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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1457</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВОСТИ КОЛОПРОКТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEWS OF COLOPROCTOLOGY</subject></subj-group></article-categories><title-group><article-title>Экстирпация прямой кишки по поводу рака у больного с декомпенсированным циррозом печени и портальной гипертензией</article-title><trans-title-group xml:lang="en"><trans-title>Extirpation of rectum for cancer in patient with decompensated liver cirrhosis and portal hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Царьков</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsarkov</surname><given-names>P. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебезев</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebezev</surname><given-names>V. M.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стамов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Stamov</surname><given-names>V. I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никода</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikoda</surname><given-names>V. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кравченко</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kravchenko</surname><given-names>A. Yu.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Любивый</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyubivy</surname><given-names>Ye. D.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Башанкаев</surname><given-names>Б. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bashankayev</surname><given-names>B. N.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilov</surname><given-names>M. A.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>12</day><month>09</month><year>2011</year></pub-date><volume>21</volume><issue>5</issue><fpage>82</fpage><lpage>89</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Царьков П.В., Лебезев В.М., Стамов В.И., Никода В.В., Кравченко А.Ю., Любивый Е.Д., Башанкаев Б.Н., Данилов М.А., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Царьков П.В., Лебезев В.М., Стамов В.И., Никода В.В., Кравченко А.Ю., Любивый Е.Д., Башанкаев Б.Н., Данилов М.А.</copyright-holder><copyright-holder xml:lang="en">Tsarkov P.V., Lebezev V.M., Stamov V.I., Nikoda V.V., Kravchenko A.Y., Lyubivy Y.D., Bashankayev B.N., Danilov M.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1457">https://www.gastro-j.ru/jour/article/view/1457</self-uri><abstract><p>Цель публикации. Оценить эффективность мультидисциплинарного подхода в лечении больных раком прямой кишки, сочетающимся с портальной гипертензией и циррозом печени на примере клинического наблюдения.Основные положения. Больному 71 года (диагностированы рак нижнеампулярного отдела прямой кишки и сопутствующие заболевания – декомпенсированный цирроз печени, портальная гипертензия с варикозным расширением вен пищевода и желудка, печеночно-клеточная недостаточность класса С по классификации Чайлда–Пью) выполнена одномоментная брюшно-промежностная экстирпация прямой кишки с парааортальной лимфаденэктомией, формированием концевой забрюшинной колостомы, спленэктомией, деваскуляризацией желудка, гастротомией с прошиванием варикознорасширенных вен нижней трети пищевода и желудка. На основе зарубежного опыта проанализированы риски подобных хирургических вмешательств и, основываясь на успешном клиническом наблюдении, предлагается оптимальная концепция хирургического лечения больных данной категории.Заключение. Мультидисциплинарный подход в условиях многопрофильной клиники позволяет обеспечить адекватное лечение больных раком прямой кишки, сочетающимся с портальной гипертензией и циррозом печени.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of publication</title><p>The aim of publication. To estimate efficacy of multidisciplinary approach in treatment of patients with rectal cancer together with portal hypertension and liver cirrhosis using the example of clinical case.</p></sec><sec><title>Original positions</title><p>Original positions. 71 year-old male patient with diagnosed low rectal cancer and concomitant: decompensated liver cirrhosis, portal hypertension with varicose esophageal and stomach veins and hepatocellular failure of class C by Child-Pugh. Patient was treated by simultaneous abdomino-perineal rectal excision with para-aortic lymphadenectomy and retroperitoneal end colostomy, splenectomy, devascularization of the stomach, gastrotomy with stitching of varicose veins at the lower third of the esophagus and the stomach. On the basis of foreign experience, risks of such surgical interventions were analyzed and, based on current clinical case, optimal surgical concept for patients of this category is proposed.