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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2022-32-2-99-156</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-703</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GUIDELINES</subject></subj-group></article-categories><title-group><article-title>Клинические рекомендации по диагностике и лечению хронического панкреатита</article-title><trans-title-group xml:lang="en"><trans-title>Clinical Guidelines  of the Russian Society of Surgeons, the Russian Gastroenterological Association, the Association of Surgeons-Hepatologists and the Endoscopic Society “REndO” on Diagnostics and Treatment of Chronic Pancreatitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6815-6015</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивашкин</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivashkin</surname><given-names>V. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивашкин Владимир Трофимович — доктор медицинских наук, академик РАН, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологии и гепатологии; директор клиники пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х. Василенко УКБ № 2 </p><p>119435, Москва, Погодинская ул., д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Vladimir T. Ivashkin — Dr. Sci. (Med.), Full Member of the Russian Academy of Sciences, Head of the Chair of Internal Disease Propaedeutics, Gastroenterology and Hepatology;  Director, Vasilenko Clinic of Internal Disease Propaedeutics, Gastroenterology and Hepatology, University Clinical Hospital No. 2</p><p>19435, Moscow, Pogodinskaya str., 1, bld. 1</p></bio><email xlink:type="simple">ivashkin_v_t@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4539-9943</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кригер</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kriger</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кригер Андрей Германович — доктор медицинских наук, профессор, заведующий отделением абдоминальной хирургии</p><p>117997, Москва, Большая Серпуховская ул., 27</p></bio><bio xml:lang="en"><p>Andrey G. Kriger — Dr. Sci. (Med.), Prof., Head of the Department of Abdominal Surgery</p><p>117997, Moscow, Bolshaya Serpukhovskaya str., 27</p></bio><email xlink:type="simple">kriger@ixv.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4617-2292</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охлобыстин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhlobystin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Охлобыстин Алексей Викторович — кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии</p><p>119435, Москва, Погодинская ул., д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Aleksey V. Okhlobystin — Cand. Sci. (Med.), Assoc. Prof., Chair of Internal Disease Propaedeutics, Gastroenterology and Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, bld. 1</p></bio><email xlink:type="simple">okhlobystin_a_v@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4255-0783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анищенко</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Anischenko</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анищенко Мария Александровна — кандидат медицинских наук, научный сотрудник научно-исследовательской лаборатории хирургической гастроэнтерологии и эндоскопии при кафедре госпитальной хирургии № 2 лечебного факультета; врач-эндоскопист ГБУЗ «Городская клиническая больница № 31» Департамента здравоохранения г. Москвы</p><p> </p></bio><bio xml:lang="en"><p>Mariya A. Anischenko — Cand. Sci. (Med.), Researcher, Research Laboratory of Surgical Gastroenterology and Endoscopy, Chair of Hospital Surgery No. 2, Faculty of General Medicine; Physician (endoscopy), City Clinical Hospital No. 31, Moscow City Department of Health</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кардашева</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kardasheva</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кардашева Светлана Станиславовна — кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии </p><p>119435, Москва, Погодинская ул., д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Svetlana S. Kardasheva — Cand. Sci. (Med.), Assoc. Prof., Chair of Internal Disease Propaedeutics, Gastroenterology and Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, bld. 1</p></bio><email xlink:type="simple">kardasheva_s_s@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1724-9980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseenko</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеенко Сергей Алексеевич — доктор медицинских наук, заведующий кафедрой госпитальной терапии; руководитель Клиники внутренних болезней Дорожной клинической больницы на ст. Хабаровск-1 Дальневосточной железной дороги; главный внештатный гастроэнтеролог Дальневосточного федерального округа</p><p>680000, г. Хабаровск, ул. Запарина, д. 83</p></bio><bio xml:lang="en"><p>Sergey A. Alekseenko — Dr. Sci. (Med.), Head of the Chair of Hospital Therapy; Head of the Clinic of Internal Medicine, Khabarovsk-1 Railway Clinical Hospital, Far-Eastern Railways; Chief External Expert (gastroenterology), Far-Eastern Federal District</p><p>680000, Khabarovsk, Zaparina str., 83</p></bio><email xlink:type="simple">sa.alexeenko@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6380-137X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Багненко</surname><given-names>С. