Potentials of virtual colonoscopy in screening of colorectal cancer and adenomatous polyps
Abstract
Aim of investigation. Assessment of capability of virtual colonoscopy (VCS) in revealing of neoplasms of the large intestine and representation of it as a probable method for screening diagnostics colorectal cancer (CRC).
Material and methods. Original study have included 148 patients in the age of 2 to 82 years. Indications for VCS were: complaints of change of a normal bowel habit, positive test for tumor markers, positive fecal occult blood test.
Results. Overall 85 mass lesions have been revealed at VCS, of which 12 appeared to be colorectal cancer, the other 73 – polyps. The smallest polyp was 4 mm in size. Sensitivity of VCS in comparison to endoscopic colonoscopy in revealing of mass lesions was 93%, specificity – 78%.
Conclusions. This procedure is indicated at incomplete or contraindicated endoscopic colonoscopy, studying of prestenotic regions of intestine, at children for revealing anomalies of development. VCS can be recommended for screening programs of diagnostics of diseases of the large intestine.
About the Authors
Ye. Yu. KhomutovaRussian Federation
Yu. T. Ignat’yev
Russian Federation
V. L. Poluektov
Russian Federation
Yu. G. Filippova
Russian Federation
References
1. Секачева М.И., Ивашкин В.Т. Скрининг колоректального рака в России // Рос. журн. гастроэнтерол. гепатол. колопроктол. – 2003. – Т. 13, № 4. – С. 44–49.
2. Хомутова Е.Ю. и др. Устройство для раздувания толстой кишки / Патент на полезную модель № 71072 от 14.05.2007 г.
3. Хомутова Е.Ю., Игнатьев Ю.Т. Мультиспиральная компьютерная виртуальная колоноскопия в диагностике патологии толстой кишки (Обзор литературы) // Медицинская визуализация. – 2008. – № 6. – С. 73.
4. Bond J. Clinical evidence for the adenoma-carcinoma sequence, and the management of patients with colorectal adenomas // Semin. Gastrointest. Dis. – 2000. – N 11. – P. 176–184.
5. Fletcher R.H. Colorectal cancer screening on stronger footing // N. Engl. J. Med. – 2008. – Vol. 359, N 12. – P. 1285–1288
6. Atlas of gastrointestinal imaging radiologic-endoscopic correlation / Eds. P.J. Pickhardt, G.M. Arluk. – Philadelphia, PA: Saunders Elsevier. – 2007. – 512 p.
7. Sahni V., Burling D. The new NHS colorectal cancer screening programme and the potential role of radiology? // Br. J. Radiol. – 2007. – Vol. 80 (958). – P. 778–781.
8. Virtual colonoscopy: A practical guide / Eds. P. Lefere, S. Gryspeerdt. – Paris: Springer, 2005. – 204 p.
9. Yee J. Virtual colonoscopy / Ed. G. Galdino. – 2008. – 219 p.
Review
For citations:
Khomutova Ye.Yu., Ignat’yev Yu.T., Poluektov V.L., Filippova Yu.G. Potentials of virtual colonoscopy in screening of colorectal cancer and adenomatous polyps. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2009;19(6):49-54. (In Russ.)
Views:
15
Email this article 
