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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">gastro-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Gastroenterology, Hepatology, Coloproctology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1382-4376</issn><issn pub-type="epub">2658-6673</issn><publisher><publisher-name>«Gastro» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">gastro-j-993</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANG OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Современные аспекты диагноcтики и лечения инфекции H. pylori в свете профилактики рака желудка</article-title><trans-title-group xml:lang="en"><trans-title>Modern aspects of diagnostics and treatment of H. pylori infection from standpoint of stomach cancer prophylaxis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шептулин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheptulin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шептулин Аркадий Александрович — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней </p><p>119991, Москва, ул. Погодинская, д. 1, стр. 1. </p></bio><bio xml:lang="en"><p>Sheptulin Arkady A — MD, PhD, professor, Chair of internal diseases propedeutics, medical faculty</p><p>119991, Moscow, Pogodinskaya street, 1, bld 1. </p></bio><email xlink:type="simple">arkalshep@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лапина</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapina</surname><given-names>T. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university», Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>01</day><month>03</month><year>2015</year></pub-date><volume>25</volume><issue>1</issue><fpage>80</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шептулин А.А., Лапина Т.Л., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Шептулин А.А., Лапина Т.Л.</copyright-holder><copyright-holder xml:lang="en">Sheptulin A.A., Lapina T.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gastro-j.ru/jour/article/view/993">https://www.gastro-j.ru/jour/article/view/993</self-uri><abstract><p>Цель обзора. Обсудить современные аспекты диагностики и лечения инфекции H. pylori в свете профилактики рака желудка по итогам устных и стендовых докладов, представленных на XXVII Международном рабочем совещании Европейской группы по изучению Helicobacter.Основные положения. Основное внимание было уделено связи H. pylori с раком желудка и эрадикации инфекции как мере профилактики развития злокачественной патологии. Представлены данные о связи H. pylori с другими, в том числе и негастроэнтерологическими заболеваниями. Дана сравнительная оценка эффективности различных схем эрадикационной терапии. Согласно заключению большинства работ и данным мета-аналитических исследований, наиболее эффективными в настоящее время являются схемы квадротерапии с препаратами висмута и без них.Заключение. Для оценки роли инфекции H. pylori в развитии различных заболеваний, а также оптимизации лечения больных требуются дальнейшие исследования.</p></abstract><trans-abstract xml:lang="en"><sec><title>The aim of review</title><p>The aim of review. To discuss modern aspects of diagnostics and treatment of H. pylori infection in relation of stomach cancer prophylaxis according to data of oral and poster presentations, delivered at XXVII International workshop of the European Helicobacter Study Group.</p></sec><sec><title>Summary</title><p>Summary. The main attention has been given to relation of H. pylori infection to stomach cancer and eradications of infection as a mean of malignancy prevention. Data on relation of H. pylori to other diseases, including non-gastroenterological disorders are presented. Comparative estimation of efficacy of different modes of eradication therapy is given. According to conclusion of the majority of publications and data of meta-analyses, nowadays both bismuth-based and bismuth-free quadrotherapy are considered as the most effective treatment algorithms.</p></sec><sec><title>Conclusion</title><p>Conclusion. For estimation of role of H. pylori infection in development of various diseases, and to improve management of patients further studies are required.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>диагностика</kwd><kwd>профилактика</kwd><kwd>H. pylori</kwd><kwd>рак желудка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diagnostics</kwd><kwd>prophylaxis</kwd><kwd>H. pylori</kwd><kwd>stomach cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Varbanova M., Frauenschlager K., Langner S., Link A., Malfertheiner P. Active gastritis in Helicobacter pylori negative patients: A new entity? Helicobacter 2014; 19 (Suppl. 1):160.</mixed-citation><mixed-citation xml:lang="en">Varbanova M., Frauenschlager K., Langner S., Link A., Malfertheiner P. Active gastritis in Helicobacter pylori negative patients: A new entity? 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