</p></sec><sec><title>Conclusion</title><p>Conclusion. Multidisciplinary approach in diversified clinic allows to provide adequate treatment of patients with cancer of the rectum combined with portal hypertension and liver cirrhosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рак прямой кишки</kwd><kwd>брюшно-промежностная экстирпация</kwd><kwd>портальная гипертензия</kwd><kwd>варикозно-расширенные вены пищевода и желудка</kwd><kwd>цирроз печени</kwd><kwd>мультидисциплинарный подход</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rectal cancer</kwd><kwd>abdomino-perineal excision</kwd><kwd>portal hypertension</kwd><kwd>varicose veins of the esophagus and the stomach</kwd><kwd>liver cirrhosis</kwd><kwd>multidisciplinary approach</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Садовникова И.И. Циррозы печени. Вопросы этиологии, патогенеза, клиники, диагностики, лечения // Рус. мед. журн. – 2003. – Т. 5, № 2. – С. 37–42.</mixed-citation><mixed-citation xml:lang="en">Садовникова И.И. Циррозы печени. Вопросы этиологии, патогенеза, клиники, диагностики, лечения // Рус. мед. журн. – 2003. – Т. 5, № 2. – С. 37–42.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Arroyo V., Jimenez W. Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem // J. Hepatol. – 2000. –Vol. 32, N 1 (suppl.). – P. 157–170.</mixed-citation><mixed-citation xml:lang="en">Arroyo V., Jimenez W. Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem // J. Hepatol. – 2000. –Vol. 32, N 1 (suppl.). – P. 157–170.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Barsky S.H., Gopalakrishna R. High metalloproteinase inhibitor content of human cirrhosis and its possible conference of metastasis resistance // J. Natl. Cancer Inst. – 1988. – Vol. 80, N 2. – P. 102–108.</mixed-citation><mixed-citation xml:lang="en">Barsky S.H., Gopalakrishna R. High metalloproteinase inhibitor content of human cirrhosis and its possible conference of metastasis resistance // J. Natl. Cancer Inst. – 1988. – Vol. 80, N 2. – P. 102–108.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Belghiti J. Chirurgieoesophagienne chez le cirrhotique // La chirurgie digestive chez le cirrhotique / Eds. Belghiti J., Gillet M. – Paris: Monographiesdel’AFC, 1993. –P. 61–72.</mixed-citation><mixed-citation xml:lang="en">Belghiti J. Chirurgieoesophagienne chez le cirrhotique // La chirurgie digestive chez le cirrhotique / Eds. Belghiti J., Gillet M. – Paris: Monographiesdel’AFC, 1993. –P. 61–72.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Blei A.T., Mazhar S., Davidson C.J. et al. Hemodynamic evaluation before liver transplantation: insights into the portal hypertensive syndrome // J. Clin. Gastroenterol. – 2007. – Vol. 41 (suppl. 3). – P. 323–329.</mixed-citation><mixed-citation xml:lang="en">Blei A.T., Mazhar S., Davidson C.J. et al. Hemodynamic evaluation before liver transplantation: insights into the portal hypertensive syndrome // J. Clin. Gastroenterol. – 2007. – Vol. 41 (suppl. 3). – P. 323–329.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Brown M.W., Burk R.F. Development of intractable ascites following upper abdominal surgery in patients with cirrhosis // Am. J. Med. – 1986. – Vol. 80, N 5. – P. 879–883.</mixed-citation><mixed-citation xml:lang="en">Brown M.W., Burk R.F. Development of intractable ascites following upper abdominal surgery in patients with cirrhosis // Am. J. Med. – 1986. – Vol. 80, N 5. – P. 879–883.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Del Olmo J.A., Flor-Lorente B., Flor-Civera B. et al. Risk factors for nonhepatic surgery in patients with cirrhosis // World J. Surg. – 2003. – Vol. 27, N 6. –P. 647–652.</mixed-citation><mixed-citation xml:lang="en">Del Olmo J.A., Flor-Lorente B., Flor-Civera B. et al. Risk factors for nonhepatic surgery in patients with cirrhosis // World J. Surg. – 2003. – Vol. 27, N 6. –P. 647–652.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Douard R., Lentschener C., Ozier Y., Dousset B.Operative risks of digestive surgery in cirrhotic patients // Gastroenterol. Clin. Biol. – 2009. – Vol. 33, N 6–7. – P. 555–564.</mixed-citation><mixed-citation xml:lang="en">Douard R., Lentschener C., Ozier Y., Dousset B.Operative risks of digestive surgery in cirrhotic patients // Gastroenterol. Clin. Biol. – 2009. – Vol. 33, N 6–7. – P. 555–564.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Gervaz P., Pak-art R., Nivatvongs S. et al. Colorectal adenocarcinoma in cirrhotic patients // J. Am. Coll. Surg. – 2003. – Vol. 196, N 6. – P. 874–879.</mixed-citation><mixed-citation xml:lang="en">Gervaz P., Pak-art R., Nivatvongs S. et al. Colorectal adenocarcinoma in cirrhotic patients // J. Am. Coll. Surg. – 2003. – Vol. 196, N 6. – P. 874–879.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Goldstein W.Z., EdogaJ., Crystal R. Management of colostomal hemorrhage resulting from portal hypertension // Dis. Colon Rectum. – 1980. – Vol. 23, N 2. –P. 86–90.</mixed-citation><mixed-citation xml:lang="en">Goldstein W.Z., EdogaJ., Crystal R. Management of colostomal hemorrhage resulting from portal hypertension // Dis. Colon Rectum. – 1980. – Vol. 23, N 2. –P. 86–90.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Jackson F.C., Christophersen E.B., Peternel W.W., Kirimli B. Preoperative management of patients with liver disease // Surg. Clin. North Am. – 1968. – Vol. 48, N 4. – P. 907–930.