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Bagnenko</surname><given-names>S. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Багненко Сергей Федорович — доктор медицинских наук, профессор, академик РАН, ректор </p><p>119435, Москва, Погодинская ул., д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Sergey F. Bagnenko — Dr. Sci. (Med.), Prof., Full Member of the Russian Academy of Sciences, Rector</p><p>197022, St. Petersburg, Lva Tolstogo str., 6–8</p></bio><email xlink:type="simple">rector@1spbgmu.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6806-1414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быков</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykov</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Быков Михаил Ильич — доктор медицинских наук, профессор кафедры хирургии № 1 ФПК и ППС; заведующий эндоскопическим отделением № 2 НИИ-Краевая клиническая больница №1 им. С. В. Очаповского</p><p>350000, г. Краснодар, ул. им. М. Седина, д. 4</p></bio><bio xml:lang="en"><p>Mikhail I. Bykov — Dr. Sci. (Med.), Prof., Chair of Surgery No. 1, School of Advanced Vocational Training and Retraining; Head of Endoscopy Unit No. 2, Ochapovsky Regional Clinical Hospital No. 1 Research Institute</p><p> </p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4255-0783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Будзинский</surname><given-names>C. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Budzinskiy</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Будзинский Станислав Александрович — доктор медицинских наук, старший научный сотрудник научно-исследовательской лаборатории хирургической гастроэнтерологии и эндоскопии при кафедре госпитальной хирургии № 2; врач-эндоскопист ГБУЗ «Городская клиническая больница № 31» Департамента здравоохранения г. Москвы</p><p>119415, г. Москва, ул. Лобачевского, д. 42</p></bio><bio xml:lang="en"><p>Stanislav A. Budzinskiy — Dr. Sci. (Med.), Senior Researcher, Research Laboratory of Surgical Gastroenterology and Endoscopy, Chair of Hospital Surgery No. 2, Faculty of General Medicine; Physician (endoscopy), City Clinical Hospital No. 31, Moscow City Department of Health</p><p> </p></bio><email xlink:type="simple">stanislav.budzinskiy@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1205-9152</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буриев</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Buriev</surname><given-names>I.  M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Буриев Илья Михайлович — доктор медицинских наук, профессор, советник главного врача, хирург </p><p> </p></bio><bio xml:lang="en"><p>Ilya M. Buriev — Dr. Sci. (Med.), Prof., Advisor to Chief Physician</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1467-5853</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вишневский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vishnevskiy</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вишневский Владимир Александрович — доктор медицинских наук, профессор, советник директора</p><p>117997, Москва, ул. Большая Серпуховская, д. 27</p></bio><bio xml:lang="en"><p>Vladimir A. Vishnevskiy — Dr. Sci. (Med.), Prof., Advisor to Director</p><p>117997, Moscow, Bolshaya Serpukhovskaya str., 27</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4255-0783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гальперин</surname><given-names>Э. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Galperin</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гальперин Эдуард Израилевич — доктор медицинских наук, профессор, почетный профессор и профессор кафедры госпитальной хирургии; почетный президент Международной общественной организации «Ассоциация хирургов-гепатологов»</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Eduard I. Galperin — Dr. Sci. (Med.), Prof., Professor Emeritus, Chair of Hospital Surgery; Honorary President, Association of Surgical Hepatologists NGO</p><p>119991, Moscow, Trubetskaya str., 8, bld. 2</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глабай</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Glabay</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Глабай Владимир Петрович — доктор медицинских наук, профессор кафедры хирургии </p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Vladimir P. Glabay — Dr. Sci. (Med.), Prof., Chair of Surgery</p><p>119991, Moscow, Trubetskaya str., 8, bld. 2</p></bio><email xlink:type="simple">glabay_v_p@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольцов</surname><given-names>В. