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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2022-32-3-52-56</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-671</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАЦИОНАЛЬНАЯ ШКОЛА ГАСТРОЭНТЕРОЛОГИИ, ГЕПАТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NATIONAL COLLEGE OF GASTROENTEROLOGY, HEPATOLOGY</subject></subj-group></article-categories><title-group><article-title>Функциональные заболевания желудочно-кишечного тракта в период пандемии новой коронавирусной инфекции COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Functional Disorders of the Gastrointestinal Tract During the Pandemic of a New Coronavirus Infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1395-9566</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шептулин Аркадий Александрович — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии</p><p>119435, г. Москва, ул. Погодинская, д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Arkadiy A. Sheptulin — Dr. Sci. (Med.), Prof., Chair of Internal Diseases Propedeutics, Gastroenterology and Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, bld. 1</p><p> </p></bio><email xlink:type="simple">arkalshep@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5037-7955</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пятенко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Piatenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пятенко Елена Александровна — аспирант кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии</p><p>119435, г. Москва, ул. Погодинская, д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Elena A. Piatenko — postgraduate student, Chair of Internal Diseases Propedeutics, Gastroenterology and Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, bld. 1</p></bio><email xlink:type="simple">piatenkoe@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» (Сеченовский Университет) Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>10</day><month>09</month><year>2022</year></pub-date><volume>32</volume><issue>3</issue><fpage>52</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шептулин А.А., Пятенко Е.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Шептулин А.А., Пятенко Е.А.</copyright-holder><copyright-holder xml:lang="en">Sheptulin A.A., Piatenko E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/671">https://www.gastro-j.ru/jour/article/view/671</self-uri><abstract><sec><title>Цель обзора</title><p>Цель обзора. Провести анализ данных литературы, посвященных изучению особенностей функциональных заболеваний желудочно-кишечного тракта (ЖКТ) в период пандемии новой коронавирусной инфекции.</p></sec><sec><title>Основные положения</title><p>Основные положения. Меры, принимаемые в связи с пандемией инфекции COVID-19 (введение локдауна, социальная изоляция), ведут к повышению уровня депрессии и тревоги и, как следствие, к увеличению частоты и распространенности функциональной диспепсии (ФД) и синдрома раздраженного кишечника (СРК), а также усилению выраженности клинических симптомов этих заболеваний. В свою очередь, перенесенная инфекция COVID-19 способствует повышению проницаемости слизистой оболочки желудочно-кишечного тракта и возникновению ее воспалительных изменений, что в дальнейшем может приводить к развитию постинфекционной (постковидной) ФД и постинфекционного (постковидного) СРК.</p></sec><sec><title>Заключение</title><p>Заключение. Новая коронавирусная инфекция оказывает негативное влияние на течение ФД и СРК, что выражается в нарастании выраженности их клинических симптомов. Перенесенный COVID-19, особенно протекавший с гастроинтестинальными симптомами, может способствовать развитию функциональных расстройств. Особенности возникновения функциональных расстройств ЖКТ, их течения и лечения в условиях пандемии изучены недостаточно и требуют дальнейших исследований.