed-citation><mixed-citation xml:lang="en">Davis G.R., Santa Ana C.A., Morawski S.G., Fordtran J.S. Development of a lavage solution associated with minimal water and electrolyte absorption or secretion // Gastroenterology. – 1980. – Vol. 78, N 5 (Pt. 1). – P. 991–995.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Duthie G.S., Foster M.E., Price-Thomas J.M., Leaper D.J. Bowel preparation or not for elective colorectal surgery // J. R. Coll. Surg. Edinb. – 1990. – Vol. 35, N 3. – P. 169–171.</mixed-citation><mixed-citation xml:lang="en">Duthie G.S., Foster M.E., Price-Thomas J.M., Leaper D.J. Bowel preparation or not for elective colorectal surgery // J. R. Coll. Surg. Edinb. – 1990. – Vol. 35, N 3. – P. 169–171.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">FDA Oral Sodium Phosphate (OSP) Products for Bowel Cleansing (marketed as Visicol and OsmoPrep, and oral sodium phosphate products available without a prescription) [Online]. – http://www.fda.gov/Drugs/ DrugSafety/PostmarketDrugSafetyInformationforPatient sandProviders/ucm103354.htm.</mixed-citation><mixed-citation xml:lang="en">FDA Oral Sodium Phosphate (OSP) Products for Bowel Cleansing (marketed as Visicol and OsmoPrep, and oral sodium phosphate products available without a prescription) [Online]. – http://www.fda.gov/Drugs/ DrugSafety/PostmarketDrugSafetyInformationforPatient sandProviders/ucm103354.htm.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Feres O., Monteiro dos Santos Jr. J.C., Andrade J.I. The role of mechanical bowel preparation for colonic resection and anastomosis: an experimental study // Int. J. Colorectal Dis. – 2001. – Vol. 16, N 6. – P. 353–356.</mixed-citation><mixed-citation xml:lang="en">Feres O., Monteiro dos Santos Jr. J.C., Andrade J.I. The role of mechanical bowel preparation for colonic resection and anastomosis: an experimental study // Int. J. Colorectal Dis. – 2001. – Vol. 16, N 6. – P. 353–356.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gravante G., Caruso R., Andreani S.M., Giordano P. Mechanical bowel preparation for colorectal surgery: a meta-analysis on abdominal and systemic complications on almost 5,000 patients // Int. J. Colorectal Dis. – 2008. – Vol. 23, N 12. – P. 1145–1150.</mixed-citation><mixed-citation xml:lang="en">Gravante G., Caruso R., Andreani S.M., Giordano P. Mechanical bowel preparation for colorectal surgery: a meta-analysis on abdominal and systemic complications on almost 5,000 patients // Int. J. Colorectal Dis. – 2008. – Vol. 23, N 12. – P. 1145–1150.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Guenaga K.K., Matos D., Wille-Jorgensen P. Mechanical bowel preparation for elective colorectal surgery // Cochrane Database Syst. Rev. – 2009. – N 1. – P. CD001544.</mixed-citation><mixed-citation xml:lang="en">Guenaga K.K., Matos D., Wille-Jorgensen P. Mechanical bowel preparation for elective colorectal surgery // Cochrane Database Syst. Rev. – 2009. – N 1. – P. CD001544.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Harewood G.C., Sharma V.K., de Garmo P. Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia // Gastrointest. Endosc. – 2003. – Vol. 58, N 1. – P. 76–79.</mixed-citation><mixed-citation xml:lang="en">Harewood G.C., Sharma V.K., de Garmo P. Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia // Gastrointest. Endosc. – 2003. – Vol. 58, N 1. – P. 76–79.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Hughes E.S. Asepsis in large-bowel surgery // Ann. R. Coll. Surg. Engl. – 1972. – Vol. 51, N 6. – P. 347–356.</mixed-citation><mixed-citation xml:lang="en">Hughes E.S. Asepsis in large-bowel surgery // Ann. R. Coll. Surg. Engl. – 1972. – Vol. 51, N 6. – P. 347–356.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Irving A.D., Scrimgeour D. Mechanical bowel preparation for colonic resection and anastomosis // Br. J. Surg. – 1987. – Vol. 74, N 7. – P. 580–581.</mixed-citation><mixed-citation xml:lang="en">Irving A.D., Scrimgeour D. Mechanical bowel preparation for colonic resection and anastomosis // Br. J. Surg. – 1987. – Vol. 74, N 7. – P. 580–581.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Jemal A., Siegel R., Xu J., Ward E. Cancer statistics, 2010 // CA Cancer J. Clin. – 2010. – Vol. 60, N 5. – P. 277–300.</mixed-citation><mixed-citation xml:lang="en">Jemal A., Siegel R., Xu J., Ward E. Cancer statistics, 2010 // CA Cancer J. Clin. – 2010. – Vol. 60, N 5. – P. 277–300.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Lawrence E.M., Pickhardt P.J. Low-volume hybrid bowel preparation combining saline laxatives with oral contrast agents versus standard polyethylene glycol lavage for colonoscopy // Dis. Colon Rectum. – 2010. – Vol. 53, N 8. – P. 1176–1181.</mixed-citation><mixed-citation xml:lang="en">Lawrence E.M., Pickhardt P.J. Low-volume hybrid bowel preparation combining saline laxatives with oral contrast agents versus standard polyethylene glycol lavage for colonoscopy // Dis. Colon Rectum. – 2010. – Vol. 53, N 8. – P. 1176–1181.