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Goltsov</surname><given-names>V. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гольцов Валерий Ремирович — доктор медицинских наук, руководитель Городского панкреатологического центра, ведущий научный сотрудник отдела неотложной хирургии</p><p>192242, г. Санкт-Петербург, Будапештская ул., д. 3</p></bio><bio xml:lang="en"><p>Valeriy R. Goltsov — Dr. Sci. (Med.), Head of the City Centre for Pancreatology; Leading Researcher, Department of Emergency Surgery</p><p>192242, St. Petersburg, Budapeshtskaya str., 3</p></bio><email xlink:type="simple">govare@yandex.ru</email><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0573-7573</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дюжева</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyuzheva</surname><given-names>T. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дюжева Татьяна Геннадьевна — доктор медицинских наук, профессор кафедры госпитальной хирургии </p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Tatyana G. Dyuzheva — Dr. Sci. (Med.), Prof., Chair of Hospital Surgery</p><p>119991, Moscow, Trubetskaya str., 8, bld. 2</p></bio><email xlink:type="simple">dyuzheva_t_g@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9357-0998</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кармазановский</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Karmazanovskiy</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кармазановский Григорий Григорьевич — член-корреспондент РАН, доктор медицинских наук, профессор, заведующий отделением рентгенологии и магнитно-резонансных исследований с кабинетом ультразвуковой диагностики ; профессор кафедры лучевой диагностики и терапии медико-биологического факультета</p><p>117997, г. Москва, ул. Большая Серпуховская, д. 27</p></bio><bio xml:lang="en"><p>Grigoriy G. Karmazanovskiy — Dr. Sci. (Med.), Prof., Corresponding Member of the Russian Academy of Sciences, Head of the Department of Radiology and MRI with ultrasonic diagnostics unit; Prof., Chair of Diagnostic Radiology and Therapy, Faculty of Biomedicine</p><p>117997, Moscow, Bolshaya Serpukhovskaya str., 27</p></bio><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королев</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolev</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Королев Михаил Павлович — доктор медицинских наук, заведующий кафедрой общей хирургии с курсом эндоскопии; председатель Российского эндоскопического общества</p><p> 119014, г. Санкт-Петербург, Литейный проспект, д. 56</p><p> </p></bio><bio xml:lang="en"><p>Mikhail P. Korolev — Dr. Sci. (Med.), Head of the Chair of General Surgery with course of endoscopy; Chairman, Russian Endoscopic Society</p><p>119014, St. Petersburg, Liteynyy Ave., 56</p></bio><email xlink:type="simple">korolevmp@yandex.ru</email><xref ref-type="aff" rid="aff-11"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Красильников</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasilnikov</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Красильников Дмитрий Михайлович — доктор медицинских наук, профессор, заведующий кафедрой хирургических болезней № 1, руководитель хирургической клиники ГАУЗ РКБ МЗ РТ, руководитель хирургической клиники ГАУЗ «Республиканская клиническая больница» МЗ Республики Татарстан</p><p>420012, Казань, ул. Бутлерова, 49</p></bio><bio xml:lang="en"><p>Dmitriy M. Krasilnikov — Dr. Sci. (Med.), Prof., Head of Chair of Surgical Diseases No. 1; Director, Surgical Clinic, Republican Clinical Hospital</p><p>420012, Kazan, Butlerova str., 49</p></bio><xref ref-type="aff" rid="aff-12"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7760-2091</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучерявый</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucheryavy</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кучерявый Юрий Александрович — кандидат медицинских наук, заведующий гастроэнтерологическим отделением; научный руководитель образовательного проекта DiaGastro для врачей по вопросам гастроэнтерологии и смежных дисциплин агентства «Eventum Medical Consulting»</p><p>143421, Московская обл., г.о. Красногорск, д. Глухово, ул. Рублевское предместье, д. 2, к. 2.