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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2016-26-1-107-115</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-27</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANG OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Морфологические и эндоскопические критерии диагностики зубчатых аденом толстой кишки</article-title><trans-title-group xml:lang="en"><trans-title>Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нечипай</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nechipay</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зобнина</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zobnina</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">dudka-m@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черкасова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Cherkasova</surname><given-names>L. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перфильев</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Perfilyev</surname><given-names>I. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривопусков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivopuskov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ «Поликлиника № 1» Управления делами Президента РФ, Москва, Российская Федерация ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава РФ, Москва, Российская Федерация; ГБУЗ «Городская клиническая больница № 57», Москва, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Federal government-financed institution «Polyclinic # 1», General affairs departments of the President of the Russian Federation, Moscow, the Russian Federation State educational state-funded institution «Russian medical academy of postgraduate education», Ministry of healthcare of the Russian Federation, Moscow, the Russian Federation; Federal government-financed healthcare institution «City clinical hospital #57», Moscow, the Russian Federation Municipal Hospital № 57<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>12</day><month>08</month><year>2016</year></pub-date><volume>26</volume><issue>1</issue><fpage>107</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нечипай А.М., Зобнина М.В., Черкасова Л.М., Перфильев И.Б., Кривопусков В.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Нечипай А.М., Зобнина М.В., Черкасова Л.М., Перфильев И.Б., Кривопусков В.А.</copyright-holder><copyright-holder xml:lang="en">Nechipay A.M., Zobnina M.V., Cherkasova L.M., Perfilyev I.B., Krivopuskov V.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/27">https://www.gastro-j.ru/jour/article/view/27</self-uri><abstract><p>Цель обзора. Обобщить данные литературы об эндоскопической и морфологической диагностике зубчатых аденом толстой кишки. Основные положения. В 2010 г. ВОЗ был принят новый вариант гистологической классификации опухолей толстой кишки, согласно которому зубчатые новообразования выделены в отдельную группу предопухолевых изменений, наряду с аденомой толстой кишки. На сегодняшний день установлено, что гиперпластические полипы и другие представители из этой группы в 15-20% случаев являются предшественниками спорадического или бессимптомного колоректального рака, локализующегося преимущественно в проксимальных отделах толстой кишки и развивающегося по иному, зубчатому, пути. Диагностика таких образований как на микроскопическом, так и на макроскопическом уровнях до сих пор представляет значительные трудности в связи с отсутствием единой общепринятой номенклатуры, четких морфологических характеристик и эндоскопической семиотики. Заключение. Определение основных морфологических и эндоскопических критериев диагностики всех представителей группы зубчатых аденом позволит не только успешно их выявлять, но и дифференцировать с другими эпителиальными образованиями толстой кишки, что необходимо для выбора правильной тактики ведения пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The aim of review. To generalize literature data on endoscopic and morphological diagnostics of serrated adenomas of the colon. Key points. In 2010 a new variant of histological classification of colonic tumors have been accepted by WHO, according to which serrated neoplasms were defined as separate group of preneoplastic changes, along with colonic adenomas. At the present time hyperplastic polyps and other serrated neoplasms are considered to be precursor lesions for 15 to 20% of sporadic or asymptomatic colorectal cancers located mainly in proximal colon, that progress by specific serrated adenoma-related pathway. Diagnostics of such lesions both on microscopic and macroscopical levels is associated with significant difficulties due to absence of the uniform nomenclature, definite morphological features and endoscopic semiotics. Conclusion. Definition of main morphological and endoscopic diagnostic criteria of all types of serrated adenomas will provide successful diagnostics along with differentiation with other epithelial colonic lesions that is required for proper choice of management approach.