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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2018-28-6-68-76</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-299</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАЦИОНАЛЬНАЯ ШКОЛА ГАСТРОЭНТЕРОЛОГИИ, ГЕПАТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NATIONAL COLLEGE OF GASTROENTEROLOGY, HEPATOLOGY</subject></subj-group></article-categories><title-group><article-title>Пациент с неконтролируемой отрыжкой: что делать?</article-title><trans-title-group xml:lang="en"><trans-title>A Patient with Uncontrollable Belching: What to Do?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maev</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, академик РАН, заведующий кафедрой пропедевтики внутренних болезней и гастроэнтерологии; заслуженный врач РФ, заслуженный деятель науки РФ.</p><p>127473, г. Москва, ул. Делегатская, д. 20, стр. 1.</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Prof., RAS Academician, Departmental Head, Department of Propaedeutics of Internal Diseases and Gastroenterology; Honored Doctor of the Russian Federation, Honored Scientist of the Russian Federation.</p><p>127473, Moscow, Delegatskaya str., 20, building 1.</p></bio><email xlink:type="simple">igormaev@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучерявый</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucheryaviy</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней и гастроэнтерологии; научный сотрудник лаборатории функциональных методов исследования в гастроэнтерологии.</p><p>127473, г. Москва, ул. Делегатская, д. 20, стр. 1.</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Ass. Prof., Department of Propaedeutics of Internal Diseases and Gastroenterology; Researcher, Laboratory of Functional Methods of Research in Gastroentherology.</p><p>127473, Moscow, Delegatskaya str., 20, building 1.</p></bio><email xlink:type="simple">proped@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баркалова</surname><given-names>E. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Barkalova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры пропедевтики внутренних болезней и гастроэнтерологии; руководитель лаборатории функциональных методов исследования в гастроэнтерологии.</p><p>127473, г. Москва, ул. Делегатская, д. 20, стр. 1.</p></bio><bio xml:lang="en"><p>Research Assistant, Department of Propaedeutics of Internal Diseases and Gastroenterology; Dentistry, Laboratory Head, Laboratory of Functional Methods of Research in Gastroentherology.</p><p>127473, Moscow, Delegatskaya str., 20, building 1.</p></bio><email xlink:type="simple">maslovaalena@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овсепян</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovsepyan</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший лаборант кафедры пропедевтики внутренних болезней и гастроэнтерологии; научный сотрудник лаборатории функциональных методов исследования в гастроэнтерологии.</p><p>127473, г. Москва, ул. Делегатская, д. 20, стр. 1.</p></bio><bio xml:lang="en"><p>Senior Researcher, Department of Propaedeutics of Internal Diseases and Gastroenterology; Researcher, Laboratory of Functional Methods of Research in Gastroentherology.</p><p>127473, Moscow, Delegatskaya str., 20, building 1.</p></bio><email xlink:type="simple">solnwshko_@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>17</day><month>01</month><year>2019</year></pub-date><volume>28</volume><issue>6</issue><fpage>68</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маев И.В., Кучерявый Ю.А., Баркалова E.В., Овсепян М.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Маев И.В., Кучерявый Ю.А., Баркалова E.В., Овсепян М.А.</copyright-holder><copyright-holder xml:lang="en">Maev I.V., Kucheryaviy Y.A., Barkalova E.V., Ovsepyan M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/299">https://www.gastro-j.ru/jour/article/view/299</self-uri><abstract><sec><title>Цель</title><p>Цель. Описать возможное клиническое значение отрыжки и представить клиническое наблюдение с описанием дифференциального диагноза отрыжки.</p></sec><sec><title>Основное содержание</title><p>Основное содержание. Отрыжка может быть явлением физиологическим или патологическим. Патологическая отрыжка требует адекватного диагностического подхода с целью уточнения природы ее возникновения. Гастральная отрыжка осуществляется рефлекторно при растяжении желудка избытком воздуха, попавшим при глотании, что инициирует преходящие расслабления нижнего пищеводного сфинктера и как следствие выход воздуха из желудка в пищевод, а затем в глотку. Супрагастральная отрыжка — это явление, при котором воздух, попадая в пищевод, не достигает желудка, а стремительно выходит обратно в глотку, при этом, в отличие от аэрофагии, попадание воздуха в пищевод не сопровождается актом глотания. Супрагастральная отрыжка — не рефлекторный процесс, рассматривается как проявление поведенческого расстройства. Суточная рН-импедансометрия и манометрия пищевода высокого разрешения высоко информативны для выявления различных типов отрыжки (гастральной и супрагастральной), а также механизмов их осуществления. Представлено клиническое наблюдение пациентки 47 лет с супрагастральной отрыжкой, которой назначена речевая терапия под контролем логопеда.