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To analyze the literature data devoted to the study of the features of functional gastrointestinal diseases (FGID) during the pandemic of a new coronavirus infection.</p></sec><sec><title>Key findings</title><p>Key findings. Measures taken in connection with the pandemic of COVID-19 infection (introduction of lockdown, social isolation) leads to an increase in the level of depression and anxiety and, as a consequence, to an increase in the frequency and prevalence of functional dyspepsia (FD) and irritable bowel syndrome (IBS), as well as an increase in the severity of clinical symptoms of these diseases. In turn, the overcoming of COVID-19 infection contributes to an increase in the permeability of the mucous membrane of the gastrointestinal tract and the occurrence of its inflammatory changes, which lead to the development of postinfectious (postcovid) FD and postinfectious (postcovid) IBS.</p></sec><sec><title>Conclusion</title><p>Conclusion. The problem of functional gastrointestinal diseases during the pandemic of a new coronavirus infection is very important and requires further research.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекция COVID-19</kwd><kwd>функциональная диспепсия</kwd><kwd>синдром раздраженного кишечника</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19 infection</kwd><kwd>functional dyspepsia</kwd><kwd>irritable bowel syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Salari N., Hosseinian-Far A., Jalali R., Vaisi-Raygani A., Rasoulpoor S., Mohammadi M., et al. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis. Global Health. 2020;16(1):57. DOI: 10.1186/s12992-020-00589-w</mixed-citation><mixed-citation xml:lang="en">Salari N., Hosseinian-Far A., Jalali R., Vaisi-Raygani A., Rasoulpoor S., Mohammadi M., et al. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis. Global Health. 2020;16(1):57. DOI: 10.1186/s12992-020-00589-w</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Nakov R., Dimitrova-Yurukova D., Snegarova V., Nakov V., Fox M., Heinrich H. Increased prevalence of gastrointestinal symptoms and disorders of gut-brain interaction during the COVID-19 pandemic: An internet-based survey. Neurogastroenterol Motil. 2022;34(2):e14197. DOI: 10.1111/nmo.14197</mixed-citation><mixed-citation xml:lang="en">Nakov R., Dimitrova-Yurukova D., Snegarova V., Nakov V., Fox M., Heinrich H. Increased prevalence of gastrointestinal symptoms and disorders of gut-brain interaction during the COVID-19 pandemic: An internet-based survey. Neurogastroenterol Motil. 2022;34(2):e14197. DOI: 10.1111/nmo.14197</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Otani K., Watanabe T., Higashimori A., Suzuki H., Kamiya T., Shiotani A., et al. A questionnaire-based survey on the impact of the COVID-19 pandemic on gastrointestinal endoscopy in Asia. Digestion. 2022;103(1):7–21. DOI: 10.1159/000520287</mixed-citation><mixed-citation xml:lang="en">Otani K., Watanabe T., Higashimori A., Suzuki H., Kamiya T., Shiotani A., et al. A questionnaire-based survey on the impact of the COVID-19 pandemic on gastrointestinal endoscopy in Asia. Digestion. 2022;103(1):7–21. DOI: 10.1159/000520287</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Oshima T., Siah KT.H.., Yoshimoto T., Miura K., Toshohiko T., Fukui H. et al. Impacts of the COVID-19 pandemic on functional dyspepsia and irritable bowel syndrome: A population-based survey. J Gastroenterol Hepatol. 2021;36(7):1820–7. DOI: 10.1111/jgh.15346</mixed-citation><mixed-citation xml:lang="en">Oshima T., Siah KT.H.., Yoshimoto T., Miura K., Toshohiko T., Fukui H. et al. Impacts of the COVID-19 pandemic on functional dyspepsia and irritable bowel syndrome: A population-based survey. J Gastroenterol Hepatol. 