Лекарственные поражения печени (Часть 1-я)
Аннотация
Цель обзора. Осветить современные представления о механизмах лекарственного поражения печени (ЛПП), дать их классификацию, представить подходы к диагностике заболевания.
Основные положения. ЛПП могут протекать под маской всех известных острых и хронических заболеваний печени. Лекарства выступают одной из ведущих причин развития фульминантной печеночной недостаточности во многих странах мира. Ранняя диагностика и своевременная отмена препарата, вызывающего повреждение печени, позволяют предотвратить прогрессирование заболевания. В основе диагностики ЛПП лежит тщательный сбор лекарственного анамнеза, исключение других возможных причин поражения печени и применение диагностических шкал (CIOMS/RUCAM).
Заключение. Лекарственные поражения занимают значительное место в большом спектре заболеваний печени, своевременная диагностика этих поражений дает возможность исключить прием соответствующих препаратов.
Об авторе
С. Ф. Галимова
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздравсоцразвития РФ
Россия
Россия
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Рецензия
Для цитирования:
Галимова С.Ф. Лекарственные поражения печени (Часть 1-я). Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2012;22(3):38-48.
For citation:
Galimova S.F. Drug-induced liver injuries (Part 1). Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2012;22(3):38-48. (In Russ.)
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