Инфекция Helicobacter pylori и рак желудка: современное состояние проблемы
Аннотация
Цель обзора. Провести анализ публикаций, посвященных проблеме взаимосвязи инфекции Helicobacter pylori и рака желудка (РЖ).
Основные положения. Имеющиеся данные убедительно подтверждают, что инфекция Н. pylori повышает риск развития РЖ, однако в тесном взаимодействии с факторами макроорганизма – генетическими, особенностями питания и др. Эрадикация Н. pylori приводит к уменьшению выраженности атрофического гастрита, но не влияет на процессы кишечной метаплазии. В настоящее время ее проведение показано пациентам с высоким риском развития РЖ (с атрофическим гастритом, после резекций по поводу раннего РЖ, родственникам больных РЖ первой степени родства).
Заключение. Патофизиологические и клинические аспекты взаимоотношений между инфекцией Н. pylori и РЖ требуют дальнейших исследований.
Об авторе
А. А. Шептулин
Первый Московский государственный
медицинский университет им. И.М. Сеченова
Россия
Россия
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Рецензия
Для цитирования:
Шептулин А.А. Инфекция Helicobacter pylori и рак желудка: современное состояние проблемы. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2012;22(2):77-82.
For citation:
Sheptulin A.A. Infection Helicobacter pylori and stomach cancer: state-of-the-art. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2012;22(2):77-82. (In Russ.)
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