gastro-jРоссийский журнал гастроэнтерологии, гепатологии, колопроктологииRussian Journal of Gastroenterology, Hepatology, Coloproctology1382-43762658-6673«Gastro» LLCgastro-j-1877Research ArticleЛЕКЦИИ И ОБЗОРЫLECTURES AND REVIEWSГепатопульмональный синдром: диагностика, патогенез, клиническая симптоматика и способы леченияHepatopulmonary syndrome: diagnostics, pathogenesis, clinical symptomatology and methods of treatmentИвашкинВ. Т.IvashkinV. T.МорозоваМ. А.MorozovaM. A.МаевскаяМ. В.MaevskayaM. V.2008240420081821217Copyright © Ивашкин В.Т., Морозова М.А., Маевская М.В., 20082008Ивашкин В.Т., Морозова М.А., Маевская М.В.Ivashkin V.T., Morozova M.A., Maevskaya M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gastro-j.ru/jour/article/view/1877

Цель обзора. Проанализировать данные литературы по вопросам, связанным с определением гепатопульмонального синдрома (ГПС), его диагностикой, патогенезом, особенностями клинической картины и возможными способами лечения.Последние данные литературы. ГПС – это осложнение заболеваний печени, ведущее к нарушению перфузии легких и снижению оксигенации крови. Для распознавания этого синдрома необходимо наличие триады признаков: хроническое заболевание печени, расширение внутрилегочных сосудов, снижение оксигенации артериальной крови. На сегодняшний день представления исследователей о причинах и патогенезе расширения сосудов легких и нарушения газового состава крови при ГПС различаются.Заключение. До настоящего времени не разработаны четкий алгоритм диагностики данного состояния и тактика лечения больных с ГПС.

The aim of review

The aim of review. To analyze literature data on definition of hepatopulmonary syndrome (HPS), its diagnostics, pathogenesis, features of clinical presentation and treatment options.

Recent literature data

Recent literature data. HPS is complication of liver diseases, leading to disorders of perfusion in lungs and decrease of blood oxygenation. Diagnostics of this syndrome requires triad of signs: chronic liver disease, dilation of intrapulmonic vessels, decrease of arterial blood oxygenation. For the present time the concepts of causes and pathogenesis of pulmonary vasodilatation and disorders of blood gases composition at HPS are still inconsistent.

Conclusion

Conclusion. Up to now the definite algorithm of diagnostics and management of patients with HPS is not developed.

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The authors declare that there are no conflicts of interest present.