The prevalence of atrophic gastritis of the body of stomach at Krasnoyarsk population over 45 years old
Abstract
Aim of investigation. To determine prevalence of atrophic gastritis of body of the stomach at Krasnoyarsk population over 45 years old.
Material and methods. Level of pepsinogen-1, pepsinogen-2 and presence of anti-Helicobacter pylori antibodies in blood serum was determined by «Gastropanel» test-system («Biohit», Finland). Original study was carried out with involvement of 387 men and 414 women over 45 years of age (n=801), selected as a random sample, and 29 relatives of stomach cancer patients.
Results. The prevalence of severe atrophic gastritis of the body of stomach, revealed by contents of pepsinogen-1 and pepsinogen-2, as well as pepsinogen-1/ pepsinogen-2 ratio under 3,0, was 10,9% (in males — 11,9%, in females — 9,9%). H. pylori infection was revealed in 90,0% of patients. Age of 55 years and older was a risk factor for severe atrophic gastritis.
Conclusions. Serological assessment of pepsinogen-1, pepsinogen-2 and H. pylori infection is effictove method of atrophic gastritis diagnostics.
About the Authors
V. V. TsukanovRussian Federation
O. V. Tret'yakova
Russian Federation
O. S. Amelchugova
Russian Federation
E. V. Kasparov
Russian Federation
D. V. Rodina
Russian Federation
A. V. Vasyutin
Russian Federation
N. N. Butorin
Russian Federation
Yu. L. Tonkikh
Russian Federation
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Review
For citations:
Tsukanov V.V., Tret'yakova O.V., Amelchugova O.S., Kasparov E.V., Rodina D.V., Vasyutin A.V., Butorin N.N., Tonkikh Yu.L. The prevalence of atrophic gastritis of the body of stomach at Krasnoyarsk population over 45 years old. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2012;22(4):27-31. (In Russ.)
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