</p></bio><bio xml:lang="en"><p>Yuriy A. Kucheryavy — Cand. Sci. (Med.), Head of Gastroenterology Unit; Scientific Advisor, Eventum Medical Consulting Agency’s DiaGastro Education Programme for Physicians in Gastroenterology and Related Specialties</p><p>143421, Krasnogorsk, Glukhovo settl., Rublevskoe Predmestye str., 2, korp. 2</p></bio><email xlink:type="simple">proped@mail.ru</email><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6114-564X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maev</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маев Игорь Вениаминович — доктор медицинских наук, академик РАН, профессор, заведующий кафедрой пропедевтики внутренних болезней и гастроэнтерологии </p><p>127473, г. Москва, ул. Делегатская, д. 20, стр. 1</p></bio><bio xml:lang="en"><p>Igor V. Maev — Dr. Sci. (Med.), Prof., Full Member of the Russian Academy of Sciences, Head of the Chair of Internal Disease Propaedeutics and Gastroenterology</p><p>127473, Moscow, Delegatskaya str., 20, bld. 1</p></bio><email xlink:type="simple">igormaev@rambler.ru</email><xref ref-type="aff" rid="aff-14"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1405-7660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Майстренко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maystrenko</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Майстренко Николай Анатольевич — доктор медицинских наук, профессор, академик РАН, заведующий кафедрой факультетской хирургии им. С.П. Федорова</p><p>194044, г. Санкт-Петербург, ул. Академика Лебедева, 6</p></bio><bio xml:lang="en"><p>Nikolay A. Maystrenko — Dr. Sci. (Med.), Prof., Full Member of the Russian Academy of Sciences, Head of the Chair of Theoretical Surgery named after S.P. Fedorov</p><p>194044, St. Petersburg, Akademika Lebedeva str., 6</p></bio><xref ref-type="aff" rid="aff-15"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5156-2842</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипенко</surname><given-names>М. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipenko</surname><given-names>M. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Осипенко Марина Федоровна — доктор медицинских наук, профессор, заведующая кафедрой пропедевтики внутренних болезней</p><p>630091, г. Новосибирск, Красный проспект, д. 52</p></bio><bio xml:lang="en"><p>Marina F. Osipenko — Dr. Sci. (Med.), Prof., Head of the Chair of Internal Medicine Propaedeutics</p><p>630091, Novosibirsk, Krasnyy Ave., 52</p></bio><email xlink:type="simple">ngma@bk.ru</email><xref ref-type="aff" rid="aff-16"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2512-2760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прудков</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Prudkov</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прудков Михаил Иосифович — доктор медицинских наук, профессор, заведующий кафедрой хирургии, колопроктологии и эндоскопии</p><p> </p></bio><bio xml:lang="en"><p>Mikhail I. Prudkov — Dr. Sci. (Med.), Prof., Head of the Chair of Surgery, Coloproctology and Endoscopy</p><p> </p></bio><xref ref-type="aff" rid="aff-17"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1956-0070</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симаненков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Simanenkov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симаненков Владимир Ильич — доктор медицинских наук, профессор кафедры внутренних болезней, клинической фармакологии и нефрологии </p><p>191015, г. Санкт-Петербург, ул. Кирочная, д. 41</p></bio><bio xml:lang="en"><p>Vladimir I. Simanenkov — Dr. Sci. (Med.), Prof., Chair of Internal Medicine, Clinical Pharmacology and Nephrology</p><p>191015, St. Petersburg, Kirochnaya str., 41</p></bio><email xlink:type="simple">visimanenkov@mail.ru</email><xref ref-type="aff" rid="aff-18"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0794-232X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солоницин</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Solonitsin</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Солоницин Евгений Геннадьевич — кандидат медицинских наук, врач-эндоскопист, заведующий эндоскопическим отделением </p></bio><bio xml:lang="en"><p>Evgeniy G. Solonitsin — Cand. Sci. (Med.), Physician (endoscopy), Head of the Department of Endoscopy</p><p> </p></bio><xref ref-type="aff" rid="aff-19"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федоров Андрей Владимирович — доктор медицинских наук, профессор, главный научный сотрудник ФГБУ «Национальный медицинский исследовательский центр хирургии имени А.В. Вишневского» Министерства здравоохранения Российской Федерации; профессор кафедры эндоскопической хирургии </p><p> </p></bio><bio xml:lang="en"><p>Andrey V. Fedorov — Dr. Sci. (Med.), Prof., Principal Researcher; Prof., Chair of Surgical Endoscopy</p><p> </p></bio><xref ref-type="aff" rid="aff-20"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6036-7061</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федоров Евгений Дмитриевич — доктор медицинских наук, профессор, главный научный сотрудник кафедры госпитальной хирургии No 2 с научно-исследовательской лабораторией хирургической гастроэнтерологии и эндоскопии; клинический руководитель отделения эндоскопической хирургии </p><p>119415, г. Москва, ул. Лобачевского, д. 42</p></bio><bio xml:lang="en"><p>Evgeniy D. Fedorov — Dr. Sci. (Med.), Prof., Principal Researcher, Research Laboratory of Surgical Gastroenterology and Endoscopy, Chair of Hospital Surgery No. 2, Faculty of General Medicine; Clinical Director, Surgical Endoscopy Unit, City Clinical Hospital No. 31, Moscow City Department of Health</p><p>119415, Moscow, Lobachevskogo str., 42</p></bio><email xlink:type="simple">efedo@mail.ru</email><xref ref-type="aff" rid="aff-21"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0944-9811</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хлынов</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Khlynov</surname><given-names>I. