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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1527</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANG OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Кисломолочные бактерии: роль в регуляции кишечной перистальтики</article-title><trans-title-group xml:lang="en"><trans-title>Fermented-milk bacteria: role in intestinal peristalsis regulation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шульпекова</surname><given-names>Ю. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Shulpekova</surname><given-names>Yu. O.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2010</year></pub-date><volume>20</volume><issue>3</issue><fpage>68</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шульпекова Ю.О., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Шульпекова Ю.О.</copyright-holder><copyright-holder xml:lang="en">Shulpekova Y.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1527">https://www.gastro-j.ru/jour/article/view/1527</self-uri><abstract><p>Цель обзора. Показать роль кисломолочных бактерий, прежде всего родов Lactobacillus, Bifidumbacterium, и продуктов их метаболизма – короткоцепочечных жирных кислот в регуляции перистальтики кишечника.Основные положения. В клинических исследованиях изучено влияние пробиотических штаммов на выраженность симптомов функциональных кишечных расстройств. Наибольшее внимание уделено рассмотрению эффектов штамма Bifidobacterium animalis DN-173 010 (коммерческое название ActiRegularis). Установлено, что пробиотики, содержащие различные штаммы лакто- и бифидобактерий, оказывают мягкое слабительное действие без существенных нежелательных явлений и уменьшают дискомфорт в животе.Заключение. Продукт, содержащий штамм Bifidobacterium animalis DN-173 010 (с коммерческим названием ActiRegularis) эффективен в лечебных и профилактических целях для коррекции частоты и улучшения консистенции стула, уменьшения вздутия живота как при функциональных кишечных расстройствах, так и у практически здоровых людей.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of review</title><p>The aim of review. To demonstrate a role of fermented-milk bacteria, first of all Lactobacillus and Bifidumbacterium geni, and their metabolic products – short-chain fatty acids in regulation of peristalsis of the bowel.</p></sec><sec><title>Original positions</title><p>Original positions. In clinical studies the effect of probiotic strains on severity of symptoms of functional bowel disorders is investigated. The greatest attention is given to the effects of Bifidobacterium animalis DN-173 010 strain (commercial name — ActiRegularis). It was found out, that probiotics containing various strains of Lacto- and Bifidobacteria, have mild purging action without the essential undesirable effects and reduce abdominal dyscomfort.</p></sec><sec><title>Conclusion</title><p>Conclusion. The product containing Bifidobacterium animalis DN-173 010 strain (commercial name — ActiRegularis) is effective for medical and preventive purposes for correction of frequency and improvement of stool consistence, decrease of abdominal distention both at functional bowel disorders, and at practically healthy people.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>пробиотики</kwd><kwd>синдром раздраженного кишечника</kwd><kwd>запор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>probiotics</kwd><kwd>irritable bowel syndrome</kwd><kwd>constipation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Agrawal A., Houghton L.A., Morris J. et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation // Aliment. Pharmacol. Ther. – 2008 Sep 17 [Epub. ahead of print].</mixed-citation><mixed-citation xml:lang="en">Agrawal A., Houghton L.A., Morris J. et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation // Aliment. Pharmacol. Ther. – 2008 Sep 17 [Epub. ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Amenta M., Cascio M.T., Di Fiore P., Venturini I. Diet and chronic constipation. Benefits of oral supplementation with symbiotic zir fos (Bifidobacterium longum W11 + FOS Actilight) // Acta Biomed. – 2006. – Vol. 77, N 3. – P. 157–162.