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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-1624</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Распространенность Helicobacter pylori и ГЭРБ у монголоидов и европеоидов Восточной Сибири</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of Helicobacter pylori and GERD at Mongoloids and Caucasians of Eastern Siberia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цуканов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsukanov</surname><given-names>V. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хоменко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khomenko</surname><given-names>O. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ржавичева</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Rzhavicheva</surname><given-names>O. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буторин</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Butorin</surname><given-names>N. N.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Штыгашева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shtygasheva</surname><given-names>O. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маады</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Maady</surname><given-names>A. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бичурина</surname><given-names>Т. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Bichurina</surname><given-names>T. B.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амельчугова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Amelchugova</surname><given-names>O. S.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>05</day><month>06</month><year>2009</year></pub-date><volume>19</volume><issue>3</issue><fpage>38</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Цуканов В.В., Хоменко О.В., Ржавичева О.С., Буторин Н.Н., Штыгашева О.В., Маады А.С., Бичурина Т.Б., Амельчугова О.С., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Цуканов В.В., Хоменко О.В., Ржавичева О.С., Буторин Н.Н., Штыгашева О.В., Маады А.С., Бичурина Т.Б., Амельчугова О.С.</copyright-holder><copyright-holder xml:lang="en">Tsukanov V.V., Khomenko O.V., Rzhavicheva O.S., Butorin N.N., Shtygasheva O.V., Maady A.S., Bichurina T.B., Amelchugova O.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/1624">https://www.gastro-j.ru/jour/article/view/1624</self-uri><abstract><p>Цель исследования. Изучить распространенность Helicobacter pylori и гастроэзофагеальной рефлюксной болезни (ГЭРБ) у различных этнических групп монголоидов и европеоидов Восточной Сибири.Материал и методы. Одномоментным (поперечным) методом была исследована распространенность H. pylori и ГЭРБ в Эвенкии, Хакасии и Тыве. Частота изжоги изучена у 6678 европеоидов, 1445 эвенков, 2085 хакасов и 572 тувинцев сплошным методом. Эзофагогастродуоденоскопия с забором биоптатов проведена в этих группах соответственно у 2125, 791, 630 и 250 человек. H. pylori определяли морфологическим, уреазным и иммуноферментным методом в сыворотке крови у 1492, 493, 533 и 414 обследованных.Результаты. Распространенность еженедельной изжоги составила у эвенков 6,4%, у хакасов – 10,3%, у тувинцев – 12,9%, у европеоидов – 12,3% (p1–3&lt;0,001, p1–4&lt;0,001). Эзофагит диагностирован у 5,4% европеоидов, у 0,6% эвенков, у 3,6% хакасов, у 5,1% тувинцев (р1–2&lt;0,001, р2–4&lt;0,001). Частота выявления H. pylori во всех популяциях была одинакова – около 90%.Выводы. Зарегистрированы отличия в распространенности ГЭРБ как между европеоидами и коренными жителями, так и между различными этническими группами монголоидов. Среди европеоидов и монголоидов Восточной Сибири отсутствует ассоциация между инфекцией H. pylori и ГЭРБ.</p></abstract><trans-abstract xml:lang="en"><sec><title>Aim of investigation</title><p>Aim of investigation. To study the prevalence Helicobacter pylori and gastroesophageal reflux disease (GERD) at various ethnic groups of Mongoloids and Caucasians of Eastern Siberia.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. Prevalence of H. pylori infection and GERD in Evenkia, Khakasia and Tuva had been studied by simultaneous (transverse) method. Frequency of heartburn was studied at 6678 Caucasians, 1445 Evenks, 2085 Khakases and 572 Tuvinians by continuous method. Esophagogastroduodenoscopy with biopsy sampling was carried out in these groups in 2125, 791, 630 and 250 patients respectively. H. pylori was determined by morphological, urease and immunoenzyme method in blood serum at 1492, 493, 533 and 414 subjects. Results. Prevalence of weekly heartburn was 6,4% in Evenks, 10,3% – in Khakases –, 12,9% – in Tuvinians, 12,3% – in Caucasians – (р1–3 &lt; 0,001, р1–4&lt; 0,001). Esophagitis is diagnosed in 5,4% of Caucasians, in 0,6% of Evenks, in 3,6% of Khakases, in 5,1% of Tuvinians (р 1–2&lt; 0,001, р2–4&lt; 0,001). Frequency of H. pylori infection in all populations was identical – about 90%.</p></sec><sec><title>Conclusions</title><p>Conclusions. Differences in prevalence of GERD were registered both between Caucasians and local population, and between various ethnic groups of Mongoloids. Between Caucasians and Mongoloids of Eastern Siberia there is no association between H. pylori infection and GERD.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ГЭРБ</kwd><kwd>Helicobacter pylori</kwd><kwd>изжога</kwd></kwd-group><kwd-group xml:lang="en"><kwd>GERD</kwd><kwd>Helicobacter pylori</kwd><kwd>heartburn</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лапина Т.Л. Основные принципы диагностики Helicobacter pylori // Рос. журн. гастроэнтерол. гепатол. колопроктол. – 1999. – Т. 9, № 2. – С. 41–45.</mixed-citation><mixed-citation xml:lang="en">Лапина Т.Л. 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