<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2021-31-3-26-35</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-553</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Абдоминальная боль у лиц молодого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Abdominal Pain in Young Adults</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9370-4768</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаус</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaus</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаус Ольга Владимировна — кандидат медицинских наук, доцент кафедры факультетской терапии, профессиональных болезней, Scopus Author ID: 56598554900</p></bio><bio xml:lang="en"><p>Olga V. Gaus — Cand. Sci. (Med.), Assoc. Prof., Chair of Faculty Therapy and Professional Diseases</p></bio><email xlink:type="simple">gaus_olga@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6581-7017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ливзан</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Livzan</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ливзан Мария Анатольевна — доктор медицинских наук, профессор, ректор, заведующий кафедрой факультетской терапии, профессиональных болезней</p></bio><bio xml:lang="en"><p>Maria A. Livzan — Dr. Sci. (Med.), Prof., Rector, Head of the Chair of Faculty Therapy and Professional Diseases</p></bio><email xlink:type="simple">mlivzan@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6298-4872</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турчанинов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Turchaninov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Турчанинов Денис Владимирович — доктор медицинских наук, профессор, заведующий кафедрой гигиены, питания человека</p></bio><bio xml:lang="en"><p>Denis V. Turchaninov — Dr. Sci. (Med.), Prof., Head of the Chair of Hygiene and Human Nutrition</p></bio><email xlink:type="simple">omskgsen@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Татьяна Ильинична — доктор медицинских наук, доцент, профессор кафедрой психиатрии, клинической психологии</p></bio><bio xml:lang="en"><p>Tatyana I. Ivanova — Dr. Sci. (Med.), Assoc. Prof., Prof., Chair of Psychiatry and Clinical Psychology</p></bio><email xlink:type="simple">tanysikiva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2202-8146</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попелло</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popello</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попелло Дарья Владимировна — студентка 4-го курса лечебного факультета</p></bio><bio xml:lang="en"><p>Daria V. Popello — Graduate Student (4th year), Faculty of Medicine</p></bio><email xlink:type="simple">dvpopello@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Омский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>08</day><month>10</month><year>2021</year></pub-date><volume>31</volume><issue>3</issue><fpage>26</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гаус О.В., Ливзан М.А., Турчанинов Д.В., Иванова Т.И., Попелло Д.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Гаус О.В., Ливзан М.А., Турчанинов Д.В., Иванова Т.И., Попелло Д.В.</copyright-holder><copyright-holder xml:lang="en">Gaus O.V., Livzan M.A., Turchaninov D.V., Ivanova T.I., Popello D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/553">https://www.gastro-j.ru/jour/article/view/553</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить частоту абдоминальной боли у лиц молодого возраста и ассоциацию с характером питания и психологическим профилем личности для оптимизации здоровьесберегающих технологий.