</mixed-citation><mixed-citation xml:lang="en">Amenta M., Cascio M.T., Di Fiore P., Venturini I. Diet and chronic constipation. Benefits of oral supplementation with symbiotic zir fos (Bifidobacterium longum W11 + FOS Actilight) // Acta Biomed. – 2006. – Vol. 77, N 3. – P. 157–162.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bekkali N.L., Bongers M.E., van den Berg M.M. et al. The role of a probiotics mixture in the treatment of childhood constipation: a pilot study // Nutr. J. – 2007. – Vol. 4, N 6. – P. 17.</mixed-citation><mixed-citation xml:lang="en">Bekkali N.L., Bongers M.E., van den Berg M.M. et al. The role of a probiotics mixture in the treatment of childhood constipation: a pilot study // Nutr. J. – 2007. – Vol. 4, N 6. – P. 17.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bixquert Jimйnez M. Treatment of irritable bowel syndrome with probiotics. An etiopathogenic approach at last? // Rev. Esp. Enferm. Dig. – 2009. – Vol. 101, N 8. – P. 553–564.</mixed-citation><mixed-citation xml:lang="en">Bixquert Jimйnez M. Treatment of irritable bowel syndrome with probiotics. An etiopathogenic approach at last? // Rev. Esp. Enferm. Dig. – 2009. – Vol. 101, N 8. – P. 553–564.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Cherbut C. Effects of short-chain fatty acids on gastrointestinal motility // Physiological and clinical aspects of short-chain fatty acids / Eds. J.H. Cummings, J.L. Rombeau, T. Sakata. – UK: Cambridge, Cambridge Univ. Press, 1995. – P. 191.</mixed-citation><mixed-citation xml:lang="en">Cherbut C. Effects of short-chain fatty acids on gastrointestinal motility // Physiological and clinical aspects of short-chain fatty acids / Eds. J.H. Cummings, J.L. Rombeau, T. Sakata. – UK: Cambridge, Cambridge Univ. Press, 1995. – P. 191.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chmielewska A., Szajewska H. Systematic review of randomised controlled trials: probiotics for functional constipation // World J. Gastroenterol. 2010. – Vol. 16, N 1. – P. 69–75.</mixed-citation><mixed-citation xml:lang="en">Chmielewska A., Szajewska H. Systematic review of randomised controlled trials: probiotics for functional constipation // World J. Gastroenterol. 2010. – Vol. 16, N 1. – P. 69–75.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">De Paula J.A., Carmuega E., Weill R. Effect of the ingestion of a symbiotic yogurt on the bowel habits of women with functional constipation // Acta Gastroenterol. Latinoam. – 2008. – Vol. 38, N 1. – P. 16–25.</mixed-citation><mixed-citation xml:lang="en">De Paula J.A., Carmuega E., Weill R. Effect of the ingestion of a symbiotic yogurt on the bowel habits of women with functional constipation // Acta Gastroenterol. Latinoam. – 2008. – Vol. 38, N 1. – P. 16–25.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Drouault-Holowacz S., Bieuvelet S., Burckel A. et al. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome // Gastroenterol. Clin. Biol. – 2008. – Vol. 32, N 2. – P. 147–152.</mixed-citation><mixed-citation xml:lang="en">Drouault-Holowacz S., Bieuvelet S., Burckel A. et al. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome // Gastroenterol. Clin. Biol. – 2008. – Vol. 32, N 2. – P. 147–152.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Duez H., Pelletier C., Cools S. et al. A colony immunoblotting method for quantitative detection of a Bifidobacterium animalis probiotic strain in human faeces // J. Appl. Microbiol. – 2000. – Vol. 88, N 6.</mixed-citation><mixed-citation xml:lang="en">Duez H., Pelletier C., Cools S. et al. A colony immunoblotting method for quantitative detection of a Bifidobacterium animalis probiotic strain in human faeces // J. Appl. Microbiol. – 2000. – Vol. 88, N 6.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">– P. 1019–1027.</mixed-citation><mixed-citation xml:lang="en">– P. 1019–1027.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Guyonnet D., Chassany O., Ducrotte P. et al. Effect of a fermented milk containing Bifidobacterium animalis</mixed-citation><mixed-citation xml:lang="en">Guyonnet D., Chassany O., Ducrotte P. et al. Effect of a fermented milk containing Bifidobacterium animalis</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
