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Autoimmune pancreatitis – the special form of chronic pancreatitis

Abstract

The aim of review. To present features of clinical presentation, diagnostics and treatment of special form of chronic pancreatitis – autoimmune pancreatitis (AIP).

Key points. The etiology of AIP is investigated insufficiently, the role of infection (in particular, viral), antigenic damage of pancreatic ducts and acinar cells is considered. AIP is frequently combined to other autoimmune diseases. The most typical serological marker of AIP is elevation of serum IgG4 level. Now 2 types of AIP are defined. AIP of the second type requires mandatory morphological confirmation. AIP is characterized by good treatment response by corticosteroids.

Conclusion. The issue of AIP remains actual and requires further studies.

About the Author

Ya. S. Tsimmerman
State educational state-funded institution of higher professional education «Wagner Perm state medical academy», Ministry of Healthcare of the Russian Federation
Russian Federation

Tsimmerman Yacob S. – Honored scientist of the Russian Federation, MD, PhD, professor of chair of faculty therapy

614990, Perm, Kuybyshev street, 39



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Review

For citations:


Tsimmerman Ya.S. Autoimmune pancreatitis – the special form of chronic pancreatitis. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2013;23(3):9-15. (In Russ.)

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