Total mesorectumectomy in organ-preserving surgery of rectal cancer (experimental and clinical investigation)
Abstract
Aim of investigation. Improvement of functional, long-term results of treatment and quality of life of patients with mid-ampullar rectal cancer by substantiation and development of method of low anterior resection (LAR) of rectum with total mesorectumectomy (TME).
Methods. The experimental investigation stage included series conducted on non-purebred dogs. In clinic 33 patients underwent surgery according to original method. Results. Adequacy of blood supply to rectum stump by aa. rectales caudales after simultaneous switching off a. rectalis cranialis and aa. rectales mediales at TME was detected. In clinical practice it was possible to decrease frequency of locoregional relapses of cancer from 30,8±9,2% in control group to 9,4±5,2% – in the main group (р<0,05) and to increase number of patients with 5-year relapse-free survival rate from 42,3±9,9 to 71,9±8,0% respectively (р><0,05). Conclusions. Developed LAR method with TME has allowed to improve function and long-term results of treatment, as well as the quality of life of patients with cancer of mid-ampullar region of the rectum>< 0,05) and to increase number of patients with 5-year relapse-free survival rate from 42,3±9,9 to 71,9±8,0% respectively (р<0,05).
Conclusions. Developed LAR method with TME has allowed to improve function and long-term results of treatment, as well as the quality of life of patients with cancer of mid-ampullar region of the rectum.
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Review
For citations:
Khozhayev A.A. Total mesorectumectomy in organ-preserving surgery of rectal cancer (experimental and clinical investigation). Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2008;18(1):56-58. (In Russ.)
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