Systemic manifestations of chronic inflammatory bowel diseases in children
Abstract
The aim of review. To present clinical pattern, methods of diagnostics and approaches to treatment of systemic manifestations of inflammatory bowel diseases (IBD) in children.
Original positions. Extraintestinal manifestations are present in 25–60% of patients of IBD – over 40% of patients with Crohn’s disease (CD) and is much rare in patients with ulcerative colitis (UC). At comparison of frequency of extraintestinal manifestations of UC and CD at children and adults appeared, that children have less often lesions of joints (13% at CD and 7% at UC vs. 28 and 26% in adults), eyes (less than 1% at CD and UC vs. 4% at UC in adults), skin (7% at CD and 1% at UC vs. 14 and 19% at adults). Clinical case of 10 years-old child with ulcerative colitis in whom disease was manifested by joint lesions that considerably complicated diagnostics is presented.
Conclusion. Correct treatment of extraintestinal signs promotes well-timed establishment of the IBD diagnosis and prescription of adequate treatment at possible atypical variant of disease that allows to achieve sustained remission, to avoid complications and prevents development of treatment resistance.
About the Authors
B. O. MatsukatovaRussian Federation
S. I. Erdes
Russian Federation
M. A. Ratnikova
Russian Federation
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Review
For citations:
Matsukatova B.O., Erdes S.I., Ratnikova M.A. Systemic manifestations of chronic inflammatory bowel diseases in children. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2009;19(2):65-69. (In Russ.)
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