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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1410</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Клинические особенности хронического панкреатита у больных пожилого возраста с выраженным атеросклерозом мезентериальных сосудов</article-title><trans-title-group xml:lang="en"><trans-title>Clinical features of chronic pancreatitis at elderly patients with severe mesenteric atherosclerosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шифрин</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shifrin</surname><given-names>O. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolina</surname><given-names>I. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лемина</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lemina</surname><given-names>T. L.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>04</day><month>05</month><year>2011</year></pub-date><volume>21</volume><issue>3</issue><fpage>35</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шифрин О.С., Соколина И.А., Лемина Т.Л., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Шифрин О.С., Соколина И.А., Лемина Т.Л.</copyright-holder><copyright-holder xml:lang="en">Shifrin O.S., Sokolina I.A., Lemina T.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1410">https://www.gastro-j.ru/jour/article/view/1410</self-uri><abstract><p>Цель исследования. Изучить клинические особенности течения болезни у больных хроническим панкреатитом с выраженными атеросклеротическими изменениями мезентериальных сосудов (кальциноз чревного ствола).Материал и методы. Было обследовано 290 пациентов с установленным диагнозом хронического панкреатита. На основании алкогольной и билиарной этиологии заболевания, выявленной при компьютерной томографии с болюсным контрастированием изменений (кальциноз устья чревного ствола и верхней брыжеечной артерии), 43 пациента выделены в группу с «ишемической составляющей».Результаты. Больные данной группы характеризовались рядом особенностей: более старший возраст, меньшая выраженность болей, повышенная частота ишемической болезни сердца и гипертонической болезни. У них чаще диагностировались также гастродуоденальные эрозивные изменения с относительной резистентностью к проводимой лекарственной терапии.Заключение. У пациентов пожилого возраста, страдающих хроническим панкреатитом и кальцинозом мезентериальных сосудов, в лечении абдоминальной боли с учетом частых жалоб на наличие запоров высокую эффективность показали таблетированные препараты панкреатина (Мезим® 10 000).</p></abstract><trans-abstract xml:lang="en"><sec><title>Aim of investigation</title><p>Aim of investigation. To study clinical features of chronic pancreatitis in patients with severe mesenteric atherosclerosis (calcification of celiac trunk).</p></sec><sec><title>Material and methods</title><p>Material and methods. Overall 290 patients with chronic pancreatitis have been investigated. According to alcoholic and biliary etiology of disease, signs that was revealed at computer tomography with bolus contrast injection (calcification of ostium of celiac trunk and superior mesenteric artery), 43 patients were selected to the group with «ischemic component».</p></sec><sec><title>Results</title><p>Results. Patients of this group were characterized by series of features: older age, lower intensity of pain, higher frequency of ischemic heart disease and systemic hypertension. Gastroduodenal erosions with relative resistance to drug treatment were more frequently diagnosed in these patients.</p></sec><sec><title>Conclusion</title><p>Conclusion. At elderly patients with chronic pancreatitis and calcification of mesenteric blood vessels, with respect to frequent constipation tablet pancreatin agents (Mezym® 10000) have high efficacy in treatment of abdominal pain.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический панкреатит</kwd><kwd>кальциноз чревного ствола</kwd><kwd>компьютерная томография</kwd><kwd>препараты панкреатина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic pancreatitis</kwd><kwd>calcification of celiac trunk</kwd><kwd>computer tomography</kwd><kwd>pancreatin preparations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гастроэнтерология «Национальное руководство» / Под. ред. В.Т. Ивашкина, Т.Л. Лапиной. – М.: «ГЭОТАРМЕДИА», 2008. – 700 с.</mixed-citation><mixed-citation xml:lang="en">Гастроэнтерология «Национальное руководство» / Под. ред. В.Т. Ивашкина, Т.Л. Лапиной. – М.: «ГЭОТАРМЕДИА», 2008. – 700 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Рациональная фармакотерапия заболеваний органов пищеварения / Под общей ред. В.Т. Ивашкина, Т.Н. Лапиной. – М.: Литерра, 2006. – С. 205–258.</mixed-citation><mixed-citation xml:lang="en">Рациональная фармакотерапия заболеваний органов пищеварения / Под общей ред. В.Т. Ивашкина, Т.Н. Лапиной. – М.: Литерра, 2006. – С. 205–258.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Савельев В.С. Петухов В.А. Бычков С.Г. и др. Нарушения микроциркуляции при хронической ишемической болезни органов пищеварения и дислипопротеидемии // Грудн. и сердечно-сосуд. хирургия. – 1999. – № 4. – С. 40–45.</mixed-citation><mixed-citation xml:lang="en">Савельев В.