gastro-jРоссийский журнал гастроэнтерологии, гепатологии, колопроктологииRussian Journal of Gastroenterology, Hepatology, Coloproctology1382-43762658-6673«Gastro» LLCgastro-j-1739Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL ARTICLESКлинические аспекты функциональной диспепсии и эффективность ганатона (итоприда гидрохлорида) в ее леченииClinical aspects of functional dyspepsia and efficacy of ganaton (itopride hydrochloride)ИвашкинВ. Т.IvashkinV. T.ШептулинА. А.SheptulinA. A.ТрухмановА. С.TrukhmanovA. S.2009181220091961722Copyright © Ивашкин В.Т., Шептулин А.А., Трухманов А.С., 20092009Ивашкин В.Т., Шептулин А.А., Трухманов А.С.Ivashkin V.T., Sheptulin A.A., Trukhmanov A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gastro-j.ru/jour/article/view/1739

Цель исследования. Изучение особенностей клинической картины функциональной диспепсии (ФД) и эффективности применения ганатона (ито­прида гидрохлорида) в ее лечении.Материал и методы. Обследовано 509 больных ФД. До и после 4-­недельного курса ганатона (ито­прида гидрохлорида), назначавшегося в дозе 50 мг 3 раза в сутки, оценивалась выраженность клинических симптомов по 4­-балльной системе.Результаты. Отмечена высокая частота сочетания ФД с тошнотой, симптомами гастроэзофагеальной рефлюксной болезни (изжога) и синдромом раздраженного кишечника (метеоризм, расстрой­ства дефекации). Применение ганатона способствовало исчезновению жалоб у 46,6% больных, значительному уменьшению их выраженности – у 47,8%.Выводы. Ганатон является эффективным препаратом в лечении ФД и сопутствующих функциональных расстройств желудочно­кишечного тракта.

Aim of investigation

Aim of investigation. Studying of clinical pattern of functional dyspepsia (FD) and efficacy of ganaton (itopride hydrochloride) in its treatment.

Material and methods

Material and methods. Overall 509 patients with FD were investigated. Before and after 4-week course of ganaton (itopride hydrochloride) 50 mg tid, severity of clinical symptoms was estimated by 4-point system.

Results

Results. High frequency of combination of FD to nausea, symptoms of gastroesophageal reflux disease (heartburn) and irritable bowel syndromes (meteorism, disorders of defecation) was marked. Application of ganaton promoted relief of complaints in 46,6% of patients, significant decrease of their severity – at 47,8%.

Conclusions

Conclusions. Ganaton is efficient agent in treatment of FD and concomitant functional disorders of gastro-intestinal tract.

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The authors declare that there are no conflicts of interest present.