2021;36(7):1820–7. DOI: 10.1111/jgh.15346</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Oliviero G., Ruggiero L., D’Antonio E., Gagliardi M., Nunziata R., Di Sarno A., et al. Impact of COVID-19 lockdown on symptoms in patients with functional gastrointestinal disorders: Relationship with anxiety and perceived stress. Neurogastroenterol Motil. 2021 May;33(5):e14092. DOI: 10.1111/nmo.14092</mixed-citation><mixed-citation xml:lang="en">Oliviero G., Ruggiero L., D’Antonio E., Gagliardi M., Nunziata R., Di Sarno A., et al. Impact of COVID-19 lockdown on symptoms in patients with functional gastrointestinal disorders: Relationship with anxiety and perceived stress. Neurogastroenterol Motil. 2021 May;33(5):e14092. DOI: 10.1111/nmo.14092</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Sabate J.-M., Deutsch D., Melchior C., Entremont A., Mion F., Bouchoucha M., et al. COVID-19 pandemic and lockdown stress consequences in people with and without irritable bowel syndrome. Ethics Med Public Health. 2021;18:100660. DOI: 10.1016/j.jemep.2021.100660</mixed-citation><mixed-citation xml:lang="en">Sabate J.-M., Deutsch D., Melchior C., Entremont A., Mion F., Bouchoucha M., et al. COVID-19 pandemic and lockdown stress consequences in people with and without irritable bowel syndrome. Ethics Med Public Health. 2021;18:100660. DOI: 10.1016/j.jemep.2021.100660</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Xin Zi Quek S., Xiu Ling Loo E., Demutska A., Chun En Chua, Guan Sen Kew , Wong S., et al. Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome. J Gastroenterol Hepatol. 2021;36(8):2187–97. DOI: 10.1111/jgh.15466</mixed-citation><mixed-citation xml:lang="en">Xin Zi Quek S., Xiu Ling Loo E., Demutska A., Chun En Chua, Guan Sen Kew , Wong S., et al. Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome. J Gastroenterol Hepatol. 2021;36(8):2187–97. DOI: 10.1111/jgh.15466</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Alzahrani M.A., Alshamrani A.S., Ahmassani I.M., Alahmari F.S., Asiri A.H., Alshehri A.M., et al. Coronavirus disease 2019 pandemic stress and its effects on irritable bowel syndrome patients in Saudi Arabia. Medicine (Baltimore). 2020;99(51):e23711. DOI: 10.1097/MD.0000000000023711</mixed-citation><mixed-citation xml:lang="en">Alzahrani M.A., Alshamrani A.S., Ahmassani I.M., Alahmari F.S., Asiri A.H., Alshehri A.M., et al. Coronavirus disease 2019 pandemic stress and its effects on irritable bowel syndrome patients in Saudi Arabia. Medicine (Baltimore). 2020;99(51):e23711. DOI: 10.1097/MD.0000000000023711</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Xiao Jing Wang, Murphy B., Breen-Lyles M., Fox J. Response to Oliviero et al.' s publication: “Impact of COVID-19 lockdown on symptoms in patients with functional gastrointestinal disorders: Relationship with anxiety and perceived stress”. Neurogastroenterol Motil. 2021:e14207. DOI: 10.1111/nmo.14207</mixed-citation><mixed-citation xml:lang="en">Xiao Jing Wang, Murphy B., Breen-Lyles M., Fox J. Response to Oliviero et al.' s publication: “Impact of COVID-19 lockdown on symptoms in patients with functional gastrointestinal disorders: Relationship with anxiety and perceived stress”. Neurogastroenterol Motil. 2021:e14207. DOI: 10.1111/nmo.14207</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kamp K.J., Levy R.L., Munson S.A., Heitkemper M.M. Impact of COVID-19 on individuals with irritable bowel syndrome and comorbid anxiety and/or depression. J Clin Gastroenterol. 2021.1097/MCG.0000000000001515. DOI: 10.1097/MCG.0000000000001515</mixed-citation><mixed-citation xml:lang="en">Kamp K.J., Levy R.L., Munson S.A., Heitkemper M.M. Impact of COVID-19 on individuals with irritable bowel syndrome and comorbid anxiety and/or depression. J Clin Gastroenterol. 