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено анонимное анкетирование 3634 студентов, обучающихся в Омском государственном медицинском университете по программам высшего и среднего профессионального образования, с использованием опросника GSRS, опросника программы CINDI ВОЗ для оценки характера питания и пищевых предпочтений, Сокращенного многофакторного опросника для исследования личности посредством онлайн-форм. Респонденты, имеющие абдоминальную боль, были разделены на подгруппы в зависимости от выраженности боли в соответствии с баллами по шкале GSRS (слабая, умеренная и выраженная боль).</p></sec><sec><title>Результаты</title><p>Результаты. Об абдоминальной боли сообщили 2300 (63,29 %) респондентов, из них 1243 (54,0 %) оценили свои симптомы как слабовыраженные, а 996 (43,3 %) и 61 (2,7 %) — как умеренно выраженные и выраженные. Жалобы на наличие абдоминальной боли чаще предъявляли женщины (2I = 33,96, p &lt; 0,001), однако гендерная принадлежность не влияла на интенсивность боли. Абдоминальная боль сочеталась со вздутием и распиранием живота (у 57,65 %), с симптомами гастроэзофагеального рефлюкса (38,75 %), запором (30,54 %), диареей (28,40 %). Наличие и выраженность абдоминальной боли были характерны для лиц, которые большую часть среднего ежемесячного дохода тратят на покупку продуктов питания, а также связаны с повышенным употреблением чая и кофе, добавленного сахара, досаливанием приготовленной пищи, низким употреблением овощей и фруктов. Характерный тип личности при выраженной абдоминальной боли — гипотимный с проявлением депрессии, при умеренно выраженной — ипохондрический, при слабовыраженной — психастенический.</p></sec><sec><title>Выводы</title><p>Выводы. Абдоминальная боль широко распространена у студентов медицинского вуза, преобладает среди лиц женского пола. взаимосвязана с характером питания, пищевыми привычками и психологическим профилем личности.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. A study of abdominal pain incidence in young adults in relation to dietary habits and psychological profile for advancement of health-promoting technologies.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. An anonymous quiz survey covered 3,634 students enrolled at Omsk State Medical University in higher and secondary vocational education programmes via online use of the GSRS and WHO CINDI programme questionnaires to assess eating patterns and dietary preferences, as well as a brief multifactor personality inventory scale. Respondents with abdominal pain were divided into subcohorts by pain severity according to GSRS scores (mild, moderate or severe pain).</p></sec><sec><title>Results</title><p>Results. Abdominal pain was reported by 2,300 (63.29%) respondents, of whom 1,243 (54.0%) rated symptoms as mild, 996 (43.3%) and 61 (2.7%) — as moderate to severe. Abdominal pain complaints were more frequent in women (2I = 33.96, p &lt;0.001), but gender had no effect on pain intensity. Pain associated with abdominal bloating and distention (57.65%), gastroesophageal reflux symptoms (38.75%), constipation (30.54%) or diarrhoea (28.4%). The presence and severity of abdominal pain was distinctive of individuals spending the most of average monthly income on food purchase and those actively consuming tea, coffee, added sugar, extra salt in cooked food, while having low intake of fruit and vegetables. A typical personality in severe abdominal pain is hypothymic depressive, hypochondriac in moderate and psychasthenic in mild pain.</p></sec><sec><title>Conclusion</title><p>Conclusion. Abdominal pain is common among medical students predominating in females, associates with the eating pattern, dietary habits and psychological profile.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>абдоминальная боль</kwd><kwd>факторы риска</kwd><kwd>молодежная среда</kwd><kwd>функциональные гастроинтестинальные расстройства</kwd><kwd>пищевые привычки</kwd><kwd>психологический профиль личности</kwd><kwd>фенотип</kwd><kwd>депрессия</kwd><kwd>ипохондрия</kwd><kwd>психастения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>abdominal pain</kwd><kwd>risk factor</kwd><kwd>youth environment</kwd><kwd>functional gastrointestinal disorder</kwd><kwd>dietary habit</kwd><kwd>psychological profile</kwd><kwd>phenotype</kwd><kwd>depression</kwd><kwd>hypochondriasis</kwd><kwd>psychasthenia</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Грант Президента РФ для государственной поддержки молодых российских ученых – кандидатов наук МК-1679.2020.7 (соглашение № 075-15-2020-138 от 17 марта 2020 года) «Разработка превентивной индивидуализированной стратегии ведения больных с синдромом раздраженного кишечника».