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>зубчатые аденомы</kwd><kwd>эндоскопическая диагностика</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Seigel R., Naishadham D., Jemal A. Cancer statistics, 2013. A Cancer J Clin 2013; 63:11-30.</mixed-citation><mixed-citation xml:lang="en">Seigel R., Naishadham D., Jemal A. Cancer statistics, 2013. A Cancer J Clin 2013; 63:11-30.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Pathology and genetics of tumours of the digestive system (IARC WHO classification of tumours). World Health Organization; (October 2010).</mixed-citation><mixed-citation xml:lang="en">Pathology and genetics of tumours of the digestive system (IARC WHO classification of tumours). World Health Organization; (October 2010).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д., Старинский В.В., Петрова Г.В. Злокачественные новообразования в России в 2012 году (заболеваемость и смертность). ФГБУ «МНИОИ им. П.А. Герцена» Минздрава России, 2014.</mixed-citation><mixed-citation xml:lang="en">Каприн А.Д., Старинский В.В., Петрова Г.В. Злокачественные новообразования в России в 2012 году (заболеваемость и смертность). ФГБУ «МНИОИ им. П.А. Герцена» Минздрава России, 2014.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Заридзе Д.Г. Профилактика рака. М.: ИМА пресс, 2009.</mixed-citation><mixed-citation xml:lang="en">Заридзе Д.Г. Профилактика рака. М.: ИМА пресс, 2009.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61:759-67.</mixed-citation><mixed-citation xml:lang="en">Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61:759-67.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">American Cancer Society. Cancer facts and figures 20112013. Atlanta (Ga): American Cancer Society, 2011.</mixed-citation><mixed-citation xml:lang="en">American Cancer Society. Cancer facts and figures 20112013. Atlanta (Ga): American Cancer Society, 2011.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ferlay J., Shin H.R., Bray F., et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127:2893-917.</mixed-citation><mixed-citation xml:lang="en">Ferlay J., Shin H.R., Bray F., et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127:2893-917.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J.R. Large intestine. Histological typing of intestinal tumours. In: Jass J.R., Sobin L.H., eds. World Health Organization international histological classification of tumours, 2nd ed. Berlin: Springer-Verlag, 1989:30.</mixed-citation><mixed-citation xml:lang="en">Jass J.R. Large intestine. Histological typing of intestinal tumours. In: Jass J.R., Sobin L.H., eds. World Health Organization international histological classification of tumours, 2nd ed. Berlin: Springer-Verlag, 1989:30.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Muto T., Bussey H.J.R., Morson B.C.M. The evolution of cancer of the colon and rectum. Cancer 1975; 36:225170.</mixed-citation><mixed-citation xml:lang="en">Muto T., Bussey H.J.R., Morson B.C.M. The evolution of cancer of the colon and rectum. Cancer 1975; 36:225170.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J.R. Relation between metaplastic polyp and carcinoma of the colorectum. Lancet 1983; 1:28-30.</mixed-citation><mixed-citation xml:lang="en">Jass J.R. Relation between metaplastic polyp and carcinoma of the colorectum. Lancet 1983; 1:28-30.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J.R., Young J., Leggett B.A. Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum. Histopathology 2000; 37:295-301.</mixed-citation><mixed-citation xml:lang="en">Jass J.R., Young J., Leggett B.A. Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum. Histopathology 2000; 37:295-301.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J.R. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007; 50:113-30.</mixed-citation><mixed-citation xml:lang="en">Jass J.R. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007; 50:113-30.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Leggett B.A., Devereaux B., Biden K., et al. Hyperplastic polyposis: association with colorectal cancer. Am J Surg Pathol 2001; 25:177-84.</mixed-citation><mixed-citation xml:lang="en">Leggett B.A., Devereaux B., Biden K., et al. Hyperplastic polyposis: association with colorectal cancer. Am J Surg Pathol 2001; 25:177-84.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Orlowska J. Serrated lesions and hyperplastic (serrated) polyposis relationship with colorectal cancer: classification and surveillance recommendations. Gastrointest Endosc 2013; 77:6.</mixed-citation><mixed-citation xml:lang="en">Orlowska J. Serrated lesions and hyperplastic (serrated) polyposis relationship with colorectal cancer: classification and surveillance recommendations. Gastrointest Endosc 2013; 77:6.