Atypical lymphogranulomatosis or typical ANCA-associated vasculitis with liver and intestinal involvement?
Abstract
Aim of investigation. To demonstrate complexity of differential diagnostics of granulomatous diseases clinical forms.
Stuff and methods. Article presents a case of disease with fatal course, which leading signs included longstanding intermittent fever, granulomatous pulmonary lesion, cholestatic granulomatous lesion of the liver, nephrotic syndrome, ischemic lesion of intestine. Differential diagnosis was carried out between ANCAassociated vasculitis, primary sclerosing cholangitis and lymphogranulomatosis.
Results. Morphological analysis of the autopsy samples give ground to conclude, that patient had combination of two diseases: lymphogranulomatosis and systemic vasculitis. However, the literature review devoted to ANCA-associated vasculites, and features of clinical course entitle doubts and reflections.
About the Authors
Ye. A. LukinaRussian Federation
Ye. P. Sysoyeva
Russian Federation
G. A. Sukhanova
Russian Federation
G. M. Galstyan
Russian Federation
A. V. Grzhimolovsky
Russian Federation
S. R. Karagulyan
Russian Federation
G. A. Frank
Russian Federation
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Review
For citations:
Lukina Ye.A., Sysoyeva Ye.P., Sukhanova G.A., Galstyan G.M., Grzhimolovsky A.V., Karagulyan S.R., Frank G.A. Atypical lymphogranulomatosis or typical ANCA-associated vasculitis with liver and intestinal involvement? Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2008;18(5):71-79. (In Russ.)
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