Peutz–Jeghers syndrome: review of the literature and clinical case presentation
Abstract
The aim of publication. To show complexities of diagnostics and treatment at hereditary multiple gastrointestinal polyposis by the example of clinical case.
Features of clinical case. At the patient with PeutzJeghers syndrome, despite of well-timed diagnosis, annual screening and treatment, it was not possible to avoid development of serious complications. Recurrent bleedings from polyps and intestinal obstruction became the cause of four extensive resections of the small and large intestine that resulted in development of short bowel syndrome and disability of the patient.
Conclusion. Now there is no pathogenically proved treatment of Peutz-Jeghers syndrome. The main management approach consists in dynamic observation and the prevention of fatal complications.
About the Authors
V. O. Kaybysheva
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
V. T. Ivashkin
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
Ye. K. Baranskaya
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
O. S. Shifrin
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
K. V. Pyurveyeva
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
A. Ye. Leonovich
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
O. A. Sklyanskaya
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
A. A. Sheptulin
ГОУ ВПО «1-й Московский государственный медицинский университет им. И.М. Сеченова Росздрава»
Russian Federation
Russian Federation
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Review
For citations:
Kaybysheva V.O., Ivashkin V.T., Baranskaya Ye.K., Shifrin O.S., Pyurveyeva K.V., Leonovich A.Ye., Sklyanskaya O.A., Sheptulin A.A. Peutz–Jeghers syndrome: review of the literature and clinical case presentation. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2011;21(2):54-61. (In Russ.)
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