</funding-statement><funding-statement xml:lang="en">Grant MK-1679.2020.7 by the President of Russian Federation for state support of young Russian candidates of science, project “Development of preventive personalised management strategy in patients with irritable bowel syndrome” (Agreement 075-15-2020-138 of March 17, 2020)</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Stachowska E., Maciejewska D., Ryterska K., Baszuk P., Skonieczna-Zydecka K., Czerwinska-Rogowska M., et al. Abdominal Pain and Disturbed Bowel Movements are Frequent among Young People. A Population Based Study in Young Participants of the Woodstock Rock Festival in Poland. J Gastrointestin Liver Dis. 2018;27(4):379—83. DOI: 10.15403/jgld.2014.1121.274.pol</mixed-citation><mixed-citation xml:lang="en">Stachowska E., Maciejewska D., Ryterska K., Baszuk P., Skonieczna-Zydecka K., Czerwinska-Rogowska M., et al. Abdominal Pain and Disturbed Bowel Movements are Frequent among Young People. A Population Based Study in Young Participants of the Woodstock Rock Festival in Poland. J Gastrointestin Liver Dis. 2018;27(4):379—83. DOI: 10.15403/jgld.2014.1121.274.pol</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Lakhoo K., Almario C.V., Khalil C., Spiegel B.M.R. Prevalence and Characteristics of Abdominal Pain in the United States. Clin Gastroenterol Hepatol. 2021;19(9):1864—72.e5. DOI: 10.1016/j.cgh.2020.06.065</mixed-citation><mixed-citation xml:lang="en">Lakhoo K., Almario C.V., Khalil C., Spiegel B.M.R. Prevalence and Characteristics of Abdominal Pain in the United States. Clin Gastroenterol Hepatol. 2021;19(9):1864—72.e5. DOI: 10.1016/j.cgh.2020.06.065</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т., Маев И.В., Кучерявый Ю.А., Лапина Т.Л., Баранская Е.К., Осипенко М.Ф. и др. Клинические рекомендации Российской гастроэнтерологической ассоциации по ведению пациентов с абдоминальной болью. Рос журн гастроэнтерол гепатол колопроктол. 2015;25(4):71—80.</mixed-citation><mixed-citation xml:lang="en">Ivashkin V.T., Mayev I..V., Kuch-eryavii Yu.A., Lapina T.L., Baranskaya Ye.K., Osipenko M.F., et al. Management of abdominal pain: clinical guidelines of the Russian gastroenterological association. Rus J Gastroenterol Hepatol Coloproctol. 2015;25(4):71 — 80 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Australian Institute of Health and Welfare. Emergency department care 2016—17: Australian hospital statistics. Health services series no. 80. Cat. no. HSE 194. Canberra: AIHW (2017). https://www.aihw.gov.au/getmedia/981140ee-3957-4d47-9032-18ca89b519b0/aihw-hse-194.pdf.aspx?inline=true (accessed January 2021).</mixed-citation><mixed-citation xml:lang="en">Australian Institute of Health and Welfare. Emergency department care 2016—17: Australian hospital statistics. Health services series no. 80. Cat. no. HSE 194. Canberra: AIHW (2017). https://www.aihw.gov.au/getmedia/981140ee-3957-4d47-9032-18ca89b519b0/aihw-hse-194.pdf.aspx?inline=true (accessed January 2021).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Drossman D.A. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016;150:1262-79. DOI: 10.1053/j.gastro.2016.02.032</mixed-citation><mixed-citation xml:lang="en">Drossman D.A. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016;150:1262-79. DOI: 10.1053/j.gastro.2016.02.032</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Андреев Д.Н., Заборовский А.В., Трухманов А.С., Маев И.В., Ивашкин В.