2021.1097/MCG.0000000000001515. DOI: 10.1097/MCG.0000000000001515</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Schmulson M., Gudino-Zayas M., Hani A., Sociedad Latinoamericana de Neurogastroenterologia. The impact of COVID-19 pandemic on neurogastroenterologists in Latin America: Results of an online survey. J Clin Gastroenterol. 2021;55(8):684–90. DOI: 10.1097/MCG.0000000000001413</mixed-citation><mixed-citation xml:lang="en">Schmulson M., Gudino-Zayas M., Hani A., Sociedad Latinoamericana de Neurogastroenterologia. The impact of COVID-19 pandemic on neurogastroenterologists in Latin America: Results of an online survey. J Clin Gastroenterol. 2021;55(8):684–90. DOI: 10.1097/MCG.0000000000001413</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Gubatan J., Zikos T., Bishop E.S., Wu J., Gottfried A., Becker L., et al. Gastrointestinal symptoms and healthcare utilization have increased among patients with functional gastrointestinal and motility disorders during the COVID-19 pandemic. Neurogastroenterol Motil. 2021;e14243. DOI: 10.1111/nmo.14243</mixed-citation><mixed-citation xml:lang="en">Gubatan J., Zikos T., Bishop E.S., Wu J., Gottfried A., Becker L., et al. Gastrointestinal symptoms and healthcare utilization have increased among patients with functional gastrointestinal and motility disorders during the COVID-19 pandemic. Neurogastroenterol Motil. 2021;e14243. DOI: 10.1111/nmo.14243</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Almario C.A., Chey W.D., Spiegel B.M.R. Increased risk of COVID-19 among users of proton pump inhibitors. Аm J Gastroenterol. 2020;115(10):1707–15. DOI: 10.14309/ajg.0000000000000798</mixed-citation><mixed-citation xml:lang="en">Almario C.A., Chey W.D., Spiegel B.M.R. Increased risk of COVID-19 among users of proton pump inhibitors. Аm J Gastroenterol. 2020;115(10):1707–15. DOI: 10.14309/ajg.0000000000000798</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Farello F., Di Lucia A., Fioravanti B., Tambucci R., Stagi S., Gaudino R. Analysis of the impact of COVID-19 pandemic on functional gastrointestinal disorders among paediatric population. Eur Rev Med Pharmacol Sci. 2021;25(18):5836–42. DOI: 10.26355/eurrev_202109_26802</mixed-citation><mixed-citation xml:lang="en">Farello F., Di Lucia A., Fioravanti B., Tambucci R., Stagi S., Gaudino R. Analysis of the impact of COVID-19 pandemic on functional gastrointestinal disorders among paediatric population. Eur Rev Med Pharmacol Sci. 2021;25(18):5836–42. DOI: 10.26355/eurrev_202109_26802</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ghoshal U.C., Ghoshal U., Rahman M.M., Mathur A., Rai S., Akhter M., et al. Post-infection functional gastrointestinal disorders following coronavirus disease-19: A case-control study. J.Gastroenterol Hepatol. 2021 Published online Oct 20. DOI: 10.1111/jgh.15717</mixed-citation><mixed-citation xml:lang="en">Ghoshal U.C., Ghoshal U., Rahman M.M., Mathur A., Rai S., Akhter M., et al. Post-infection functional gastrointestinal disorders following coronavirus disease-19: A case-control study. J.Gastroenterol Hepatol. 2021 Published online Oct 20. DOI: 10.1111/jgh.15717</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Velez C., Paz M., Silvernale C., Stratton L.W., Kuo B., Staller K., et al. Factors associated with chronic de novo post-coronavirus disease gastrointestinal disorders in a metropolitan US county. Clin Gastroenterol Hepatol. 2021;S1542-3565(21)01133-2. DOI: 10.1016/j.cgh.2021.10.020</mixed-citation><mixed-citation xml:lang="en">Velez C., Paz M., Silvernale C., Stratton L.W., Kuo B., Staller K., et al. Factors associated with chronic de novo post-coronavirus disease gastrointestinal disorders in a metropolitan US county. Clin Gastroenterol Hepatol. 