Infection Helicobacter pylori and stomach cancer: state-of-the-art
Abstract
The aim of review. To carry out analysis of the publications devoted to Helicobacter pylori infection and stomach cancer (SC) interrelation.
Original positions. Available data convincingly confirm that Н. pylori infection increases risk of SC development, however in close interaction with host factors – genetic factors, dietary habits, etc. Eradication of Н. pylori results in decrease of atrophic gastritis severity, but does not affect intestinal metaplasia process. Nowadays it is indicated for patients with high risk of SC (having atrophic gastritis, postgastrectomy patients for early SC, first-degree relatives of patients with SC).
Conclusion. Pathophysiological and clinical aspects of interrelations between Н. pylori infection and SC require the further studies.
About the Author
A. A. Sheptulin
Первый Московский государственный
медицинский университет им. И.М. Сеченова
Russian Federation
Russian Federation
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Review
For citations:
Sheptulin A.A. Infection Helicobacter pylori and stomach cancer: state-of-the-art. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2012;22(2):77-82. (In Russ.)
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