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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2019-29-2-76-80</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-357</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАЦИОНАЛЬНАЯ ШКОЛА ГАСТРОЭНТЕРОЛОГОВ, ГЕПАТОЛОГОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NATIONAL COLLEGE OF GASTROENTEROLOGISTS, HEPATOLOGISTS</subject></subj-group></article-categories><title-group><article-title>Диагноз синдрома раздраженного кишечника: должна ли быть онконастороженность?</article-title><trans-title-group xml:lang="en"><trans-title>Irritable Bowel Syndrome Diagnosis: Should There Be Alertness to Cancer?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Prof., Department of Internal Diseases Propedeutics, Medical faculty</p></bio><email xlink:type="simple">arkalshep@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джахая</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Jahaya</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры пропедевтики внутренних болезней</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Research Assistant, Department of Internal Diseases Propedeutics, Medical Faculty</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Седова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sedova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры пропедевтики внутренних болезней</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Research Assistant, Department of Internal Diseases Propedeutics, Medical Faculty</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный университет им. И.М. Сеченова» (Сеченовский университет) Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>05</month><year>2019</year></pub-date><volume>29</volume><issue>2</issue><fpage>76</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шептулин А.А., Джахая Н.Л., Седова А.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шептулин А.А., Джахая Н.Л., Седова А.В.</copyright-holder><copyright-holder xml:lang="en">Sheptulin A.A., Jahaya N.L., Sedova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/357">https://www.gastro-j.ru/jour/article/view/357</self-uri><abstract><sec><title>Цель обзора</title><p>Цель обзора. Обосновать необходимость включения колоректального рака (КРР) в круг дифференциально-диагностического поиска при подозрении на синдром раздраженного кишечника (СРК).</p></sec><sec><title>Основные положения</title><p>Основные положения. В соответствии с последними Римскими критериями СРК IV пересмотра диагноз данного заболевания ставится главным образом на оценке клинических симптомов и данных объективного обследования при очень ограниченном перечне дополнительных исследований. При этом колоноскопия при подозрении на СРК проводится лишь больным старше 50 лет при наличии наследственной предрасположенности к КРР и обнаружении «симптомов тревоги». В настоящее время показано, что КРР может протекать под «маской» СРК. При этом нередко опухоли толстой и прямой кишки могут встречаться у пациентов моложе </p><p>50 лет при отсутствии наследственной предрасположенности к КРР и «симптомов тревоги». Это делает необходимым проведение колоноскопии всем больным с подозрением на СРК.</p></sec><sec><title>Заключение</title><p>Заключение. В перечень заболеваний, требующих проведения дифференциального диагноза у больных с подозрением на СРК, следует обязательно включать КРР.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To justify the need to include colorectal cancer (CRC) in the circle of differential diagnostic search for suspected irritable bowel syndrome (IBS).</p></sec><sec><title>Background</title><p>Background. In accordance with the latest Rome IV criteria for IBS, its diagnosis is mainly based on the assessment of clinical symptoms and objective examination data with a very limited list of additional studies. In this case, colonoscopy for suspected IBS is performed only in patients aged over 50 years old, provided a hereditary predisposition to CRC and the “alarm symptoms” are detected. It has been recently shown that CRC can proceed under the “mask” of IBS. However, colorectal and rectal tumours are often found in patients younger than 50 years old in the absence of hereditary predisposition to CRC and “anxiety symptoms”. This makes it necessary to conduct colonoscopy for all patients with suspected IBS.</p></sec><sec><title>Conclusion</title><p>Conclusion. The list of diseases requiring differential diagnostics in patients with suspected IBS should always include CRC.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром раздраженного кишечника</kwd><kwd>колоректальный рак</kwd><kwd>дифференциальный диагноз</kwd><kwd>колоноскопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>irritable bowel syndrome</kwd><kwd>colorectal cancer</kwd><kwd>differential diagnosis</kwd><kwd>colonoscopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lacy B.E., Mearin F., Chang L. et al. Bowel disorders. Gastroenterology. 2016;150:1393–407.</mixed-citation><mixed-citation xml:lang="en">Lacy B.E., Mearin F., Chang L. et al. Bowel disorders. 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