Clinical features of chronic pancreatitis at elderly patients with severe mesenteric atherosclerosis
Abstract
Aim of investigation. To study clinical features of chronic pancreatitis in patients with severe mesenteric atherosclerosis (calcification of celiac trunk).
Material and methods. Overall 290 patients with chronic pancreatitis have been investigated. According to alcoholic and biliary etiology of disease, signs that was revealed at computer tomography with bolus contrast injection (calcification of ostium of celiac trunk and superior mesenteric artery), 43 patients were selected to the group with «ischemic component».
Results. Patients of this group were characterized by series of features: older age, lower intensity of pain, higher frequency of ischemic heart disease and systemic hypertension. Gastroduodenal erosions with relative resistance to drug treatment were more frequently diagnosed in these patients.
Conclusion. At elderly patients with chronic pancreatitis and calcification of mesenteric blood vessels, with respect to frequent constipation tablet pancreatin agents (Mezym® 10000) have high efficacy in treatment of abdominal pain.
About the Authors
O. S. ShifrinRussian Federation
I. A. Sokolina
Russian Federation
T. L. Lemina
Russian Federation
References
1. Гастроэнтерология «Национальное руководство» / Под. ред. В.Т. Ивашкина, Т.Л. Лапиной. – М.: «ГЭОТАРМЕДИА», 2008. – 700 с.
2. Рациональная фармакотерапия заболеваний органов пищеварения / Под общей ред. В.Т. Ивашкина, Т.Н. Лапиной. – М.: Литерра, 2006. – С. 205–258.
3. Савельев В.С. Петухов В.А. Бычков С.Г. и др. Нарушения микроциркуляции при хронической ишемической болезни органов пищеварения и дислипопротеидемии // Грудн. и сердечно-сосуд. хирургия. – 1999. – № 4. – С. 40–45.
4. Bourliere M., Barthet M., Berthezene P. еt al. Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis? // Gut. – 1991. – Vol. 32. – P. 1392–1395.
5. Busquet J. Intravascular stenting in the superior mesenteric artery of chronic abdominal angina // J. Endovass. Surg. – 1997. – Vol. 4, N 4. – P. 380–384.
6. Cappeller W.A., Kettmann R., Behrmann C. Surgical therapy of chronic visceral arterial ischemia with aortoceliac, mesenteric patch bypass // Chirurg. – 1998. – Vol.69. – P. 6422–6649.
7. Clowdhury P., Bone R.C., Louria D.B., Rayford P.L. Effect of cigarette smoke on human serum inhibitory capacity and antitripsin concentration // Rev. Respir. Dis. – 1982. – Vol. 126. – P. 177–179.
8. Foitsik T., Buhr H.J. New aspects in the pathophysiology of chronic pancreatitis // Chirurg. – 1997. – Vol. 68, N 9. – P. 855–864.
9. Fortson M.R., Freedman S.N., Webster B.D. Clinical assessment of hyperlipidemic pancreatitis // Am. J. Gastroenterol. – 1995. – Vol. 90. – P. 2134–2139.
10. Hamed R.V., Ghanduor T.N. Abdominal angina and intestinal gangrene – a catastrophic presentation of arterial fibromuscular dysplasia case report and review of the literature // J. Pediatr. Surg. – 1997. – Vol. 32, N 9. – P. 1379–1380.
11. Harward T.R., Weiborn M.B., Martin T.D. et al. Visceral ischemia and organ dysfunction after thoracoabdominal aortic aneurism repair. A clinical and cost analisis // Ann. Surg. – 1996. – Vol. 223. – P. 729–734.
12. Levy P., Mathurin P., Rogueplo A. et al. A multidimensional case control study of dietary alcohol and tobacco habits in alcoholic men with chronic pancreatitis // Pancreas. – 1995. – P. 106231–106238.
13. Pitchumoni C.S. Role of nutrition in chronic pancreatitis // Chronic Pancreatitis / Eds. H. Beger, M. Buchler, H. Ditschuneit, P. Malfertheiner. – Berlin: Heidelberg Springer-Ferlag, 1990. – P. 15–25.
14. Toskes P.P. Hyperlipidemic pancreatitis // Gastroenterol. Clin. North Am. – 1990. – Vol. 19, N 4. – P. 783–791.
Review
For citations:
Shifrin O.S., Sokolina I.A., Lemina T.L. Clinical features of chronic pancreatitis at elderly patients with severe mesenteric atherosclerosis. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2011;21(3):35-40. (In Russ.)
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