Т. Эволюция представлений о функциональных заболеваниях желудочно-кишечного тракта в свете Римских критериев IV пересмотра (2016 г.). Рос журн гастроэнтерол гепатол колопроктол. 2017;27(1):4—11. DOI: 10.22416/1382-4376-2017-27-1-4-11</mixed-citation><mixed-citation xml:lang="en">Andreyev D.N., Zaborovsky A.V., Trukhmanov A.S., Mayev I.V., Ivashkin V.T. Evaluation of the functional gastrointestinal diseases concept from standpoints of Rome IV (2016) diagnostic criteria (review). Rus J Gastroenterol Hepatol Coloproctol. 2017;27(1):4—11 (In Russ.). DOI: 10.22416/1382-4376-2017-27-1-4-11</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ливзан М.А., Гаус О.В., Турчанинов Д.В., Попелло Д.В. Синдром абдоминальной боли в молодежной среде: распространенность и факторы риска. Экспериментальная и клиническая гастроэнтерология. 2019;170(10):12—7. DOI: 10.31146/1682-8658-ecg-170-10-12-17</mixed-citation><mixed-citation xml:lang="en">Livzan M.A., Gaus O.V., Turchani-nov D.V., Popello D.V. Abdominal Pain Syndrome in Youth: Prevalence and Risk Factors. Experimental and Clinical Gastroenterology. 2019;1(10):12—7 (In Russ.). DOI: 10.31146/1682-8658-ecg-170-10-12-17</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">WHO Europe. CINDI Health Monitor: A Study of feasibility of a health behaviour monitoring survey across CINDI countries. Data book [Internet]. 2000. Accessed: http://www.euro.who.int/data/assets/pdf_file/0017/240236/e79396.pdf</mixed-citation><mixed-citation xml:lang="en">WHO Europe. CINDI Health Monitor: A Study of feasibility of a health behaviour monitoring survey across CINDI countries. Data book [Internet]. 2000. Accessed: http://www.euro.who.int/data/assets/pdf_file/0017/240236/e79396.pdf</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Rauf Q.S., Abdelaal A.M., Janjua Z.A., Alasmari H.A., Obad A.S., Alamodi A., Shareef M.A. Irritable Bowel Syndrome: A Global Challenge Among Medical Students. Cureus. 2016;8(8):e721. DOI: 10.7759/cureus.721</mixed-citation><mixed-citation xml:lang="en">Rauf Q.S., Abdelaal A.M., Janjua Z.A., Alasmari H.A., Obad A.S., Alamodi A., Shareef M.A. Irritable Bowel Syndrome: A Global Challenge Among Medical Students. Cureus. 2016;8(8):e721. DOI: 10.7759/cureus.721</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Choi Y.J., Kim N., Yoon H., Shin C.M., Park Y.S., Kim J.W., et al. Overlap between irritable bowel syndrome and functional dyspepsia including subtype analyses. J. Gastroenterol Hepatol. 2017;32:1553-61. DOI: 10.1111/jgh.13756</mixed-citation><mixed-citation xml:lang="en">Choi Y.J., Kim N., Yoon H., Shin C.M., Park Y.S., Kim J.W., et al. Overlap between irritable bowel syndrome and functional dyspepsia including subtype analyses. J. Gastroenterol Hepatol. 2017;32:1553-61. DOI: 10.1111/jgh.13756</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Meleine M., Matricon J. Gender-related differences in irritable bowel syndrome: potential mechanisms of sex hormones. World J. Gastroenterol. 2014;20:6725-43. DOI: 10.3748/wjg.v20.i22.6725</mixed-citation><mixed-citation xml:lang="en">Meleine M., Matricon J. Gender-related differences in irritable bowel syndrome: potential mechanisms of sex hormones. World J. Gastroenterol. 2014;20:6725-43. DOI: 10.3748/wjg.v20.i22.6725</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kim Y.S., Kim N. Sex-Gender Differences in Irritable Bowel Syndrome. J. Neurogastroenterol. Motil. 2018;24(4):544—58. DOI: 10.5056/jnm18082</mixed-citation><mixed-citation xml:lang="en">Kim Y.S., Kim N. Sex-Gender Differences in Irritable Bowel Syndrome. J. Neurogastroenterol. Motil. 2018;24(4):544—58. DOI: 10.5056/jnm18082</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Meerveld B.G., Johnson A.C. Mechanisms of stress-induced visceral pain. J Neurogastroenterol Motil. 2018;24:7—18. DOI: 10.5056/jnm171</mixed-citation><mixed-citation xml:lang="en">Meerveld B.G., Johnson A.C. Mechanisms of stress-induced visceral pain. J Neurogastroenterol Motil. 