Preview

Russian Journal of Gastroenterology, Hepatology, Coloproctology

Advanced search

Postcholecystectomy syndrome: the modern approach: resolution of Advisory council

https://doi.org/10.22416/1382-4376-2017-27-6-96-108

Abstract

Aim of publication. To present proceedings of Advisory council on postcholecystectomy syndrome (August 25, 2017; Prague, Czech Republic) with support of the Adamed Group company. Summary. The Advisory council proposed algorithm for investigation and management of patients with postcholecystectomy syndrome (PCS). Gallstone disease (GSD) is diagnosed in 10-25% of the population of various age, with obvious trend to involvement of the younger patient categories in the last decades. The total number of GSD patients increases every decade no less than twice. Cholecystectomy remains the basic method of surgical treatment of symptomatic GSD. Nowadays laparoscopic cholecystectomy became universally popular and earned the status of the «gold standard» of surgical treatment. At the same time at asymptomatic GSD the watchful waiting approach avoiding active treatment is considered to be the most expedient. Biliary sludge and microlithiasis including cases undiagnosed at routine investigation can be one of important factors for development of the PCS. Pharmacological treatment of sphincter of Oddi dysfunction that develop at GSD/PCS include following of dietary recommendations, intake of selective spasmolytics, digestive enzymes and ursodeoxycholic acid. Conclusions. Follow-up program for the patient of the cholecystectomy should include regular assessment of clinical symptoms for duly diagnostics of acute and/or severe complications and associated diseases, that may require surgical treatment. Treatment has to include regular courses of selective antispasmodics, the presence of indications - prescription of bile acid supplements, when required - methods of endoscopic surgery.

About the Authors

V. T. Ivashkin
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University
Russian Federation


A. V. Okhlobystin
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University
Russian Federation


D. S. Bordin
State government-financed healthcare institution of the Moscow Health Department «Loginov Moscow Clinical Scientific Center»
Russian Federation


E. Ya. Seleznyova
State government-financed healthcare institution of the Moscow Health Department «Loginov Moscow Clinical Scientific Center»
Russian Federation


Yu. A. Kucheryavy
State educational government-financed institution of higher professional education «Yevdokimov Moscow State University of Medicine and Dentistry»
Russian Federation


Ye. V. Bystrovskaya
State government-financed healthcare institution of the Moscow Health Department «Loginov Moscow Clinical Scientific Center»
Russian Federation


O. C. Vasnev
State government-financed healthcare institution of the Moscow Health Department «Loginov Moscow Clinical Scientific Center»
Russian Federation


M. F. Osipenko
State educational government-financed institution of higher professional education «Novosibirsk state medical university»
Russian Federation


G. H. Musayev
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University
Russian Federation


Yu. O. Shulpekova
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University
Russian Federation


References

1. Ивашкин В.Т., Лапина Т.Л., Баранская Е.К., Буеверов А.О., Буклис Э.Р., Гуревич К.Г. Рациональная фармакотерапия органов пищеварения: Руководство для практикующих врачей. М.: Литтерра; 2003. 1046 с.

2. Slattery S.A., Niaz O., Aziz Q., Ford A.C., Farmer A.D. Systematic review with meta-analysis: the prevalence of bile acid malabsorption in the irritable bowel syndrome with diarrhoea. Aliment Pharmacol Ther 2015;42(1):3-11. DOI:10.1111/apt.13227.

3. Abeysuriya V., Deen K.I., Navarathne N.M. Biliary microlithiasis, sludge, crystals, microcrystallization, and usefulness of assessment of nucleation time. Hepatobiliary Pancreat Dis Int 2010;9(3):248-53. http://www.ncbi. nlm.nih.gov/pubmed/20525550.

4. Takeda S., Aburada M. The choleretic mechanism of coumarin compounds and phenolic compounds. J pharmacobio-dynamics 1981;4(9):724-34. http://www. ncbi.nlm.nih.gov/pubmed/7334456.

5. Pickuth D., Spielmann R.P. Detection of choledocholithiasis: comparison of unenhanced spiral CT, US, and ERCP. Hepato-gastroenterology 2000;47(36):1514-7. http://www.ncbi.nlm.nih.gov/ pubmed/11148990.

