Modern treatment methods of patients with liver metastases of colorectal cancer
Abstract
Aim of investigation. Efficacy of the modern methods of treatment of liver metastases of colorectal cancer was estimated.
Material and methods. Overall 117 patients have been included in the study with isolated metastatic liver involvement. Efficacy of liver resection, radio-frequency ablation (RFA), systemic and intra-arterial hepatic chemotherapy (IAHC) was studied.
Results. The five-years general survival rate at liver resection was 33,3%, relapse-free – 22,2%, at RFA – 16,2 and 13,5% respectively. HACE allows to achieve higher rate of positive response, not increasing risk of generalization of process, but does not improve scores of remote survival rate in comparison to systemic chemotherapy.
Conclusions. The most effective treatment method, allowing to achieve 33% of 5-year survival, is liver resection.
About the Authors
Ye. N. Grebenkin
Federal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian Federation
Russian Federation
Russian Federation
V. D. Chhikvadze
Federal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian Federation
Russian Federation
Russian Federation
U. S. Stanoyevich
Federal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian Federation
Russian Federation
Russian Federation
Ye. I. Dekhissi
Federal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Grebenkin Ye.N., Chhikvadze V.D., Stanoyevich U.S., Dekhissi Ye.I. Modern treatment methods of patients with liver metastases of colorectal cancer. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2013;23(3):28-32. (In Russ.)
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