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Lebwohl B., Wang T.C., Neugut A.I. Socioeconomic and other predictors of colonoscopy preparation quality // Dig. Dis. Sci. – 2010. – Vol. 55, N 7. – P. 2014–2020.</mixed-citation><mixed-citation xml:lang="en">Lebwohl B., Wang T.C., Neugut A.I. Socioeconomic and other predictors of colonoscopy preparation quality // Dig. Dis. Sci. – 2010. – Vol. 55, N 7. – P. 2014–2020.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Levin B. et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology // Gastroenterology. – 2008. – Vol. 134, N 5. – P. 1570–1595.</mixed-citation><mixed-citation xml:lang="en">Levin B. et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology // Gastroenterology. – 2008. – Vol. 134, N 5. – P. 1570–1595.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Miettinen R.P., Laitinen S.T., Makela J.T., Paakkonen M.E. Bowel preparation with oral polyethylene glycol electrolyte solution vs. no preparation in elective open colorectal surgery: prospective, randomized study // Dis. Colon Rectum. – 2000. – Vol. 43, N 5. – P. 669–675; discussion 675–667.</mixed-citation><mixed-citation xml:lang="en">Miettinen R.P., Laitinen S.T., Makela J.T., Paakkonen M.E. Bowel preparation with oral polyethylene glycol electrolyte solution vs. no preparation in elective open colorectal surgery: prospective, randomized study // Dis. Colon Rectum. – 2000. – Vol. 43, N 5. – P. 669–675; discussion 675–667.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Ness R.M., Manam R., Hoen H., Chalasani N. Predictors of inadequate bowel preparation for colonoscopy // Am. J. Gastroenterol. – 2001. – Vol. 96, N 6. – P. 1797–1802.</mixed-citation><mixed-citation xml:lang="en">Ness R.M., Manam R., Hoen H., Chalasani N. Predictors of inadequate bowel preparation for colonoscopy // Am. J. Gastroenterol. – 2001. – Vol. 96, N 6. – P. 1797–1802.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Otchy D. et al. Practice parameters for colon cancer // Dis. Colon Rectum. – 2004. – Vol. 47, N 8. – P. 1269–1284.</mixed-citation><mixed-citation xml:lang="en">Otchy D. et al. Practice parameters for colon cancer // Dis. Colon Rectum. – 2004. – Vol. 47, N 8. – P. 1269–1284.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Pineda C.E. et al. Mechanical bowel preparation in intestinal surgery: a meta-analysis and review of the literature // J. Gastrointest. Surg. – 2008. – Vol. 12, N 11. – P. 2037–2044.</mixed-citation><mixed-citation xml:lang="en">Pineda C.E. et al. Mechanical bowel preparation in intestinal surgery: a meta-analysis and review of the literature // J. Gastrointest. Surg. – 2008. – Vol. 12, N 11. – P. 2037–2044.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Rosch T., Classen M. Fractional cleansing of the large bowel with «Golytely» for colonoscopic preparation: a controlled trial // Endoscopy. – 1987. – Vol. 19, N 5. – P. 198–200.</mixed-citation><mixed-citation xml:lang="en">Rosch T., Classen M. Fractional cleansing of the large bowel with «Golytely» for colonoscopic preparation: a controlled trial // Endoscopy. – 1987. – Vol. 19, N 5. – P. 198–200.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Schein M., Assalia A., Eldar S., Wittmann D.H. Is mechanical bowel preparation necessary before primary colonic anastomosis? An experimental study // Dis. Colon Rectum. – 1995. – Vol. 38, N 7. – P. 749–752; discussion 752–744.</mixed-citation><mixed-citation xml:lang="en">Schein M., Assalia A., Eldar S., Wittmann D.H. Is mechanical bowel preparation necessary before primary colonic anastomosis? An experimental study // Dis. Colon Rectum. – 1995. – Vol. 38, N 7. – P. 749–752; discussion 752–744.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Seeff L.C. et al. How many endoscopies are performed for colorectal cancer screening? Results from CDC’s survey of endoscopic capacity // Gastroenterology. – 2004. – Vol. 127, N 6. – P. 1670–1677.</mixed-citation><mixed-citation xml:lang="en">Seeff L.C. et al. How many endoscopies are performed for colorectal cancer screening? Results from CDC’s survey of endoscopic capacity // Gastroenterology. – 2004. – Vol. 127, N 6. – P. 1670–1677.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Shawki S., Wexner S.D. Oral colorectal cleansing preparations in adults // Drugs. – 2008. – Vol. 68, N 4. – P. 417–437.</mixed-citation><mixed-citation xml:lang="en">Shawki S., Wexner S.D. Oral colorectal cleansing preparations in adults // Drugs. – 2008. – Vol. 68, N 4. – P. 417–437.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Slim K. et al. Updated systematic review and metaanalysis of randomized clinical trials on the role of mechanical bowel preparation before colorectal surgery // Ann. Surg. – 2009. – Vol. 249, N 2. – P. 203–209.