gastro-jРоссийский журнал гастроэнтерологии, гепатологии, колопроктологииRussian Journal of Gastroenterology, Hepatology, Coloproctology1382-43762658-6673«Gastro» LLCgastro-j-1440Research ArticleНОВОСТИ КОЛОПРОКТОЛОГИИNEWS OF COLOPROCTOLOGYРезультаты эндоскопического лечения раннего рака толстой кишкиResults of endoscopic treatment of early colorectal cancerАгаповМ. Ю.AgapovM. Yu.ТаранН. А.TaranN. A.ПолушинО. Г.PolushinO. G.СтегнийК. В.StegnyK. V.2011060620112146065Copyright © Агапов М.Ю., Таран Н.А., Полушин О.Г., Стегний К.В., 20112011Агапов М.Ю., Таран Н.А., Полушин О.Г., Стегний К.В.Agapov M.Y., Taran N.A., Polushin O.G., Stegny K.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gastro-j.ru/jour/article/view/1440

Цель исследования. Оценить результаты обследования и эндоскопического лечения пациентов с подозрением на ранний колоректальный рак (РКР).Материал и методы. В исследование включено 46 пациентов с подозрением на РКР за период2006–2010 гг.Результаты. Образования чаще всего локализовались в левой половине толстой кишки (45,6%), относились к типу Is (52,2%). Средний размер – 17,1±6 мм. Симптом «none-lifting sign» обладал большей чувствительностью и специфичностью (88 и 100%) для дифференцировки глубокой и поверхностной/отсутствующей инвазии, чем рисунок кишечных ямок (68 и 92%). При соблюдении установленных критериев (высокая или умеренная дифференцировка опухоли, отсутствие злокачественных клеток по линии струпа, отсутствие инвазии в сосуды, отсутствие «отсевов», подслизистая инвазия не более 1000 мкм или 2-й уровень по Haggit) не было отмечено ни одного случая местного рецидива или метастатического поражения после эндоскопического удаления опухоли.Выводы. Эндоскопическое удаление ранних новообразований толстой кишки является эффективным методом лечения при условии строгого соблюдения критериев радикальности.

Aim of investigation

Aim of investigation. To estimate results of diagnostics and endoscopic treatment of patients with suspicion for early colorectal cancer (ECRC).

Material and methods

Material and methods. Overall 46 patients were included in original study with suspicion for ECRC in the period from 2006 to 2010.

Results

Results. Lesions were localized in the left side of the large intestine (45,6%) more frequently, referred into to the type Is (52,2%). The average size was 17,1±6 mm. The «none-lifting sign» had the greater sensitivity and specificity (88 and 100%) for differentiation of penetrating and superficial/no invasion, than intestinal fossas pattern (68 and 92%). At following accepted criteria (high or moderate grade of tumor differentiation, absence of malignant cells at the crust line, absence of vessel invasion, absence of secondary foci, submucosal invasion of no more than 1000 µm or 2-nd Haggit level) no local relapses or metastatic lesions after endoscopic tumor removal were detected.

Conclusions

Conclusions. Endoscopic erasion of early neoplasms of the large intestine is an effictive method of treatment at strict following of radical surgery criteria.

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The authors declare that there are no conflicts of interest present.