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хлынов Игорь Борисович — доктор медицинских наук, доцент кафедры факультетской терапии и гериатрии; главный гастроэнтеролог Уральского федерального округа</p><p>620028, г. Екатеринбург, ул. Репина, д. 3</p></bio><bio xml:lang="en"><p>Igor B. Khlynov — Dr. Sci. (Med.), Assoc. Prof., Chair of Intermediate Therapy and Geriatrics; Chief Gastroenterologist, Ural Federal District</p><p>620028, Ekaterinburg, Repina str., 3</p></bio><email xlink:type="simple">hlinov.doc@yandex.ru</email><xref ref-type="aff" rid="aff-17"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0591-0535</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чикунова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chikunova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чикунова Марина Валерьевна — кандидат медицинских наук, доцент кафедры факультетской терапии и гериатрии </p><p>620028, г. Екатеринбург, ул. Репина, д. 3</p></bio><bio xml:lang="en"><p>Marina V. Chikunova — Cand. Sci. (Med.), Assoc. Prof., Chair of Intermediate Therapy and Geriatrics</p><p>620028, Ekaterinburg, Repina str., 3</p></bio><email xlink:type="simple">mvchikunova@mail.ru</email><xref ref-type="aff" rid="aff-17"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0522-0681</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабунин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabunin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шабунин Алексей Васильевич — доктор медицинских наук, профессор, член-корреспондент РАН, главный хирург Департамента здравоохранения г. Москвы; главный врач; заведующий кафедрой хирургии Российской медицинской академии непрерывного профессионального образования</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Aleksey V. Shabunin — Dr. Sci. (Med.), Prof., Corresponding Member of the Russian Academy of Sciences, Chief Surgeon, Moscow City Department of Health; Chief Physician, Botkin Hospital; Head of the Chair of Surgery, Russian Medical Academy of Continuous Professional Education</p><p>125284, Moscow, Vtoroy Botkinskiy proezd, 5</p></bio><email xlink:type="simple">glavbotkin@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-22"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1571-8125</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаповальянц</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shapovalyants</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шаповальянц Сергей Георгиевич — доктор медицинских наук, профессор, заведующий кафедрой госпитальной хирургии № 2 </p><p>119415, г. Москва, ул. 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(Med.), Prof., Chair of Internal Disease Propaedeutics, Gastroenterology and Hepatology</p><p>119435, Moscow, Pogodinskaya str., 1, bld. 1</p></bio><email xlink:type="simple">sheptulin_a_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-24"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8148-2862</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шифрин</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shifrin</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шифрин Олег Самуилович — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии</p><p>119435, г. Москва, ул. Погодинская, д. 1, стр. 1</p></bio><bio xml:lang="en"><p>Oleg S. Shifrin — Dr. Sci. 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Vishnevsky Institute of Surgery</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАOУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>N.I. Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО «Дальневосточный государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Far-Eastern State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» (Сеченовский Университет) Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Pavlov First Saint-Petersburg State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Kuban State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>ГБУЗ «Городская клиническая больница № 4» Департамента здравоохранения г. Москвы</institution></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 4, Moscow City Department of Health</institution></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр хирургии имени А.В. Вишневского» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>A.V. Vishnevsky Institute of Surgery</institution></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>ГБУ «Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе»</institution></aff><aff xml:lang="en"><institution>Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine</institution></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр хирургии имени А.