2021;S1542-3565(21)01133-2. DOI: 10.1016/j.cgh.2021.10.020</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Blackett J.W., Li J., Jodorkovsky D., Freedberg D.E. Prevalence and risk factors for gastrointestinal symptoms after recovery from COVID-19 Neurogastroenterol Motil. 2021;e14251. DOI: 10.1111/nmo.14251</mixed-citation><mixed-citation xml:lang="en">Blackett J.W., Li J., Jodorkovsky D., Freedberg D.E. Prevalence and risk factors for gastrointestinal symptoms after recovery from COVID-19 Neurogastroenterol Motil. 2021;e14251. DOI: 10.1111/nmo.14251</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ruotolo M., Gagliardi M., Ciacci C., Zingone F., de Santis Ciacci C., Santanicola A., et al. Increased COVID-19 lockdown burden in Italian adults with gastrointestinal diseases. Nutrients. 2021;13 (6):1820. DOI: 10.3390/nu13061820</mixed-citation><mixed-citation xml:lang="en">Ruotolo M., Gagliardi M., Ciacci C., Zingone F., de Santis Ciacci C., Santanicola A., et al. Increased COVID-19 lockdown burden in Italian adults with gastrointestinal diseases. Nutrients. 2021;13 (6):1820. DOI: 10.3390/nu13061820</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Noviello D., Costantino A., Muscatello A., Bandera A., Consonni D., Vecchi M., et al. Functional gastrointestinal and somatoform symptoms five months after SARS-CoV-2 infection: A controlled cohort study. Neurogastroenterol Motil. 2022;34(2):e14187. DOI: 10.1111/nmo.14187</mixed-citation><mixed-citation xml:lang="en">Noviello D., Costantino A., Muscatello A., Bandera A., Consonni D., Vecchi M., et al. Functional gastrointestinal and somatoform symptoms five months after SARS-CoV-2 infection: A controlled cohort study. Neurogastroenterol Motil. 2022;34(2):e14187. DOI: 10.1111/nmo.14187</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Шептулин А.А. Диарея у пациентов с инфекцией COVID-19. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2020;30(6):51–6. DOI: 10.22416/1382-4376-2020-30-6-51-56</mixed-citation><mixed-citation xml:lang="en">Sheptulin A.A. Diarrhoea in patients with COVID-19. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(6):51–6 (In Russ.). DOI: 10.22416/1382-4376-2020-30-6-51-56</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Ghoshal U.C. Postinfection irritable bowel syndrome. Gut Liver. 2021. Published online November 18. DOI: 10.5009/gnl210208</mixed-citation><mixed-citation xml:lang="en">Ghoshal U.C. Postinfection irritable bowel syndrome. Gut Liver. 2021. Published online November 18. DOI: 10.5009/gnl210208</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Settani C.R., Ianiro G., Ponziani F.R., Bibbo S., Segal J.P., Cammrota G., et al. COVID-19 as a trigger of irritable bowel syndrome: A review of potential mechanisms. World J Gastroenterol. 2021;27(43):7433–45. DOI: 10.3748/wjg.v27.i43.7433</mixed-citation><mixed-citation xml:lang="en">Settani C.R., Ianiro G., Ponziani F.R., Bibbo S., Segal J.P., Cammrota G., et al. COVID-19 as a trigger of irritable bowel syndrome: A review of potential mechanisms. World J Gastroenterol. 2021;27(43):7433–45. DOI: 10.3748/wjg.v27.i43.7433</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Cooney J., Appiahene P., Findlay R., Al-Hillawi L., Rafique K., Laband W., et al. COVID-19 infection causing residual gastrointestinal symptoms — a single UK centre case series. Clin Med (Lond). 2022 Feb 1; clinmed.2021-0522. Published online. DOI: 10.7861/clinmed.2021-0522</mixed-citation><mixed-citation xml:lang="en">Cooney J., Appiahene P., Findlay R., Al-Hillawi L., Rafique K., Laband W., et al. COVID-19 infection causing residual gastrointestinal symptoms — a single UK centre case series. Clin Med (Lond). 2022 Feb 1; clinmed.2021-0522. Published online. DOI: 10.7861/clinmed.2021-0522</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