2018;24:7—18. DOI: 10.5056/jnm171</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Tavakoly R., Motlagh A.D., Eshraghian M., Tavakoly R., Mirabdolhagh M. Association Between Food Insecurity And Some Socio-Economic Factors And Functional Dyspepsia In Adult Women. International Research Journal of Applied and Basic Sciences. 2014;8(2):219—23.</mixed-citation><mixed-citation xml:lang="en">Tavakoly R., Motlagh A.D., Eshraghian M., Tavakoly R., Mirabdolhagh M. Association Between Food Insecurity And Some Socio-Economic Factors And Functional Dyspepsia In Adult Women. International Research Journal of Applied and Basic Sciences. 2014;8(2):219—23.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Clark R.L., Famodu O.A., Barr M., Hagedorn R.L., Ruseski J., White J.A., Warner C.M., et al. Monetary Cost of the MyPlate Diet in Young Adults: Higher Expenses Associated with Increased Fruit and Vegetable Consumption. J Nutr Metab. 2019;2019:2790963. DOI: 10.1155/2019/2790963</mixed-citation><mixed-citation xml:lang="en">Clark R.L., Famodu O.A., Barr M., Hagedorn R.L., Ruseski J., White J.A., Warner C.M., et al. Monetary Cost of the MyPlate Diet in Young Adults: Higher Expenses Associated with Increased Fruit and Vegetable Consumption. J Nutr Metab. 2019;2019:2790963. DOI: 10.1155/2019/2790963</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Sethi S., Richter J.E. Diet and gastroesophageal reflux disease: role in pathogenesis and management. Curr Opin Gastroenterol. 2017;33(2):107—11. DOI: 10.1097/MOG.0000000000000337</mixed-citation><mixed-citation xml:lang="en">Sethi S., Richter J.E. Diet and gastroesophageal reflux disease: role in pathogenesis and management. Curr Opin Gastroenterol. 2017;33(2):107—11. DOI: 10.1097/MOG.0000000000000337</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ахмедов В.А., Орлов И.Н., Гаус О.В. Современные методы реабилитации пациентов с синдромом раздраженного кишечника. Терапия. 2017;3(13):49—55.</mixed-citation><mixed-citation xml:lang="en">Akhm-edov V.A., Orlov I.N., Gaus O.V. Modern methods of rehabilitation of patients with irritable bowel syndrome. Therapy. 2017;3(13):49—55 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Глобальные практические рекомендации Всемирной Гастроэнтерологической Организации. Диета и кишечник. 2018. https://www.worldgastroenterology.org/User-Files/file/guidelines/diet-and-the-gut-russian.pdf</mixed-citation><mixed-citation xml:lang="en">Глобальные практические рекомендации Всемирной Гастроэнтерологической Организации. Диета и кишечник. 2018. https://www.worldgastroenterology.org/User-Files/file/guidelines/diet-and-the-gut-russian.pdf</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Patcharatrakul T., Gonlachanvit S. Chili Peppers, Cur-cumins, and Prebiotics in Gastrointestinal Health and Disease. Curr. Gastroenterol. Rep. 2016;18:19. DOI: 10.1007/s11894-016-0494-02</mixed-citation><mixed-citation xml:lang="en">Patcharatrakul T., Gonlachanvit S. Chili Peppers, Curcumins, and Prebiotics in Gastrointestinal Health and Disease. Curr. Gastroenterol. Rep. 2016;18:19. DOI: 10.1007/s11894-016-0494-02</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">El-Salhy M., Hatlebakk G., Hausken T. Diet in irritable bowel syndrome (IBS): interaction with gut microbiota and gut hormones. Nutrients. 2019;11:1824. DOI: 10.3390/nu11081824</mixed-citation><mixed-citation xml:lang="en">El-Salhy M., Hatlebakk G., Hausken T. Diet in irritable bowel syndrome (IBS): interaction with gut microbiota and gut hormones. Nutrients. 2019;11:1824. DOI: 10.3390/nu11081824</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Engel G. The need for a new medical model: a challenge for biomedicine. Science. 1977;196:129—36.</mixed-citation><mixed-citation xml:lang="en">Engel G. The need for a new medical model: a challenge for biomedicine. Science. 1977;196:129—36.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