В. Вишневского» Министерства здравоохранения Российской Федерации; ФГАOУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>A.V. Vishnevsky Institute of Surgery; N.I. Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>St. Petersburg State Paediatric Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-12"><aff xml:lang="ru"><institution>ФГАОУ ВО «Казанский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Kazan State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-13"><aff xml:lang="ru"><institution>АО «Ильинская больница»</institution></aff><aff xml:lang="en"><institution>Ilyinskaya Hospital JSC</institution></aff></aff-alternatives><aff-alternatives id="aff-14"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry</institution></aff></aff-alternatives><aff-alternatives id="aff-15"><aff xml:lang="ru"><institution>ФГБОУ ВО «Военно-медицинская академия им. С.М. Кирова» Министерства обороны Российской Федерации</institution></aff><aff xml:lang="en"><institution>S.M. Kirov Military Medical Academy</institution></aff></aff-alternatives><aff-alternatives id="aff-16"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-17"><aff xml:lang="ru"><institution>ФГБОУ ВО «Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Ural State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-18"><aff xml:lang="ru"><institution>ФБГОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Mechnikov North-Western State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-19"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр им. В.А. Алмазова»</institution></aff><aff xml:lang="en"><institution>V.A. Almazov National Medical Research Centre</institution></aff></aff-alternatives><aff-alternatives id="aff-20"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр хирургии имени А.В. Вишневского» Министерства здравоохранения Российской Федерации; ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>A.V. Vishnevsky Institute of Surgery; A.I. Yevdokimov Moscow State University of Medicine and Dentistry</institution></aff></aff-alternatives><aff-alternatives id="aff-21"><aff xml:lang="ru"><institution>ФГАOУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации; ГБУЗ «Городская клиническая больница № 31» Департамента здравоохранения г. Москвы</institution></aff><aff xml:lang="en"><institution>N.I. Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-22"><aff xml:lang="ru"><institution>ГБУЗ «Городская клиническая больница им. С.П. Боткина» Департамента здравоохранения г. Москвы</institution></aff><aff xml:lang="en"><institution>Botkin Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff-23"><aff xml:lang="ru"><institution>ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>N.I. Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-24"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный университет им. И.М. Сеченова»  (Сеченовский Университет) Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>15</day><month>05</month><year>2022</year></pub-date><volume>32</volume><issue>2</issue><fpage>99</fpage><lpage>156</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ивашкин В.Т., Кригер А.Г., Охлобыстин А.В., Анищенко М.А., Кардашева С.С., Алексеенко С.А., Багненко С.Ф., Быков М.И., Будзинский C.А., Буриев И.М., Вишневский В.А., Гальперин Э.И., Глабай В.П., Гольцов В.Р., Дюжева Т.Г., Кармазановский Г.Г., Королев М.П., Красильников Д.М., Кучерявый Ю.А., Маев И.В., Майстренко Н.А., Осипенко М.Ф., Прудков М.И., Симаненков В.И., Солоницин Е.Г., Федоров А.В., Федоров Е.Д., Хлынов И.Б., Чикунова М.В., Шабунин А.В., Шаповальянц С.Г., Шептулин А.А., Шифрин О.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ивашкин В.Т., Кригер А.Г., Охлобыстин А.В., Анищенко М.А., Кардашева С.С., Алексеенко С.А., Багненко С.Ф., Быков М.И., Будзинский C.А., Буриев И.М., Вишневский В.А., Гальперин Э.И., Глабай В.П., Гольцов В.Р., Дюжева Т.Г., Кармазановский Г.Г., Королев М.П., Красильников Д.М., Кучерявый Ю.А., Маев И.В., Майстренко Н.А., Осипенко М.Ф., Прудков М.И., Симаненков В.И., Солоницин Е.Г., Федоров А.В., Федоров Е.Д., Хлынов И.Б., Чикунова М.В., Шабунин А.В., Шаповальянц С.Г., Шептулин А.А., Шифрин О.С.</copyright-holder><copyright-holder xml:lang="en">Ivashkin V.T., Kriger A.G., Okhlobystin A.V., Anischenko M.A., Kardasheva S.S., Alekseenko S.A., Bagnenko S.F., Bykov M.I., Budzinskiy S.A., Buriev I.M., Vishnevskiy V.A., Galperin E.I., Glabay V.P., Goltsov V.R., Dyuzheva T.G., Karmazanovskiy G.G., Korolev M.P., Krasilnikov D.M., Kucheryavy Y.A., Maev I.V., Maystrenko N.A., Osipenko M.F., Prudkov M.I., Simanenkov V.I., Solonitsin E.G., Fedorov A.V., Fedorov E.D., Khlynov I.B., Chikunova M.V., Shabunin A.V., Shapovalyants S.G., Sheptulin A.A., Shifrin O.