</mixed-citation><mixed-citation xml:lang="en">Slim K. et al. Updated systematic review and metaanalysis of randomized clinical trials on the role of mechanical bowel preparation before colorectal surgery // Ann. Surg. – 2009. – Vol. 249, N 2. – P. 203–209.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">van Geldere D. et al. Complications after colorectal surgery without mechanical bowel preparation // J. Am. Coll. Surg. – 2002. – Vol. 194, N 1. – P. 40–47.</mixed-citation><mixed-citation xml:lang="en">van Geldere D. et al. Complications after colorectal surgery without mechanical bowel preparation // J. Am. Coll. Surg. – 2002. – Vol. 194, N 1. – P. 40–47.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Van’t Sant H.P. et al. The influence of mechanical bowel preparation in elective lower colorectal surgery // Ann. Surg. – 2010. – Vol. 251, N 1. – P. 59–63.</mixed-citation><mixed-citation xml:lang="en">Van’t Sant H.P. et al. The influence of mechanical bowel preparation in elective lower colorectal surgery // Ann. Surg. – 2010. – Vol. 251, N 1. – P. 59–63.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Vanner S.J. et al. A randomized prospective trial comparing oral sodium phosphate with standard polyethylene glycolbased lavage solution (Golytely) in the preparation of patients for colonoscopy // Am. J. Gastroenterol. – 1990. – Vol. 85, N 4. – P. 422–427.</mixed-citation><mixed-citation xml:lang="en">Vanner S.J. et al. A randomized prospective trial comparing oral sodium phosphate with standard polyethylene glycolbased lavage solution (Golytely) in the preparation of patients for colonoscopy // Am. J. Gastroenterol. – 1990. – Vol. 85, N 4. – P. 422–427.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Vijan S. et al. Projections of demand and capacity for colonoscopy related to increasing rates of colorectal cancer screening in the United States // Aliment. Pharmacol. Ther. – 2004. – Vol. 20, N 5. – P. 507–515.</mixed-citation><mixed-citation xml:lang="en">Vijan S. et al. Projections of demand and capacity for colonoscopy related to increasing rates of colorectal cancer screening in the United States // Aliment. Pharmacol. Ther. – 2004. – Vol. 20, N 5. – P. 507–515.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Watanabe M. et al. Randomized clinical trial of the influence of mechanical bowel preparation on faecal microflora in patients undergoing colonic cancer resection // Br. J. Surg. – 2010.</mixed-citation><mixed-citation xml:lang="en">Watanabe M. et al. Randomized clinical trial of the influence of mechanical bowel preparation on faecal microflora in patients undergoing colonic cancer resection // Br. J. Surg. – 2010.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Wexner S.D. et al. A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) // Dis. Colon Rectum. – 2006. – Vol. 49, N 6. – P. 792–809.</mixed-citation><mixed-citation xml:lang="en">Wexner S.D. et al. A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) // Dis. Colon Rectum. – 2006. – Vol. 49, N 6. – P. 792–809.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Wolff W.I., Shinya H. Colonofiberoscopy // JAMA. – 1971. – Vol. 217, N 11. – P. 1509–1512.</mixed-citation><mixed-citation xml:lang="en">Wolff W.I., Shinya H. Colonofiberoscopy // JAMA. – 1971. – Vol. 217, N 11. – P. 1509–1512.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization Global cancer rates could increase by 50% to 15 million by 2020 [Online]. – 12/09, 2010. – http://www.who.int/mediacentre/news/releases/2003/pr27/en/.</mixed-citation><mixed-citation xml:lang="en">World Health Organization Global cancer rates could increase by 50% to 15 million by 2020 [Online]. – 12/09, 2010. – http://www.who.int/mediacentre/news/releases/2003/pr27/en/.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization Cancer [Online]. – 12/09, 2010. – http://www.who.int/mediacentre/factsheets/fs297/en/index.html.</mixed-citation><mixed-citation xml:lang="en">World Health Organization Cancer [Online]. – 12/09, 2010. – http://www.who.int/mediacentre/factsheets/fs297/en/index.html.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Zmora O. et al. Colon and rectal surgery without mechanical bowel preparation: a randomized prospective trial // Ann. Surg. – 2003. – Vol. 237, N 3. – P. 363–367.</mixed-citation><mixed-citation xml:lang="en">Zmora O. et al. Colon and rectal surgery without mechanical bowel preparation: a randomized prospective trial // Ann. Surg. – 2003. – Vol. 237, N 3. – P. 363–367.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Zmora O., Pikarsky A.J., Wexner S.D. Bowel preparation for colorectal surgery // Dis. Colon Rectum. – 2001. – Vol. 44, N 10. – P. 1537–1549.</mixed-citation><mixed-citation xml:lang="en">Zmora O., Pikarsky A.J., Wexner S.D. Bowel preparation for colorectal surgery // Dis. Colon Rectum. – 2001. – Vol. 44, N 10. – P. 1537–1549.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