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Longacre T.A., Fenoglio-Preiser C.M. Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia. Am J Surg Pathol 1990; 14:524-37.</mixed-citation><mixed-citation xml:lang="en">Longacre T.A., Fenoglio-Preiser C.M. Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia. Am J Surg Pathol 1990; 14:524-37.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Matsumoto T., Mizuno M., Shimizu M., et al. Serrated adenoma of the colorectum: colonoscopic and histologic features. Gastrointest Endosc 1999; 49:732-42.</mixed-citation><mixed-citation xml:lang="en">Matsumoto T., Mizuno M., Shimizu M., et al. Serrated adenoma of the colorectum: colonoscopic and histologic features. Gastrointest Endosc 1999; 49:732-42.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bariol C., Hawkins N.J., Turner J.J., et al. Histopathological and clinical evaluation of serrated adenomas of the colon and rectum. Mod Pathol 2003; 16:417-23.</mixed-citation><mixed-citation xml:lang="en">Bariol C., Hawkins N.J., Turner J.J., et al. Histopathological and clinical evaluation of serrated adenomas of the colon and rectum. Mod Pathol 2003; 16:417-23.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J.R. Hyperplastic polyps and serrated adenomas of the colorectum. Histopathology 2002; 41(Suppl. 2):367-71.</mixed-citation><mixed-citation xml:lang="en">Jass J.R. Hyperplastic polyps and serrated adenomas of the colorectum. Histopathology 2002; 41(Suppl. 2):367-71.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Rex D.K., Ahnen D.J., Baron J.A., et al. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol 2012; 107:131528.</mixed-citation><mixed-citation xml:lang="en">Rex D.K., Ahnen D.J., Baron J.A., et al. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol 2012; 107:131528.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Jass J.R. Serrated adenoma of the colorectum. Curr Diagn Pathol 2002; 8:42-9.</mixed-citation><mixed-citation xml:lang="en">Jass J.R. Serrated adenoma of the colorectum. Curr Diagn Pathol 2002; 8:42-9.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Fogt F., Brien T., Brown C.A., et al. Genetic alterations in serrated adenomas. Comparison to conventional adenomas and hyperplastic polyps. Hum Pathol 2002; 33:87-91.</mixed-citation><mixed-citation xml:lang="en">Fogt F., Brien T., Brown C.A., et al. Genetic alterations in serrated adenomas. Comparison to conventional adenomas and hyperplastic polyps. Hum Pathol 2002; 33:87-91.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Iwabuchi M., Sasano H., Hiwatashi N., et al. Serrated adenoma: a clinicopathological, DNA ploidy and immunohistochemical study. Anticancer Res 2000; 20:1141-7.</mixed-citation><mixed-citation xml:lang="en">Iwabuchi M., Sasano H., Hiwatashi N., et al. Serrated adenoma: a clinicopathological, DNA ploidy and immunohistochemical study. Anticancer Res 2000; 20:1141-7.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Snover D.C. Update on the serrated pathway to colorectal carcinoma. Hum Pathol 2011; 42:1-10.</mixed-citation><mixed-citation xml:lang="en">Snover D.C. Update on the serrated pathway to colorectal carcinoma. Hum Pathol 2011; 42:1-10.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Wallace M., Kiesslich R. Advances in endoscopic imaging of colorectal Neoplasia. Gastroenterology 2010; 138:2140-50.</mixed-citation><mixed-citation xml:lang="en">Wallace M., Kiesslich R. Advances in endoscopic imaging of colorectal Neoplasia. Gastroenterology 2010; 138:2140-50.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Kimura T., Yamamoto E., Yamano H., et. al. A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma. Am J Gastroenterol 2012; 107:460-9.</mixed-citation><mixed-citation xml:lang="en">Kimura T., Yamamoto E., Yamano H., et. al. A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma. Am J Gastroenterol 2012; 107:460-9.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Torlakovic E., Skovland E., Snover D.C., et al. Morphologic reappraisal of serrated colorectal polyps. Am J Surg Pathol 2003; 27:65-81.</mixed-citation><mixed-citation xml:lang="en">Torlakovic E., Skovland E., Snover D.C., et al. Morphologic reappraisal of serrated colorectal polyps. Am J Surg Pathol 2003; 27:65-81.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Berkeley N., Dora Lam-Himlin, Arnold M.A., et al. The cutting edge of serrated polyps: a practical guide to approaching and managing serrated colon polyps. Gastrointest Endosc 2013; 77:3.</mixed-citation><mixed-citation xml:lang="en">Berkeley N., Dora Lam-Himlin, Arnold M.A., et al. The cutting edge of serrated polyps: a practical guide to approaching and managing serrated colon polyps. Gastrointest Endosc 2013; 77:3.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Rex D.K, Ahnen D.J., Baron J.A., et al. