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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2016-26-3-81-86</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-62</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВОСТИ КОЛОПРОКТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEWS OF COLOPROCTOLOGY</subject></subj-group></article-categories><title-group><article-title>Возможности применения биоматериалов в лечении свищей прямой кишки (Обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Options of biological substances application in rectal fistulas treatment (Review of the literature)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьминов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzminov</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Frolov</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вышегородцев</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyshegorodtsev</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королик</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolik</surname><given-names>V. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минбаев</surname><given-names>Ш. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Minbayev</surname><given-names>Sh. T.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богормистров</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogormistrov</surname><given-names>I. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черножукова</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernozhukova</surname><given-names>M. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Государственный научный центр колопроктологии им. А.Н. Рыжих»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal government-financed institution «Ryzhikh state scientific center of coloproctology»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>12</day><month>08</month><year>2016</year></pub-date><volume>26</volume><issue>3</issue><fpage>81</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузьминов А.М., Фролов С.А., Вышегородцев Д.В., Королик В.Ю., Минбаев Ш.Т., Богормистров И.С., Черножукова М.О., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Кузьминов А.М., Фролов С.А., Вышегородцев Д.В., Королик В.Ю., Минбаев Ш.Т., Богормистров И.С., Черножукова М.О.</copyright-holder><copyright-holder xml:lang="en">Kuzminov A.M., Frolov S.A., Vyshegorodtsev D.V., Korolik V.Y., Minbayev S.T., Bogormistrov I.S., Chernozhukova M.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/62">https://www.gastro-j.ru/jour/article/view/62</self-uri><abstract><p>Цель обзора. Ознакомить с данными литературы по лечению неполных свищей прямой кишки с применением биоматериалов. Основные положения. Лечение свищей прямой кишки остается актуальным вопросом колопроктологии. Это связано с неудовлетворительными результатами выполняемых операций, сопровождающихся высокой частотой рецидива заболевания, как правило, вне зависимости от примененного метода хирургического вмешательства, а также с вероятностью возникновения такого серьезного осложнения, как недостаточность анального сфинктера. Именно по данной причине важна разработка щадящих методов лечения свищей прямой кишки, позволяющих при минимизированном риске возврата заболевания снизить интраоперационную травматизацию анального сфинктера и тем самым избежать развития недостаточности последнего. Применение биоматериалов в лечении свищей прямой кишки дает возможность сократить размеры раны, ускоряет процессы регенерации и уменьшает степень травматизации. Минимизация объема оперативного воздействия на анальный сфинктер создает предпосылки для повторного использования биоматериалов, вплоть до достижения положительного результата. Заключение. С применением биоматериалов как сфинктерощадящей методики расширились возможности для исключения развития послеоперационной анальной недостаточности.</p></abstract><trans-abstract xml:lang="en"><p>Aim of review. To present literature data of the treatment of incomplete rectal fistulas with application of biological substances. Summary. Treatment of rectal fistulas remains burning issue in coloproctology due to unsatisfactory results of surgery resulting in high relapse rate, usually regardless of applied surgical method and high risk of severe complications as anal sphincter incompetence. This is why development of sparing methods of rectal fistula treatment that will allow to decrease intraoperative trauma of the anal sphincter at minimal risk of disease recurrence and, therefore, to prevent development of sphincter incompetence is important. Application of biological materials in rectal fistulas treatment result in reduction of the wound size, accelerates reparative processes and decreases degree of traumatization. Minimization of surgical impact on the anal sphincter allows repetitive application of biological materials up to the achievement of positive effect. Conclusion. Application of biological materials at sphincter-preserving technique provides decreased risk of development of postoperative anal sphincter incompetence.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>свищ прямой кишки</kwd><kwd>фибриновый клей</kwd><kwd>коллагеновые импланты</kwd><kwd>плазма</kwd><kwd>обогащенная тромбоцитарными факторами роста</kwd><kwd>аутологические стволовые клетки</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аминев А.М. Руководство по проктологии. Куйбышев, 1971.</mixed-citation><mixed-citation xml:lang="en">Аминев А.М. Руководство по проктологии. Куйбышев, 1971.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Севастьянов В.И., Кирпичнников М.П. Биологические материалы: Учебное пособие. 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