gastro-jРоссийский журнал гастроэнтерологии, гепатологии, колопроктологииRussian Journal of Gastroenterology, Hepatology, Coloproctology1382-43762658-6673«Gastro» LLCgastro-j-1542Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL ARTICLESСовременные возможности подготовки кишечника к эндоскопическому исследованию в педиатрической практикеModern potential of preparation of intestine to endoscopy in pediatric practiceЭрдесС. И.ErdesS. I.ЛеоневскаяН. М.LeonevskayaN. M.ЛохматовМ. М.LokhmatovM. M.РатниковаМ. А.RatnikovaM. A.БудкинаТ. Н.BudkinaT. N.Первый Московский государственный медицинский университет им. И.М. СеченоваRussian Federation2010300820102043643Copyright © Эрдес С.И., Леоневская Н.М., Лохматов М.М., Ратникова М.А., Будкина Т.Н., 20102010Эрдес С.И., Леоневская Н.М., Лохматов М.М., Ратникова М.А., Будкина Т.Н.Erdes S.I., Leonevskaya N.M., Lokhmatov M.M., Ratnikova M.A., Budkina T.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gastro-j.ru/jour/article/view/1542

Цель исследования. Изучить эффективность и безопасность раствора фосфата натрия (Флит® Фосфо-сода) в качестве средства для подготовки кишечника перед эндоскопическим исследованием.Материал и методы. В исследование вошли 28 подростков 13–17 лет (средний возраст 14,96±1,05 года). Критерием включения в исследование явилась необходимость подготовки кишечника перед эндоскопическим исследованием. Критериями исключения были: частичная/полная кишечная непроходимость, мегаколон (врожденный/приобретенный), острые воспалительные заболевания и нарушение целостности толстой кишки, почечная/сердечная недостаточность. Оценивались: общее состояние пациента, динамика клинических проявлений, качество подготовки кишечника (возможность визуализации, наличие каловых масс), время наступления кишечной активности (появление стула), динамика гемодинамических показателей.Результаты. У 89,3% детей была достигнута хорошая визуализация кишечника. Переносимость препарата расценена как хорошая у 46,4%, как удовлетворительная у 53,6% пациентов. Побочные эффекты (тошнота, головокружение, вздутие живота и другие) носили кратковременный, быстропроходящий характер. Гемодинамические показатели не претерпели статистически значимых изменений.Заключение. Раствор фосфата натрия (Флит® Фосфо-сода) является эффективным препаратом для подготовки кишечника к эндоскопическим исследованиям, так как обеспечивает хорошую визуализацию слизистой оболочки и обладает малым количеством побочных эффектов. Его использование в педиатрической практике обеспечивает лучшую по сравнению с другими схемами приверженность к лечению, поскольку не требует приема большого объема жидкости.

Aim of investigation

Aim of investigation. To study efficacy and safety of sodium phosphate solution (Fleet® phospho-soda) as an agent for preparation of intestine to endoscopic investigation.

Material and methods

Material and methods. Overall 28 teenagers aged 13–17 years were enrolled to original study (mean age 14,96±1,05 year). Study inclusion criterion was the necessity of preparation of intestine before endoscopy. Exclusion criteria were: incomplete/complete ileus, megacolon (congenital/acquired), acute inflammatory diseases and disorder of large intestine integrity, renal/ heart failure. Estimated parameters included: general state of the patient, dynamics of clinical manifestations, quality of preparation of intestine (visualization capability, presence of fecal masses), time of bowel movement (development of stool), changes of hemodynamic scores.

Results

Results. In 89,3% of children good visualization of intestine has been achieved. Tolerability of agent was regarded as good in 46,4%, in 53,6% of patients – as satisfactory. Side effects (nausea, dizziness, flatulence etc.) were short-term and transient. Hemodynamic parameters did not undergo statistically significant changes.

Conclusion

Conclusion. Solution of sodium phosphate (FLEET® phospho-soda) is an efficient agent for preparation of intestine for endoscopic investigations as it provides good visualization of mucosa and has few side effects. Its application in pediatric practice provides the best compliance, as compared to other modes, because it does not require intake of high volume of fluid.

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The authors declare that there are no conflicts of interest present.