Low-Grade Appendiceal Mucinous Neoplasms: Description of Two Cases and Literature Review

Aim: to present two clinical cases of low-grade appendiceal mucinous neoplasms (LAMN) and evaluate the oncological adequacy of ileocecectomy with ileoascending anastomosis in patients with cecal involvement.

Key points. Appendiceal mucinous neoplasms are rare tumors detected either during radiological examinations conducted for other reasons, intraoperatively in patients operated on with a diagnosis of appendicitis, or during histopathological examination of the appendectomy specimen. In 2025, two male patients, aged 36 and 70 years, with the aforementioned diagnosis were operated on at the Oncology Clinic of Azerbaijan Medical University. The neoplasm in the 36-year-old patient was discovered during intraoperative revision for suspected appendicitis at a district hospital. In the other patient, the tumor was detected preoperatively during a CT scan performed to stage an endoscopically and histopathologically confirmed sigmoid colon carcinoma. Both patients underwent an ileocecectomy with an ileoascending anastomosis for the appendiceal mucinous neoplasms. The postoperative period was uneventful, and histopathological examination of the resected specimens confirmed a low-grade appendiceal mucinous neoplasm (LAMN) in both cases.

Conclusion. In patients with LAMN adherent to or infiltrating the cecum, an ileocecectomy with ileoascending anastomosis can be performed as an adequate surgical procedure. Although this volume of surgery is less extensive than a right hemicolectomy, it can theoretically be compared with it in terms of providing oncological radicality.

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