Prevalence and risk factors of heartburn in organized population of administrative centre of Khakasia republic
Abstract
Aim of investigation. To analyze prevalence and risk factors of heartburn in organized population of administrative centre of Khakasia republic.
Material and methods. The epidemiologic screening diagnostics of gastroesophageal reflux disease was carried out by simultaneous (transverse) method at «Abakanvagonmash» enterprise in the city of Abakan at 1411 persons (506 native, 905 extraterrestrial) – the total scope was 93%. Results of clinical survey and interviewing were recorded in standard questionnaire of Mayo clinic for studying of heartburn.
Results. Prevalence of common heartburn was 31,4% in Caucasians and 25,5% — in Khakases, р=0,02, weekly heartburn – 14,7 and 10,3% respectively, р=0,02. In both ethnic groups studied scores were in direct relation to increase of age, excessive body weight and obesity. At Caucasians tobacco smoking abuse was a risk factor both in men (OR 3,25), and in women (OR 1,71). At Khakases only men (OR 2,79) showed this pattern, but not women (OR 1,31).
Conclusion. Ethnic features of clinical and epidemiologic characteristic of GERD were registered in studied populations.
About the Authors
N. N. ButorinRussian Federation
O. S. Rzhavicheva
Russian Federation
O. V. Khomenko
Russian Federation
O. V. Shtygashyeva
Russian Federation
V. V. Tsukanov
Russian Federation
References
1. Цуканов В.В., Хоменко О.В, Ржавичева О.С. Распространенность Helicobacter pylori и ГЭРБ у монголоидов и европеоидов Восточной Сибири // Рос. журн. гастроэнтерол. гепатол. колопроктол. – 2009. – Т. 19, N 3. – С. 38–41.
2. Dent J., El-Serag Н.В. Epidemiology of gastroesophageal reflux disease: a systematic review // Gut. – 2005. – Vol. 54, N 5. – P. 710–717.
3. El-Serag H.B., Ergun G.A., Pandolfino J., Fitzgerald S. Obesity increases esophageal acid exposure // Gut. – 2007. – Vol. 56, N 4. – P. 749–755.
4. Festi D., Scalio E., Baldi F. Body weight, lifestyle, dietary habits and gastroesophageal reflux disease // World J. Gastroenterology. – 2009. – Vol. 15, N 14. – Р. 1690–1701.
5. Fujiwara Y., Higuchi K., Iwakiri R. Differences in clinical characteristics between patients with endoscopy-negative reflux disease and erosive esophagitis in Japan // Am. J. Gastroenterol. – 2005. – Vol. 100, N 4. – Р. 754–758.
6. Fujiwara Y., Higuchi С., Iwakiri R. Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan // J. Gastroenterol. Hepatol. – 2005. – Vol. 20, N 1. – P. 26–29.
7. Jacobson B.C., Somers S.C., Horbach P., Sander S. Body-mass index and symptoms of gastroesophageal reflux in women // N. Engl. J. Med. – 2006. – Vol. 354, N 7. – P. 2340–2348.
8. Jennifer H., Michael N., Eden P., Thronhill J. Gastroesophageal reflux disease (GERD) treatment patterns and economic outcomes in a managed care population // Am. J. Gastroenterol. – 2000. – Vol. 95, N 7. – Р. 2630.
9. Kahrilas P.J. Gastroesophageal reflux disease // N. Engl. J. Med. – 2008. – Vol. 359, N 5. – Р. 1700–1707.
10. Kaltenbach T., Crockett S. Are lifestyle measures effective in patients with gastroesophageal reflux disease?: an evidence-based approach // Arch. Intern. Med. – 2006. – Vol. 166, N 9. – Р. 965–971.
11. Kang J.Y. Systematic review: geographical and ethnic differences in gastroesophageal reflux disease // Aliment. Pharmacol. Ther. 2004. – Vol. 20, N 7. – Р. 705–717.
12. Kim N., Lee S.W., Cho S.E. The prevalence of GERD and risk factors for erosive esophagitis and non-erosive reflux disease: a nationwide multicentre prospective study in Korea // Aliment. Pharmacol. Ther. – 2008. – Vol. 27, N 2. – Р. 173–185.
13. Labenz J., Jaspersen D., Kulig M. Risk factors for erosive esophagitis: a multivariate analysis based on the ProGERD study initiative // Am. J. Gastroenterol. – 2004. – Vol. 99, N 9. – Р. 1652–1656.
14. Locke G.R., Talley N.J., Fett S.L. A new questionnaire for gastroesophageal reflux disease // Mayo Clin. Proc. – 1994. – Vol. 69, N 3. – P. 539–547.
15. Murray L., Johnston B., Lane H., Hasrey I. Relationship between body mass and gastroesophageal reflux symptoms: The Bristol Helicobacter project // Int. J. Epidemiol. 2003. – Vol. 32, N 5. – Р. 645–650.
16. Nandurkar S., Locke G.R., Fett S.L. Relationship between body mass index, diet, exercise and gastroesophageal reflux symptoms in a community // Aliment. Pharmacol. Ther. – 2004. – Vol. 20, N 5. – Р. 497–505.
17. Nilsson M., Johnsen R, Ye W., Hveem K. Lifestyle related risk factors in the aetiology of gastroesophageal reflux // Gut. – 2004. – Vol. 53, N 12. – Р. 1730–1735.
18. Nocon M., Labenz J., Jaspersen D. Association of body mass index with heartburn, regurgitation and esophagitis: results of the progression of gastroesophageal reflux disease study // J. Gastroenterol. Hepatol. – 2007. – Vol. 22, N 12. – P. 1728–1731.
19. Ruigomez A., Wallander M.A., Johanson S., Graffner H. Natural history of gastroesophageal reflux disease diagnosed in UK general practice // Aliment. Pharmacol. Ther. – 2004. – Vol. 20, N 7. – Р. 751–760.
20. Tack J., Talley N.J., Stanghellini V. Functional gastroduodenal disorders // Gastroenterology. – 2006. – Vol. 130, N 5. – P. 1466–1479.
21. Talley N.J., Howell S., Poulton R. Obesity and chronic gastrointestinal tract symptoms in young adults: a birth cohort study // Am. J. Gastroenterol. – 2004. – Vol. 99, N 9. – P. 1807–1814.
22. Vakil N., van Zanden S.V., Kahrilas P. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterol. – 2006. – Vol. 101, N 8. – P. 1900–1920.
Review
For citations:
Butorin N.N., Rzhavicheva O.S., Khomenko O.V., Shtygashyeva O.V., Tsukanov V.V. Prevalence and risk factors of heartburn in organized population of administrative centre of Khakasia republic. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2010;20(2):39-43. (In Russ.)
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