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol 2012; 107:1315-29, quiz 1314.</mixed-citation><mixed-citation xml:lang="en">Rex D.K, Ahnen D.J., Baron J.A., et al. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol 2012; 107:1315-29, quiz 1314.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Kudo S., Tamura S., Nakajima T., et al. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 1996; 44:8-14.</mixed-citation><mixed-citation xml:lang="en">Kudo S., Tamura S., Nakajima T., et al. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 1996; 44:8-14.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Kudo S., Lambert R., Allen J.I., et al. Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc 2008; 68:4.</mixed-citation><mixed-citation xml:lang="en">Kudo S., Lambert R., Allen J.I., et al. Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc 2008; 68:4.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Hetzel J.T., Huang C.S., Coukos J.A., et al. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol 2010; 105:2656-64.</mixed-citation><mixed-citation xml:lang="en">Hetzel J.T., Huang C.S., Coukos J.A., et al. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol 2010; 105:2656-64.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Shrubsole M.J., Wu H., Ness R.M., et al. Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am J Epidemiol 2008; 167:1050-8.</mixed-citation><mixed-citation xml:lang="en">Shrubsole M.J., Wu H., Ness R.M., et al. Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am J Epidemiol 2008; 167:1050-8.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Tadepalli U.S., Feihel D., Miller K.M., et al. Amorphologic analysis of sessile serrated polyps observed during routine colonoscopy (with video). Gastrointest Endosc 2011; 74:1360-8.</mixed-citation><mixed-citation xml:lang="en">Tadepalli U.S., Feihel D., Miller K.M., et al. Amorphologic analysis of sessile serrated polyps observed during routine colonoscopy (with video). Gastrointest Endosc 2011; 74:1360-8.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Lu F.I., van Niekerk de W., Owen D., et al. Longitudinal outcome study of sessile serrated adenomas of the colorectum: an increased risk for subsequent right-sided colorectal carcinoma. Am J Surg Pathol 2010; 34:927-34.</mixed-citation><mixed-citation xml:lang="en">Lu F.I., van Niekerk de W., Owen D., et al. Longitudinal outcome study of sessile serrated adenomas of the colorectum: an increased risk for subsequent right-sided colorectal carcinoma. Am J Surg Pathol 2010; 34:927-34.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Hazewinkel Y., Lopez-Ceron M., East J.E., et al. Endoscopic features of sessile serrated adenomas: validation by international experts using high-resolution white-light endoscopy and narrow-band imaging. Gastrointest Endosc 2013; 77:916-24.</mixed-citation><mixed-citation xml:lang="en">Hazewinkel Y., Lopez-Ceron M., East J.E., et al. Endoscopic features of sessile serrated adenomas: validation by international experts using high-resolution white-light endoscopy and narrow-band imaging. Gastrointest Endosc 2013; 77:916-24.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Oka S., Tanaka S., Hiyama T., et al. Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types. Gastrointest Endosc 2004; 59:213-9.</mixed-citation><mixed-citation xml:lang="en">Oka S., Tanaka S., Hiyama T., et al. Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types. Gastrointest Endosc 2004; 59:213-9.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Kim K.M., Lee E.J. Kras mutations in traditional serrated adenomas from Korea herald an aggressive phenotype. Am J Surg Pathol 2010; 34:667-75.</mixed-citation><mixed-citation xml:lang="en">Kim K.M., Lee E.J. Kras mutations in traditional serrated adenomas from Korea herald an aggressive phenotype. Am J Surg Pathol 2010; 34:667-75.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Hassan С., Quintero E., Dumonceau J.M., et al. Post-polypectomy colonoscopy surveillance: European Society of gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2013; 45:841-51.</mixed-citation><mixed-citation xml:lang="en">Hassan С., Quintero E., Dumonceau J.M., et al. Post-polypectomy colonoscopy surveillance: European Society of gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2013; 45:841-51.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Wen-Hsin H., Meng-Shun S., Hoi-Wan L., et al. Colorectal Sessile serrated adenoma/polyp with dysplasia may lose typical mucous-cap appearance. Berlin: UEG Week, 2013.</mixed-citation><mixed-citation xml:lang="en">Wen-Hsin H., Meng-Shun S., Hoi-Wan L., et al. Colorectal Sessile serrated adenoma/polyp with dysplasia may lose typical mucous-cap appearance. Berlin: UEG Week, 2013.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