</p></sec><sec><title>Заключение</title><p>Заключение. Суточная рН-импедансометрия и манометрия пищевода высокого разрешения (в том числе в комбинации с импедансометрией) позволяют провести полноценную дифференциальную диагностику отрыжки, что позволяет выбрать наиболее эффективную тактику ведения пациента.</p></sec></abstract><trans-abstract xml:lang="en"><p>Aim. In this paper, we discuss the clinical significance of belching and present a clinical case with the description of the belching differential diagnosis.Main findings. Belching may be either a physiological or a pathological phenomenon. Pathological belching requires an adequate diagnostic approach in order to clarify the nature of its occurrence. Gastric belching occurs reflexively at the moment of stomach stretching by excess air trapped during swallowing, which initiates the transient relaxation of the lower esophageal sphincter. As a consequence, the swallowed air escapes from the stomach first into the esophagus and then into the throat. Supragastric belching is a phenomenon, in which the air entering the esophagus does not reach the stomach, but rapidly returns to the throat. In this case, unlike aerophagia, the air entering the esophagus is not accompanied by the act of swallowing. Supragastric belching is not a reflex process; rather, it is considered to be a manifestation of behavioural disorders. 24-hour pH-impedancemetry and high-resolution esophageal manometry are highly informative methods for detecting various types of belching (gastric and supragastric), as well as their mechanisms. We present a clinical observation of a 47-year-old patient suffering from supragastric belching and treated by speech therapy under the supervision of a speech therapist. Conclusion. 24-hour pH-impedancemetry and high-resolution esophageal manometry (also in combination with impedancemetry) provide a complete differential diagnosis of belching and allow the most effective patient management strategy to be selected.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>супрагастральная отрыжка</kwd><kwd>поведенческое расстройство</kwd><kwd>рН-импедансометрия</kwd><kwd>манометрия высокого разрешения в комбинации с импедансометрией</kwd><kwd>речевая терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>supragastric belching</kwd><kwd>behavioural disorder</kwd><kwd>pH-impedancemetry</kwd><kwd>high-resolution manometry in combination with impedancemetry</kwd><kwd>speech therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bredenoord A.J., Weusten B.L., Timmer R. et al. Relationships between air swallowing, intragastric air, belching and gastro-oesophageal reflux. Neurogastroenterol Motil. 2005;17:341–7.</mixed-citation><mixed-citation xml:lang="en">Bredenoord A.J., Weusten B.L., Timmer R. et al. Relationships between air swallowing, intragastric air, belching and gastro-oesophageal reflux. Neurogastroenterol Motil. 2005;17:341–7.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т., Маев И.В., Трухманов А.С., Стороновa О.А. и др. Манометрия высокого разрешения и новая классификация нарушений моторики пищевода. Терапевтический архив. 2018;05:93–100.</mixed-citation><mixed-citation xml:lang="en">Ivashkin V.T., Maev I.V., Trukhmanov A.S., Storonova O.A. et al. High resolution manometry and the new classification of esophageal motility disorders. Therapeutic Archive. 2018;05:93–100 (In Rus.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ten Cate L., Herregots T.V.K., Dejonckere P.H., Hemmink G.J.M. et al. Speech therapy as treatment for supragastric belching. Dysphagia. 2018;33(5):707–15.</mixed-citation><mixed-citation xml:lang="en">Ten Cate L., Herregots T.V.K., Dejonckere P.H., Hemmink G.J.M. et al. Speech therapy as treatment for supragastric belching. Dysphagia. 2018;33(5):707–15.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kessing B.F., Bredenoord A.J., Smout A.J. Mechanisms of gastric and supragastric belching: a study using concurrent high-resolution manometry and impedance monitoring. Neurogastroenterol Motil. 2012;24(12):573–9.</mixed-citation><mixed-citation xml:lang="en">Kessing B.F., Bredenoord A.J., Smout A.J. Mechanisms of gastric and supragastric belching: a study using concurrent high-resolution manometry and impedance monitoring. Neurogastroenterol Motil. 2012;24(12):573–9.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chitkara D.K., Bredenoord A.J., Rucher M.J. et al. Aerophagia in adults: a comparison with functional dyspepsia. Aliment Pharmacol Ther. 2005;22:855–8.</mixed-citation><mixed-citation xml:lang="en">Chitkara D.K., Bredenoord A.J., Rucher M.J. et al. Aerophagia in adults: a comparison with functional dyspepsia. Aliment Pharmacol Ther. 2005;22:855–8.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Karamanolis G., Triantafyiiou K., Tsiamoulos Z. et al. Effect of sleep on excessive belching: a 24-hour impedancepH study. J Clin Gastroenterol. 2010;44:332–4.</mixed-citation><mixed-citation xml:lang="en">Karamanolis G., Triantafyiiou K., Tsiamoulos Z. et al. Effect of sleep on excessive belching: a 24-hour impedancepH study. J Clin Gastroenterol. 