</mixed-citation><mixed-citation xml:lang="en">Jackson F.C., Christophersen E.B., Peternel W.W., Kirimli B. Preoperative management of patients with liver disease // Surg. Clin. North Am. – 1968. – Vol. 48, N 4. – P. 907–930.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kaufman B., Roccaforte J. Hepatic anatomy, function, and physiology // Clinical anesthesia, 6th ed. / Eds. Barash P.G., Cullen B.F., Stoelting R.K. et al. – Philadelphia: Lippincott Williams &amp; Wilkins, 2009. – P. 1247–1278.</mixed-citation><mixed-citation xml:lang="en">Kaufman B., Roccaforte J. Hepatic anatomy, function, and physiology // Clinical anesthesia, 6th ed. / Eds. Barash P.G., Cullen B.F., Stoelting R.K. et al. – Philadelphia: Lippincott Williams &amp; Wilkins, 2009. – P. 1247–1278.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen G.C., Correia A.J., Thuluvath P.J. The impact of cirrhosis and portal hypertension on mortality following colorectal surgery: a nationwide, population-based study // Dis. Colon Rectum. – 2009. – Vol. 52, N 8. – P. 1367–1374.</mixed-citation><mixed-citation xml:lang="en">Nguyen G.C., Correia A.J., Thuluvath P.J. The impact of cirrhosis and portal hypertension on mortality following colorectal surgery: a nationwide, population-based study // Dis. Colon Rectum. – 2009. – Vol. 52, N 8. – P. 1367–1374.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Noble J.A., Caces M.F., Steffens R.A., Stinson F.S. Cirrhosis hospitalization and mortality trends, 1970–87 // Public Health Rep. – 1993. – Vol. 108, N 2. – P. 192–197.</mixed-citation><mixed-citation xml:lang="en">Noble J.A., Caces M.F., Steffens R.A., Stinson F.S. Cirrhosis hospitalization and mortality trends, 1970–87 // Public Health Rep. – 1993. – Vol. 108, N 2. – P. 192–197.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Nonami T., Hirai A.,Takagi H. Surgical treatment for colorectal carcinoma combined with liver cirrhosis // Nippon Geka Gakkai Zasshi. – 1997. – Vol. 98, N 8. – P. 680–684.</mixed-citation><mixed-citation xml:lang="en">Nonami T., Hirai A.,Takagi H. Surgical treatment for colorectal carcinoma combined with liver cirrhosis // Nippon Geka Gakkai Zasshi. – 1997. – Vol. 98, N 8. – P. 680–684.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Northup P.G., Sundaram V., Fallon M.B. et al. Hypercoagulation and thrombophilia in liver disease // J. Thromb. Haemost. – 2008. – Vol. 6, N 1. – P. 2–9.</mixed-citation><mixed-citation xml:lang="en">Northup P.G., Sundaram V., Fallon M.B. et al. Hypercoagulation and thrombophilia in liver disease // J. Thromb. Haemost. – 2008. – Vol. 6, N 1. – P. 2–9.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">O’Connor C., Rothenberg D., Tuman K. Anesthesia and the hepatobiliary system // Anesthesia, 6th ed. / Ed. Miller R.D. – Philadelphia: Churchill Livingstone, 2005. – P. 2209–2230.</mixed-citation><mixed-citation xml:lang="en">O’Connor C., Rothenberg D., Tuman K. Anesthesia and the hepatobiliary system // Anesthesia, 6th ed. / Ed. Miller R.D. – Philadelphia: Churchill Livingstone, 2005. – P. 2209–2230.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Pugh R.N., Murray-Lyon I.M., Dawson J.L. et al. Transection of the oesophagus for bleeding</mixed-citation><mixed-citation xml:lang="en">Pugh R.N., Murray-Lyon I.M., Dawson J.L. et al. Transection of the oesophagus for bleeding</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">oesophagealvarices // Br. J. Surg. – 1973. – Vol. 60, N 8. – P. 646–649.</mixed-citation><mixed-citation xml:lang="en">oesophagealvarices // Br. J. Surg. – 1973. – Vol. 60, N 8. – P. 646–649.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Valla D. Complications postoperatoires chez les maladesatteints de cirrhose // La chirurgie digestive chez le cirrhotique / Eds. Belghiti J., Gillet M. – Paris: Monographiesdel’AFC. – 1993. – P. 41–52.</mixed-citation><mixed-citation xml:lang="en">Valla D. Complications postoperatoires chez les maladesatteints de cirrhose // La chirurgie digestive chez le cirrhotique / Eds. Belghiti J., Gillet M. – Paris: Monographiesdel’AFC. – 1993. – P. 41–52.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Zarski J., Bichard P., Bourbon P. et al. La chirurgie digestive extrahepatique chez le cirrhotique: mortalite, morbidite, facteurspronostiquespreoperatoires // Gastroenterol. Clin. Biol. – 1988. – Vol. 12. – P. 43–47.</mixed-citation><mixed-citation xml:lang="en">Zarski J., Bichard P., Bourbon P. et al. La chirurgie digestive extrahepatique chez le cirrhotique: mortalite, morbidite, facteurspronostiquespreoperatoires // Gastroenterol. Clin. Biol. – 1988. – Vol. 12. – P. 43–47.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ziser A., Plevak D.J., Wiesner R.H. et al. Morbidity and mortality in cirrhotic patients undergoing anesthesia and surgery // Anesthesiology. – 1999. – Vol. 90, N 1. – P. 42–53.</mixed-citation><mixed-citation xml:lang="en">Ziser A., Plevak D.J., Wiesner R.H. et al. Morbidity and mortality in cirrhotic patients undergoing anesthesia and surgery // Anesthesiology. – 1999. – Vol. 90, N 1. – P. 42–53.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