С. Петухов В.А. Бычков С.Г. и др. Нарушения микроциркуляции при хронической ишемической болезни органов пищеварения и дислипопротеидемии // Грудн. и сердечно-сосуд. хирургия. – 1999. – № 4. – С. 40–45.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bourliere M., Barthet M., Berthezene P. еt al. Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis? // Gut. – 1991. – Vol. 32. – P. 1392–1395.</mixed-citation><mixed-citation xml:lang="en">Bourliere M., Barthet M., Berthezene P. еt al. Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis? // Gut. – 1991. – Vol. 32. – P. 1392–1395.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Busquet J. Intravascular stenting in the superior mesenteric artery of chronic abdominal angina // J. Endovass. Surg. – 1997. – Vol. 4, N 4. – P. 380–384.</mixed-citation><mixed-citation xml:lang="en">Busquet J. Intravascular stenting in the superior mesenteric artery of chronic abdominal angina // J. Endovass. Surg. – 1997. – Vol. 4, N 4. – P. 380–384.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cappeller W.A., Kettmann R., Behrmann C. Surgical therapy of chronic visceral arterial ischemia with aortoceliac, mesenteric patch bypass // Chirurg. – 1998. – Vol.69. – P. 6422–6649.</mixed-citation><mixed-citation xml:lang="en">Cappeller W.A., Kettmann R., Behrmann C. Surgical therapy of chronic visceral arterial ischemia with aortoceliac, mesenteric patch bypass // Chirurg. – 1998. – Vol.69. – P. 6422–6649.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Clowdhury P., Bone R.C., Louria D.B., Rayford P.L. Effect of cigarette smoke on human serum inhibitory capacity and antitripsin concentration // Rev. Respir. Dis. – 1982. – Vol. 126. – P. 177–179.</mixed-citation><mixed-citation xml:lang="en">Clowdhury P., Bone R.C., Louria D.B., Rayford P.L. Effect of cigarette smoke on human serum inhibitory capacity and antitripsin concentration // Rev. Respir. Dis. – 1982. – Vol. 126. – P. 177–179.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Foitsik T., Buhr H.J. New aspects in the pathophysiology of chronic pancreatitis // Chirurg. – 1997. – Vol. 68, N 9. – P. 855–864.</mixed-citation><mixed-citation xml:lang="en">Foitsik T., Buhr H.J. New aspects in the pathophysiology of chronic pancreatitis // Chirurg. – 1997. – Vol. 68, N 9. – P. 855–864.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fortson M.R., Freedman S.N., Webster B.D. Clinical assessment of hyperlipidemic pancreatitis // Am. J. Gastroenterol. – 1995. – Vol. 90. – P. 2134–2139.</mixed-citation><mixed-citation xml:lang="en">Fortson M.R., Freedman S.N., Webster B.D. Clinical assessment of hyperlipidemic pancreatitis // Am. J. Gastroenterol. – 1995. – Vol. 90. – P. 2134–2139.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hamed R.V., Ghanduor T.N. Abdominal angina and intestinal gangrene – a catastrophic presentation of arterial fibromuscular dysplasia case report and review of the literature // J. Pediatr. Surg. – 1997. – Vol. 32, N 9. – P. 1379–1380.</mixed-citation><mixed-citation xml:lang="en">Hamed R.V., Ghanduor T.N. Abdominal angina and intestinal gangrene – a catastrophic presentation of arterial fibromuscular dysplasia case report and review of the literature // J. Pediatr. Surg. – 1997. – Vol. 32, N 9. – P. 1379–1380.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Harward T.R., Weiborn M.B., Martin T.D. et al. Visceral ischemia and organ dysfunction after thoracoabdominal aortic aneurism repair. A clinical and cost analisis // Ann. Surg. – 1996. – Vol. 223. – P. 729–734.</mixed-citation><mixed-citation xml:lang="en">Harward T.R., Weiborn M.B., Martin T.D. et al. Visceral ischemia and organ dysfunction after thoracoabdominal aortic aneurism repair. A clinical and cost analisis // Ann. Surg. – 1996. – Vol. 223. – P. 729–734.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Levy P., Mathurin P., Rogueplo A. et al. A multidimensional case control study of dietary alcohol and tobacco habits in alcoholic men with chronic pancreatitis // Pancreas. – 1995. – P. 106231–106238.</mixed-citation><mixed-citation xml:lang="en">Levy P., Mathurin P., Rogueplo A. et al. A multidimensional case control study of dietary alcohol and tobacco habits in alcoholic men with chronic pancreatitis // Pancreas. – 1995. – P. 106231–106238.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Pitchumoni C.S. Role of nutrition in chronic pancreatitis // Chronic Pancreatitis / Eds. H. Beger, M. Buchler, H. Ditschuneit, P. Malfertheiner. – Berlin: Heidelberg Springer-Ferlag, 1990. – P. 15–25.</mixed-citation><mixed-citation xml:lang="en">Pitchumoni C.S. Role of nutrition in chronic pancreatitis // Chronic Pancreatitis / Eds. H. Beger, M. Buchler, H. Ditschuneit, P. Malfertheiner. – Berlin: Heidelberg Springer-Ferlag, 1990. – P. 15–25.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Toskes P.P. Hyperlipidemic pancreatitis // Gastroenterol. Clin. North Am. – 1990. – Vol. 19, N 4. – P. 783–791.</mixed-citation><mixed-citation xml:lang="en">Toskes P.P. Hyperlipidemic pancreatitis // Gastroenterol. Clin. North Am. – 1990. – Vol. 19, N 4. – P. 783–791.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