6. Ивашкин В.Т., Шевченко В.П. Питание при болезнях органов пищеварения. Военно-мед журн 2006;327(1):54.

7. Stiehl A., Raedsch R., Czygan P., Gotz R., Manner C., Walker S. et al. Effects of biliary bile acid composition on biliary cholesterol saturation in gallstone patients treated with chenodeoxycholic acid and/or ursodeoxycholic acid. Gastroenterology 1980;79(6):1192-8. http://www.ncbi. nlm.nih.gov/pubmed/7439628.

8. Sandblom G., Videhult P., Crona Guterstam Y., Svenner A., Sadr-Azodi O. Mortality after a cholecystectomy: a population-based study. HPB: the official journal of the International Hepato Pancreato Biliary Association 2015;17(3):239-43. DOI:10.1111/ hpb.12356.

9. Agresta F., Campanile F.C., Vettoretto N., Silecchia G., Bergamini C., Maida P. et al. Laparoscopic cholecystectomy: consensus conference-based guidelines. Langenbeck’s archives of surgery. Dtsch Gesellschaft Chir 2015;400(4):429-53. DOI:10.1007/s00423-015-1300-4.

10. Finan K.R., Leeth R.R., Whitley B.M., Klapow J.C., Hawn M.T. Improvement in gastrointestinal symptoms and quality of life after cholecystectomy. Am J Surg 2006; 192(2):196-202. DOI:10.1016/j.amjsurg.2006.01.020.

11. Lien H.H., Huang C.C., Wang P.C., Huang C.S., Chen Y.H., Lin T.L. et al. Changes in quality-of-life following laparoscopic cholecystectomy in adult patients with cholelithiasis. J Gastrointestinal Surg: official journal of the Society for Surgery of the Alimentary Tract 2010;14(1):126-30. DOI:10.1007/s11605-009-1062-9.

12. Shi H.Y., Lee H.H., Tsai M.H., Chiu C.C., Uen Y.H., Lee K.T. Long-term outcomes of laparoscopic cholecystectomy: a prospective piecewise linear regression analysis. Surg Endosc 2011;25(7):2132-40. DOI:10.1007/ s00464-010-1508-x.

13. Moazeni-Bistgani M., Imani R. Bile bacteria of patients with cholelithiasis and theirs antibiogram. Acta medica Iranica 2013;51(11):779-83. http://www.ncbi.nlm.nih. gov/pubmed/24390947.

14. Ito K., Ito H., Whang E.E. Timing of cholecystectomy for biliary pancreatitis: do the data support current guidelines? J Gastrointestinal Surg: official journal of the Society for Surgery of the Alimentary Tract 2008;12(12):2164-70. DOI:10.1007/s11605-008-0603-y.

15. Fisher M., Spilias D.C., Tong L.K. Diarrhoea after laparoscopic cholecystectomy: incidence and main determinants. ANZ J Surg 2008;78(6):482-6. DOI:10.1111/j.1445-2197.2008.04539.x.

16. Venneman N.G., Besselink M.G., Keulemans Y.C., Vanberge-Henegouwen G.P., Boermeester M.A., Broeders I.A. et al. Ursodeoxycholic acid exerts no beneficial effect in patients with symptomatic gallstones awaiting cholecystectomy. Hepatology 2006;43(6):127683. DOI:10.1002/hep.21182.

17. Cotton P.B., Elta G.H., Carter C.R., Pasricha P.J., Corazziari E.S. Rome I.V. Gallbladder and Sphincter of Oddi Disorders. Gastroenterology 2016. DOI:10.1053/j. gastro.2016.02.033.

18. Yap L., Wycherley A.G., Morphett A.D., Toouli J. Acalculous biliary pain: cholecystectomy alleviates symptoms in patients with abnormal cholescintigraphy. Gastroenterology 1991;101(3):786-93. http://www.ncbi. nlm.nih.gov/pubmed/1860640.

19. Cotton P.B., Pauls Q., Keith J., Thornhill A., Drossman D., Williams A. et al. The EPISOD study: long-term outcomes. Gastrointestinal Endoscopy 2017. DOI:10.1016/j.gie.2017.04.015.

