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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22416/1382-4376-2023-33-6-7-15</article-id><article-id custom-type="elpub" pub-id-type="custom">gastro-j-887</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Воспалительные заболевания кишечника у детей: современные достижения  в диагностике и терапии</article-title><trans-title-group xml:lang="en"><trans-title>Inflammatory Bowel Diseases in Children: Modern Achievements in Diagnostics and Therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7308-7280</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkin</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хавкин Анатолий Ильич — доктор медицинских наук, профессор, заведующий кафедрой гастроэнтерологии и диетологии им. А.В. Мазурина, руководитель Московского областного центра детской гастроэнтерологии и гепатологии; профессор кафедры педиатрии с курсом детских хирургических болезней Медицинского института </p><p>115093, г. Москва, ул. Большая Серпуховская, 62</p></bio><bio xml:lang="en"><p>Anatoly I. Khavkin — Dr. Sci. (Med.), Professor, Head of the Department of Gastroenterology and Dietetics named after A.V. Mazurin, Head of the Moscow Regional Center of Pediatric Gastroenterology and Hepatology; Professor of the Department of Pediatrics with a Course in Pediatric Surgical Diseases, Medical Institute</p><p>115093, Moscow, Bolshaya Serpukhovskaya str., 62</p></bio><email xlink:type="simple">khavkin@nikid.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4733-3262</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Налетов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nalyotov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Налетов Андрей Васильевич — доктор медицинских наук, профессор, заведующий кафедрой педиатрии № 2 </p><p>283003, г. Донецк, просп. Ильича, 16</p></bio><bio xml:lang="en"><p>Andrew V. Nalyotov — Dr. Sci. (Med.), Professor, Head of the Department of Pediatrics No. 2</p><p>283003, Donetsk, Illicha avе., 16</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-7203-3775</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марченко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Marchenko</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марченко Наталия Александровна — ассистент кафедры педиатрии № 2 </p><p>283003, г. Донецк, просп. Ильича, 16</p></bio><bio xml:lang="en"><p>Nataliya A. Marchenko — Teaching Assistant of the Department of Pediatrics No. 2</p><p>283003, Donetsk, Illicha avе., 16</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ МО «Научно-исследовательский клинический институт детства» Министерства здравоохранения Московской области; ФГАОУ ВО «Белгородский государственный национальный исследовательский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Clinical Institute of Childhood of the Moscow Region; Belgorod National Research University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Донецкий государственный медицинский университет им. М. Горького» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Donetsk State Medical University name after M. Gorky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>02</day><month>12</month><year>2023</year></pub-date><volume>33</volume><issue>6</issue><fpage>7</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хавкин А.И., Налетов А.В., Марченко Н.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Хавкин А.И., Налетов А.В., Марченко Н.А.</copyright-holder><copyright-holder xml:lang="en">Khavkin A.I., Nalyotov A.V., Marchenko N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/887">https://www.gastro-j.ru/jour/article/view/887</self-uri><abstract><sec><title>Цель обзора литературы</title><p>Цель обзора литературы: осветить современные тенденции в диагностике и лечении воспалительных заболеваний кишечника у детей.</p></sec><sec><title>Основные положения</title><p>Основные положения. Заболеваемость воспалительными заболеваниями кишечника среди детей значительно выросла за последние три десятилетия, причем эти болезни часто характеризуются тяжелым течением. В то же время совершенствуются стратегии диагностики и лечения пациентов с этими заболеваниями желудочно-кишечного тракта: в качестве методов диагностики применяют эндоскопию высокого разрешения и видеокапсульную эндоскопию, определение фекального кальпротектина, внедряется биологическая терапия (инфликсимаб, адалимумаб, ведолизумаб и устекинумаб) и лекарственный мониторинг. Особое внимание уделяется роли диетических рекомендаций.</p></sec><sec><title>Заключение</title><p>Заключение. В настоящее время наблюдается значительный прогресс в диагностике и лечение воспалительных заболеваний кишечника у детей. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: to highlight current trends in the diagnosis and treatment of inflammatory bowel diseases in children.</p></sec><sec><title>Key points</title><p>Key points. The incidence of inflammatory bowel disease among children has increased significantly over the past three decades. Moreover, these diseases are often characterized by a severe course. At the same time, strategies for diagnosing and treating these patients are being improved: doctors began using high-definition endoscopy and video capsule endoscopy, the determination of fecal calprotectin, biological therapy (infliximab, adalimumab, vedolizumab, and ustekinumab) and drug monitoring. Particular attention is paid to the role of dietary recommendations.</p></sec><sec><title>Conclusion</title><p>Conclusion. Currently, there has been significant progress in the diagnosis and treatment of inflammatory bowel diseases in children.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>воспалительные заболевания кишечника</kwd><kwd>язвенный колит</kwd><kwd>болезнь Крона</kwd><kwd>фекальный кальпротектин</kwd><kwd>инфликсимаб</kwd><kwd>адалимумаб</kwd><kwd>ведолизумаб</kwd><kwd>устекинумаб</kwd></kwd-group><kwd-group xml:lang="en"><kwd>inflammatory bowel diseases</kwd><kwd>ulcerative colitis</kwd><kwd>Crohn's disease</kwd><kwd>fecal calprotectin</kwd><kwd>infliximab</kwd><kwd>adalimumab</kwd><kwd>vedolizumab</kwd><kwd>ustekinumab</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Graham D. B., Xavier R. J. Pathway paradigms revealed from the genetics of inflammatory bowel disease. Nature. 2020; 578: 527–39. 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