Nosological aspects of hepatomegaly and splenomegaly at pediatric age
https://doi.org/10.22416/1382-4376-2016-26-1-54-58
Abstract
Aim of investigation. To estimate frequency of hepatomegaly and splenomegaly in pediatric patients, to determine their causes and nosological pattern of hepatolienal syndrome (HLS) in relation to age. Material and methods. Overall 5178 children aged 1 month to 17 years were examined to detect hepatosplenomegaly. Frequency of hepatomegaly and/or splenomegaly of unspecified etiology was analyzed with correlation to outpatient clinic admission rate and results of routine inspections. Results. The spectrum of age and main causes of hepatosplenomegaly was studied according to physical examination of 241 children. The most common causes of HLS include infectious diseases - 56 cases (23,2%) and neoplasms - 55 cases (22,8%; p<0,05). Diseases of blood, represented mostly by hemolytic anemias, were revealed in 28 (11,6%) children, metabolic diseases - in 17 cases (7,1%). In 25 (10,4%) patients somatic HLS-associated diseases, and 24 (10,0%) - other rare liver diseases were diagnosed. Extrahepatic portal hypertension syndrome was revealed in 8 (3,3%) patients. Conclusion. Nosological attribution of hepatomegaly and splenomegaly is determined by the age of child, there degree of organ enlargement, clinical and laboratory features of the main disease.
About the Authors
M. M. Kotovich
State educational government-financed institution of complementary professional education, Novokuznetsk state institute of postgraduate medicine, Ministry of healthcare of the Russian Federation, Novokuznetsk, Russia
Russian Federation
Russian Federation
F. K. Manerov
State educational government-financed institution of complementary professional education, Novokuznetsk state institute of postgraduate medicine, Ministry of healthcare of the Russian Federation, Novokuznetsk, Russia
Russian Federation
Russian Federation
E. V. Luchsheva
Municipal treatment-and-prophylactic institution «Zonal perinatal center», Novokuznetsk, Russia
Russian Federation
Russian Federation
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Review
For citations:
Kotovich M.M., Manerov F.K., Luchsheva E.V. Nosological aspects of hepatomegaly and splenomegaly at pediatric age. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2016;26(1):54-58. (In Russ.) https://doi.org/10.22416/1382-4376-2016-26-1-54-58
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