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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2019-29-1-31-35</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-324</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Возможности применения фибринового клея при лечении свищей прямой кишки</article-title><trans-title-group xml:lang="en"><trans-title>Application of Fibrin Glue in the Treatment of Rectal Fistula</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4697-2839</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Frolov</surname><given-names>Sergey A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, лауреат Премии Правительства РФ в области науки и техники, заместитель директора по научной работе </p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Prof., Winner of the Prize of the Russian Federation Government in the Field of Science and Technology, Deputy director</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">info@gnck.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7544-4752</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьминов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzminov</surname><given-names>Alexandr M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, руководитель отдела общей колопроктологии с группой изучения семейного аденоматоза толстой кишки </p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Prof., Departmental Head, Department of General Coloproctology with a Group for Studying the Familial adenomatous Polyposis</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">9249591@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вышегородцев</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyshegorodtsev</surname><given-names>Dmitry V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, старший научный сотрудник отдела общей проктологии с группой изучения семейного аденоматоза</p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Senior Researcher, Department of General Coloproctology with a Group for Studying the Familial adenomatous Polyposis</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">vyshegorodtsev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2619-5929</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королик</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolik</surname><given-names>Vyacheslav Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, научный сотрудник отдела общей проктологии с груп-пой изучения семейного аденоматоза</p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Researcher, Department of General Coloproctology with a Group for Studying the Familial Adenomatous Polyposis</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">v.korolik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минбаев</surname><given-names>Ш. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Minbaev</surname><given-names>Sharof T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, врач отделения общей проктологии с группой изучения семейного аденоматоза</p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Doctor, Department of General Coloproctology with a Group for Studying the Familial Adenomatous Polyposis</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">minbaev@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богормистров</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogormistrov</surname><given-names>Ilya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат  медицинских наук, врач научно-консультативной поликлиники</p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Doctor, Scientific-consulting clinic</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">dr.bogormistrov@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ким</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kim</surname><given-names>Evgeny V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический аспирант кафедры колопроктологии</p><p>123423, г. Москва, ул. Саляма Адиля, 2</p></bio><bio xml:lang="en"><p>Clinical Post-graduate Student, Department of Coloproctology</p><p>123423, Moscow, Salyama Adilya str., 2.</p></bio><email xlink:type="simple">eugenegost@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Государственный научный центр колопроктологии им. А. Н. Рыжих» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Scientific Center of Coloproctology named after A.N. Ryzhykh</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>29</day><month>03</month><year>2019</year></pub-date><volume>29</volume><issue>1</issue><fpage>31</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фролов С.А., Кузьминов А.М., Вышегородцев Д.В., Королик В.Ю., Минбаев Ш.Т., Богормистров И.С., Ким Е.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Фролов С.А., Кузьминов А.М., Вышегородцев Д.В., Королик В.Ю., Минбаев Ш.Т., Богормистров И.С., Ким Е.В.</copyright-holder><copyright-holder xml:lang="en">Frolov S.A., Kuzminov A.M., Vyshegorodtsev D.V., Korolik V.Y., Minbaev S.T., Bogormistrov I.S., Kim E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/324">https://www.gastro-j.ru/jour/article/view/324</self-uri><abstract><sec><title>Цель обзора</title><p>Цель обзора. Представить данные литературы по лечению свищей прямой кишки с применением фибринового клея.</p></sec><sec><title>Основные положения</title><p>Основные положения. Распространенность свищей прямой кишки составляет от 9 случаев на 100 000 населения. Зачастую пациенты со свищами прямой кишки представлены работоспособной категорией граждан среднего возраста, и крайне редко заболевание наблюдаются у детей и лиц пожилого возраста. Таким образом, эта проблема является социально-трудовой. Ликвидация свища возможна только хирургическим методом и сопровождается риском развития рецидива свища и развитием послеоперационной инконтиненции. В связи с этим активно исследуются малоинвазивные методики лечения свищей прямой кишки, такие как использование фибринового клея.</p></sec><sec><title>Заключение</title><p>Заключение. Применение фибринового клея в качестве сфинктеросохраняющей методики позволяет исключить развитие послеоперационной анальной недостаточности, а новые технологии и материалы снижают риск рецидива.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: to summarize the literature data on the treatment of rectal fistula using fibrin glue.</p></sec><sec><title>Key findings</title><p>Key findings: The prevalence of rectal fistula is about 9 cases per 100,000 population. Patients with rectal fistulas are frequently represented by the able-bodied middle-aged population group. The disease is extremely rarely observed in children and elderly people. Thus, this problem has a socially significant character. Fistula elimination is possible only by surgery, which is accompanied by the risk of fistula recurrence and the development of postoperative incontinence. In this regard, low-invasive techniques for the treatment of rectal fistulas, such as the use of fibrin glue, are being actively investigated.</p></sec><sec><title>Conclusion</title><p>Conclusion: The use of fibrin glue as a sphincter-preserving technique eliminates the development of postoperative anal failure, while new technologies and materials aim to reduce the risk of the disease recurrence.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический парапроктит</kwd><kwd>свищ</kwd><kwd>недостаточность анального сфинктера</kwd><kwd>рецидив заболевания</kwd><kwd>хирургическое лечение</kwd><kwd>фибриновый клей</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic paraproctitis</kwd><kwd>fistula</kwd><kwd>anal sphincter insufficiency</kwd><kwd>disease recurrence</kwd><kwd>surgical treatment</kwd><kwd>fibrin glue</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Abcarian H. 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