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/703">https://www.gastro-j.ru/jour/article/view/703</self-uri><abstract><sec><title>Цель</title><p>Цель: представить современные методы диагностики и лечения хронического панкреатита для врачей-гастроэнтерологов, врачей общей практики и врачей-терапевтов.</p></sec><sec><title>Основное содержание</title><p>Основное содержание. Хронический панкреатит (ХП) – длительное воспалительное заболевание поджелудочной железы, проявляющееся необратимыми морфологическими изменениями паренхимы и протоков органа, которые вызывают боль и/или стойкое снижение функции. Современные представления об этиологии ХП отражает классификация TIGAR-O. К критериям установления диагноза ХП относят характерные жалобы на приступы абдоминальной боли и/или клинические и лабораторные признаки экзокринной, эндокринной недостаточности при обязательном выявлении достоверных морфологических изменений (кальцификатов в паренхиме и камней в протоках поджелудочной железы, расширения главного панкреатического протока и его ветвей). КТ, МРХПГ и эндосонография панкреатобилиарной зоны рекомендуются как методы выбора для верификации диагноза ХП. Консервативное лечение пациентов с ХП направлено на купирование симптомов и предотвращение развития осложнений. Отдельные случаи с некупируемой болью в животе, а также осложненное течение заболевания (развитие протоковой гипертензии за счет вирзунголитиаза или стриктур протока ПЖ, механической желтухи, обусловленной компрессией холедоха, симптоматических постнекротических кист, портальной гипертензии за счет сдавления конфлюенса воротной вены или тромбоза селезеночной вены, стойкого нарушения пассажа пищи по двенадцатиперстной кишке, ложной аневризмы бассейна чревного ствола и верхней брыжеечной артерии) служат показанием к эндоскопическому или хирургическому лечению. В Рекомендациях представлены современные подходы к диагностике, консервативному, эндоскопическому и хирургическому лечению ХП, профилактике его осложнений.</p></sec><sec><title>Заключение</title><p>Заключение. Выполнение клинических рекомендаций может способствовать своевременному установлению диагноза и улучшению качества оказания медицинской помощи пациентам с хроническим панкреатитом.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: to present modern methods of diagnosis and treatment of chronic pancreatitis for gastroenterologists, general practitioners and physicians.</p><p>Chronic pancreatitis (CP) is a long-term inflammatory disease of the pancreas, manifested by irreversible morphological changes in the parenchyma and pancreatic ducts, which cause pain and/or persistent impairment of function. Current concept on the etiology of CP is reflected by the TIGAR-O classification. The criteria for establishing the diagnosis of CP include typical attacks of abdominal pain and/or clinical and laboratory signs of exocrine, endocrine insufficiency with the mandatory detection of characteristic morphological changes (calcifications in the parenchyma and pancreatic ductal stones, dilatation of the main pancreatic duct and its branches). CT, MRCP, and pancreatobiliary endosonography are recommended as the methods of choice to verify the diagnosis of CP. Conservative treatment of patients with CP is provided for symptom relief and prevention of complications. Individual cases with severe non-interactable abdominal pain, as well as a complicated course of the disease (development of ductal hypertension due to main pancreatic duct stones or strictures, obstructive jaundice caused by compression of the common bile duct, symptomatic postnecrotic cysts, portal hypertension due to compression of the portal vein or thrombosis of the splenic vein, persistent duodenal obstruction, pseudoaneurysm of the celiac trunk basin and the superior mesenteric artery) serve as an indication for endoscopic or surgical treatment. The Guidelines set out modern approaches to the diagnosis, conservative, endoscopic and surgical treatment of CP, and the prevention of its complications.</p></sec><sec><title>Conclusion</title><p>Conclusion. The implementation of clinical guidelines can contribute to the timely diagnosis and improve the quality of medical care for patients with chronic pancreatitis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>поджелудочная железа</kwd><kwd>хронический панкреатит</kwd><kwd>сахарный диабет</kwd><kwd>псевдокиста поджелудочной железы</kwd><kwd>панкреатическая гипертензия</kwd><kwd>эндоскопическое стентирование главного панкреатического протока</kwd><kwd>продольная панкреатикоеюностомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pancreas</kwd><kwd>chronic pancreatitis</kwd><kwd>diabetes mellitus</kwd><kwd>pancreatic pseudocyst</kwd><kwd>pancreatic hypertension</kwd><kwd>endoscopic stenting of the main pancreatic duct</kwd><kwd>lateral pancreatojejunostomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т. Горизонты клинической гастроэнтерологии. 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