2010;44:332–4.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bredenoord A.J. Management of belching, hiccups, and aerophagia. Clin Gastroenterol Hepatol. 2013;11:6–12.</mixed-citation><mixed-citation xml:lang="en">Bredenoord A.J. Management of belching, hiccups, and aerophagia. Clin Gastroenterol Hepatol. 2013;11:6–12.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bredenoord A.J., Smout A. Physiologic and pathologic belching. Clin Gastroenterol Hepatol. 2007;5:772–5.</mixed-citation><mixed-citation xml:lang="en">Bredenoord A.J., Smout A. Physiologic and pathologic belching. Clin Gastroenterol Hepatol. 2007;5:772–5.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Roman S., Gyawali C.P., Savarino E. et al. Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: update of the Porto consensus and recommendations from an international consensus group. Neurogastroenterol Motil. 2017;29:1–15.</mixed-citation><mixed-citation xml:lang="en">Roman S., Gyawali C.P., Savarino E. et al. Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: update of the Porto consensus and recommendations from an international consensus group. Neurogastroenterol Motil. 2017;29:1–15.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Маев И.В., Баркалова Е.В., Овсепян М.А., Кучерявый Ю.А. и др. Возможности рН-импедансометрии и манометрии высокого разрешения при ведении пациентов с рефрактерной гастроэзофагеальной рефлюксной болезнью. Тер архив. 2017;89(2):76–83.</mixed-citation><mixed-citation xml:lang="en">Maev I.V., Barkalova E.V., Ovsepyan M.A., Kucheryavyy Yu.A. et al. Esophageal pHimpedance monitoring and high-resolution manometry in patients with various forms of gastroesophageal reflux disease. Therapeutic Archive. 2017;89(2):76–83 (In Rus.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kessing B.F., Bredenoord A.J., Smout A.J. The pathophysiology, diagnosis and treatmet of excessive belching symptoms. The Am J Gastroenterol. 2014;109(8):1196–203.</mixed-citation><mixed-citation xml:lang="en">Kessing B.F., Bredenoord A.J., Smout A.J. The pathophysiology, diagnosis and treatmet of excessive belching symptoms. The Am J Gastroenterol. 2014;109(8):1196–203.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Баркалова Е.В., Кучерявый Ю.А., Маев И.В. Манометрия высокого разрешения в диагностике нарушений двигательной функции пищевода. Мед Совет. 2018;(5):104–10.</mixed-citation><mixed-citation xml:lang="en">Barkalova E.V., Kucheryavyy Yu.A., Mayev I.V. High resolution manometry in the diagnosis of esophageal motility disorders. Medical Council. 2018;(5):104–10 (In Rus.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gyawali C.P. High resolution manometry: the Ray Clouse legacy. Neurogastroenterol Motil. 2012;24(Suppl 1):2–4.</mixed-citation><mixed-citation xml:lang="en">Gyawali C.P. High resolution manometry: the Ray Clouse legacy. Neurogastroenterol Motil. 2012;24(Suppl 1):2–4.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Rohof W.O.A., Bredenoord A.J. Chicago Classification of Esophageal Motility Disorders: Lessons Learned. Curr Gastroenterol Rep. 2017;19(8):37.</mixed-citation><mixed-citation xml:lang="en">Rohof W.O.A., Bredenoord A.J. Chicago Classification of Esophageal Motility Disorders: Lessons Learned. Curr Gastroenterol Rep. 2017;19(8):37.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Savarino E., de Bortoli N., Bellini M., Galeazzi F. et al. Practice guidelines on the use of esophageal manometry — A GISMAD-SIGE-AIGO medical position statement. Dig Liver Dis. 2016;48(10):1124–35.</mixed-citation><mixed-citation xml:lang="en">Savarino E., de Bortoli N., Bellini M., Galeazzi F. et al. Practice guidelines on the use of esophageal manometry — A GISMAD-SIGE-AIGO medical position statement. Dig Liver Dis. 2016;48(10):1124–35.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Маев И.В., Баркалова Е.В., Овсепян М.А., Кучерявый Ю.А. и др. Манометрия пищевода высокого разрешения в клинической практике. Клин Мед. 2017;95(12):1127–37.</mixed-citation><mixed-citation xml:lang="en">Maev I.V., Barkalova E.V., Ovsepyan M.A., Kucheryavyi Yu.A. et al. High resolution esophageal manometry in clinical practice. Clinical Medicine (Russian Journal). 2017;95(12):1127–37 (In Rus.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kahrilas P., Bredenoord A., Fox M., Gyawali C. et al. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol. Motil. 2015;27:160–74.</mixed-citation><mixed-citation xml:lang="en">Kahrilas P., Bredenoord A., Fox M., Gyawali C. et al. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol. Motil. 2015;27:160–74.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Glasinovic E., Wynter E., Arguero J., Ooi J. et al. Treatment of supragastric belching with cognitive behavioral therapy improves quality of life and reduces acid gastroesophageal reflux. Am J Gastroenterol. 2018;113(4):539–47.</mixed-citation><mixed-citation xml:lang="en">Glasinovic E., Wynter E., Arguero J., Ooi J. et al. Treatment of supragastric belching with cognitive behavioral therapy improves quality of life and reduces acid gastroesophageal reflux. Am J Gastroenterol. 2018;113(4):539–47.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
