Preview

Russian Journal of Gastroenterology, Hepatology, Coloproctology

Advanced search

Prevalence of infection H. pylori in Moscow population

Abstract

Aim of investigation. To study the prevalence of H. pylori infection among able-bodied population of Moscow.

Material and methods. Diagnostics of Н. pylori infection was implemented at 863 working inhabitants of megacity. Antihelicobacter IgG antibodies were determined in blood serum by immunoenzyme method. In 264 persons with diagnosed Н. pylori infection antiCagA-antibodies were studied. Interview of 634 persons have been taken using original questionnaire by random sample.

Results. Extremely high prevalence of infection – 88% was found. Risk factors of infection among population of the town were revealed: age, poor education, bad living conditions (residing at hostel or in shared apartment), absence of the water drain and contact with sewage. No relation of infection prevalence to gender, drinking of non-boiled Moscow tap water and contact with domestic animals was marked.

Conclusion. Moscow falls into group of cities with extremely high Н.pylori-infection prevalence, with predominance of virulent bacteria strains. Risk factors of Н. pylori infection in megacity were revealed.

About the Authors

S. V. German
ГУ НИИ экологии человека и гигиены окружающей среды им. А.Н. Сысина РАМН
Russian Federation


I. Ye. Zykova
ГУ НИИ экологии человека и гигиены окружающей среды им. А.Н. Сысина РАМН
Russian Federation


A. V. Modestova
ГУ НИИ экологии человека и гигиены окружающей среды им. А.Н. Сысина РАМН
Russian Federation


N. V. Yermakov
ГУ НИИ экологии человека и гигиены окружающей среды им. А.Н. Сысина РАМН
Russian Federation


References

1. Ивашкин В.Т., Положенцев С.Д., Султанов В.К. и др. О патогенной роли Helicobacter pylori // Тер. арх. – 1993. – № 2. – С. 11–13.

2. Исаков В.А., Доморадский И.В. Хеликобактериоз. – М.: Медпрактика, 2003. – 411 с.

3. Калинин А.Д., Спесивцев В.Н., Скворцов С.В., Лыцарь Б.Н. Инфицированность Helicobacter pylori различных групп больных многопрофильного стационара и доноров крови // Клин. мед. – 1993. – № 3. – С. 38–39.

4. Курилович С.А., Решетников О.В., Шлыкова Л.Г. Некоторые итоги и перспективы изучения Helicobacter pylori-инфекции в Западной Сибири // Педиатрия. – 2002. – № 2 (приложение). – С. 65–71.

5. Abasivanik M.F., Tunc M., Salih B.A. Enzyme immunoassay and immunoblotting analysis of Helicobacter pylori infection in Turkish asymptomatic subjects // Diagn. Microbiol. Infect. Dis. – 2004. – Vol. 50, N 3. – P. 173–177.

6. Brown L.M. Helicobacter pylori: Epidemiology and routes of transmission // Epidemiol. Rev. – 2000. – Vol. 22. – P. 283–297.

7. Celinski K., Kurzeja-Miroslaw A., Slomka M. et al. The effects of environmental factors on the prevalence of Helicobacter pylori infection in inhabitants of Lublin province // Ann. Agric. Environ. Med. – 2006. – Vol. 13. – P. 185–191.

8. Crew K.D., Neugut A.I. Epidemioilogy of gastric cancer // World J. Gastroenterol. – 2006. – Vol. 12, N 3. – P. 354–362.

9. The EUROGAST Study Group. An international association between Helicobacter pylori infection and gastric cancer (no authors listed) // Lancet. – 1993. – Vol. 341, N 8861. – P. 1668.

10. Fan X.G., Chua A., Li T.G. et al. Survival of Helicobacter pylori in milk and tap water // J. Gastroenterol. Hepatol. – 1998. – Vol. 13, N 11. – P. 1096–1098.

11. Fawcett J.P., Barbezat G.O., Poulton R. et al. Helicobacter pylori serology in a birth cohort of New Zealanders from age 11 to 26 // World J. Gastroenterol. – 2005. – Vol. 11, N 21. – P. 3273–3276.

12. Friis L., Engstrand L., Edling C. Prevalence of Helico­bacter pylori infection among sewage workers // Scand. J. Work Environ. Health. – 1996. – Vol. 22. – P. 364–368.

13. Jeggli S., Steiner D., Joller H. et al. Hepatitis E. Helicobacter pylori? And gastrointestinal symptoms in workers exposed to waste water // Occup. Environ. Med. – 2004. – Vol. 61. – P. 622–627.

14. Jemal A., Thomas A., Murray T., Thun M. Cancer statistic, 2002 // CA Cancer J. Clin. – 2002. – Vol. 52. – P. 23–47.

15. Kato M., Asako M., Nakamura T. et al. Helicobacter pylori eradication prevents the development of gastric cancer – results of a long-term retrospective study in Japan // Aliment. Pharmacol. Ther. – 2006. – Vol. 24 (suppl. 4). – P. 203–206.

16. Kikuchi S., Yagyu K., Obata Y. et al. Serum pepsinogen values and Helicobacter pylori status among control subjects of a nested case-control study in JACC study // J. Epidemiol. – 2005. – Vol. 15. – N 5. – P. 197–204.

17. Kokkola A., Louhimo J., Puolakkainen P. Helicobacter pylori infection and low serum pepsinogen 1 level as risk factors for gastric carcinoma // World J. Gastroenterol. – 2005. – Vol. 21. – Vol. 11, N 7. – P. 1032–1036.

18. Mitipat N., Siripermpool P., Jadwattanakul T., Chaunt­hongkum S. The prevalence of Helicobacter pylori infection in patients with gastrointestinal symptoms in Chon Buri, Thailand // Southeast Asian J. Trop. Med. Public Health. – 2005. – Vol. 36, N 2. – P. 341–346.

19. Parkin D.M. International variation // Oncogene. – 2001. – Vol. 23. – P. 6329–6340.

20. Plonka M., Konturek P.C., Bielinski W. et al. Relationship between ghrelin and Helicobacter pylori infection in Polish adult shepherds and their children // Aliment. Pharmacol. Ther. – 2006. – Vol. 24 (suppl. 4). – P. 160–168.

21. Plummer M., Franceschi S., Munos N. Epidemiology of gastric cancer // IARC Sci. Publ. – 2004. – Vol. 157. – P. 311–326.

22. Shi R., Xu S., Zhang H. et al. Prevalence and risk factors for Helicobacter pylori infection in Chinese populations // Helicobacter. – 2008. – Vol. 13, N 2. – P. 157–165.

23. Sipponen P., Marshall B.J. Gastritis and gastric cancer. Western countries // Gastroenterol. Clin. North Am. – 2000. – Vol. 29. – P. 579–592.


Review

For citations:


German S.V., Zykova I.Ye., Modestova A.V., Yermakov N.V. Prevalence of infection H. pylori in Moscow population. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2010;20(2):25-30. (In Russ.)

Views: 68


ISSN 1382-4376 (Print)
ISSN 2658-6673 (Online)