20. Bagaria D., Kaman L., Roger E., Dahyia D., Singh R., Bhattacharya A. Effect of laparoscopic cholecystectomy on gastric emptying and dyspepsia. Surg Endoscopy 2013;27(9):3116-20. DOI:10.1007/s00464-013-2838-2.

21. Shah Gilani S.N., Bass G.A., Kharytaniuk N., Downes M.R., Caffrey E.F., Tobbia I. et al. Gastroesophageal Mucosal Injury after Cholecystectomy: An Indication for Surveillance? J Am College Surg 2017;224(3):319-26. DOI:10.1016/j. jamcollsurg.2016.12.003.

22. Zhang J., Lu Q., Ren Y.F., Dong J., Mu Y.P., Lv Y. et al. Factors relevant to persistent upper abdominal pain after cholecystectomy. HPB: the official journal of the International Hepato Pancreato Biliary Association 2017;19(7):629-37. DOI:10.1016/j.hpb.2017.04.003.

23. Kirk G., Kennedy R., McKie L., Diamond T., Clements B. Preoperative symptoms of irritable bowel syndrome predict poor outcome after laparoscopic cholecystectomy. Surg Endosc 2011;25(10):3379-84. DOI:10.1007/s00464-011-1729-7.

24. Mertens M.C., De Vries J., Scholtes V.P., Jansen P., Roukema J.A. Prospective 6 weeks follow-up postcholecystectomy: the predictive value of pre-operative symptoms. J Gastrointestinal Surg: official journal of the Society for Surgery of the Alimentary Tract 2009;13(2):304-11. DOI:10.1007/s11605-008-0718-1.

25. Thistle J.L., Longstreth G.F., Romero Y., Arora A.S., Simonson J.A., Diehl N.N., et al. Factors that predict relief from upper abdominal pain after cholecystectomy. Clin gastroenterol hepatol: the official clinical practice journal of the American Gastroenterological Association 2011;9(10):891-6. DOI:10.1016/j.cgh.2011.05.014.

26. Roumm A.R., Pizzi L., Goldfarb N.I., Cohn H. Minimally invasive: minimally reimbursed? An examination of six laparoscopic surgical procedures. Surg Innovation 2005;12(3):261-87. DOI:10.1177/155335060501200313.

27. Feldman L.S., Kaneva P., Demyttenaere S., Carli F., Fried G.M., Mayo N.E. Validation of a physical activity questionnaire (CHAMPS) as an indicator of postoperative recovery after laparoscopic cholecystectomy. Surgery 2009;146(1):31-9. DOI:10.1016/j.surg.2009.02.019.

28. Wedlake L., A’Hern R., Russell D., Thomas K., Walters J.R., Andreyev H.J. Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 2009;30(7):707-17. DOI:10.1111/j.13652036.2009.04081.x.

29. Sung H.J., Paik C.N., Chung W.C., Lee K.M., Yang J.M., Choi M.G. Small Intestinal Bacterial Overgrowth Diagnosed by Glucose Hydrogen Breath Test in Post-cholecystectomy Patients. J Neurogastroenterol Motil 2015;21(4):545-51. DOI:10.5056/jnm15020.

30. Wanjura V., Sandblom G. How Do Quality-of-Life and Gastrointestinal Symptoms Differ Between Postcholecystectomy Patients and the Background Population? World J Surg 2016;40(1):81-8. DOI:10.1007/s00268-0153240-0.

31. Wei J.G., Wang Y.C., Liang G.M., Wang W., Chen B.Y., Xu J.K. et al. The study between the dynamics and the X-ray anatomy and regularizing effect of gallb.ladder on bile duct sphincter of the dog. World J Gastroenterol: WJG 2003;9(5):1014-9. http://www.ncbi. nlm.nih.gov/pubmed/12717848.


Review

For citations:


Ivashkin V.T., Okhlobystin A.V., Bordin D.S., Seleznyova E.Ya., Kucheryavy Yu.A., Bystrovskaya Ye.V., Vasnev O.C., Osipenko M.F., Musayev G.H., Shulpekova Yu.O. Postcholecystectomy syndrome: the modern approach: resolution of Advisory council. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2017;27(6):96-108. (In Russ.) https://doi.org/10.22416/1382-4376-2017-27-6-96-108

Views: 1307


ISSN 1382-4376 (Print)
ISSN 2658-6673 (Online)