Optimization of preparation for colonoscopy by application of the enteral form of dulcolax
Abstract
Aim of investigation. Evaluation of potentials of «dulcolax» for preparation for colonoscopy.
Material and methods. Preparation for colonoscopy at versatile hospital was applied by oral intake of macrogol-based preparation (2–2,5 l of solution) in combination to 20 mg of bisacodyl (dulcolax) in 50 patients. Patients of comparison group received a full dose of macrogol (4 l).
Results. Preparation quality in clearing of intestine appeared to be comparable in the main and control groups. At the same time patients of a basic group less often had unpleasant symptoms and they had no adverse effects related to intake of main laxative.
Conclusion. Dulcolax can be used as additional agent in preparation for colonoscopy to minimize adverse effects related to this procedure, and improvement of its end result.
About the Authors
P. A. NikiforovRussian Federation
V. N. Lyapunova
Russian Federation
V. L. Osin
Russian Federation
A. Yu. Tarasova
Russian Federation
References
1. Никифоров П.А., Арутюнов А.Г., Бурков С.Г. и др. Успешный десятилетний опыт применения препарата Фортранс в клинической практике для подготовки к колоноскопии // Вестн. хир. гастроэнтерол. – 2008. – № 2. – С. 62–66.
2. Шапошников А.В., Дмитриева С.Ю., Горина И.И. Базовые принципы подготовки к фиброколоноскопии // Сonsilium medicum (Гастроэнтерология). – 2007. – № 2. – С. 57–62.
3. A consensus document on bowel preparation before colonoscopy: Prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) // Gastrointest. Endosc. – 2006. – Vol. 63, N 7. – P. 894–908.
4. Adams W.J., Meagher A.P., Lubowski D.Z. et al. Bisacodyl reduces the volume of PEG solution required for bowel preparation // Dis. Colon Rectum. – 1994. – N 27. – P. 229–233.
5. Afridi S.A., Barthel J.S., King P.D. et al. Prospective, randomized trial comparing a new sodium phosphatebisacodyl regimen with conventional PEG-ES lavage for outpatient colonoscopy preparation // Gastrointest. Endosc. – 1995. – N 41. – P. 485–489.
6. Beck D.E., Fabzio V.W., Jagleman D.G. Comparison of oral lavage methods or preoperative colon cleansing // Dis. Colon Rectum. – 1986. – N 29. – P. 699–703. 7. Brady C.E., DiPalma J.A., Beck D.E. Effect of bisacodyl on gut lavage cleansing for colonoscopy // Am. Clin. Res. – 1987. – N 19. – P. 34–38.
7. Church J.M. Effectiveness of polyethylene glycol ante-grade gut lavage bowel preparation for colonoscopy-timing is the key // Dis. Colon Rectum. – 1998. – N 41. – P. 1223–1225.
8. Chun-Chia Chen, Wai-Wah Ng, Full-Young Chang, Shou-Dong Lee. Magnesium citrate–bisacodyl regimen proves better than castor oil for colonoscopic preparation // J. Gastroenterol. Hepatol. – Vol. 14, N 12. – P. 1219–1222.
9. Di Palma J.A., Marshall J.B. Comparison of a new sulfate-free polyethylene glycol lavage solution versus a standard solution for colonoscopy cleansing // Gastrointest. Endosc. – 1990. – N 36. – P. 285–289.
10. DiPalma J.A. Clinical trial: an efficacy evaluation of reduced bisacodyl given as part of a polyethylene glycol electrolyte solution preparation prior to colonoscopy // Aliment. Pharmacol. Ther. – 2007. – Vol. 26, N 8. – P. 1113–1119.
11. Ell C., Fischbach W., Keller R. et al. A randomized, blinded, prospective trial to compare the safety and efficacy of three bowel-cleansing solutions for colonoscopy (HSG-01*) // Endoscopy. – 2003. – N 35. – P. 300– 304.
12. Franke A., Hummel F., Knebel P. et al. Prospective evaluation of small bowel preparation with bisacodyl and sodium phosphate for capsule endoscopy // World J. Gastroenterol. – 2008. – Vol. 14, N 13. – P. 2061– 2064.
13. Kang M.J., Jung S.A., Jung J.M. et al. A Prospective trial comparing 4 L-polyethylene glycol with 2 L-polyethylene glycol plus bisacodyl tablets for colon preparation Korean // J. Gastrointest. Endosc. – 2008. – Vol. 37, N 3. – P. 167–173.
14. Ker T.S. Comparison of reduced volume versus four-liter electrolyte lavage solutions for colon cleansing // Am. Surg. – 2006. – N 72. – P. 909–911.
15. Lever E.L., Walter M.H., Condon S.C. et al. Addition of enemas to oral lavage preparation for colonoscopy is not necessary // Gastrointest Endosc. – 1992. – N 38. – P. 369–372.
16. Ray J.F., Souquet J.C. Acceptability of the colonic preparation. The interest in fractioning Fortrans doses for a better preparation to colonoscopy // Med. Chir. Dig. – 1990. – Vol. 19, N 8. – P. 507–511.
17. Rings E.H., Mulder C.J., Tytgat G.N. The effect of bisacodyl on whole-gut irrigation in preparation for colonoscopy // Endoscopy. – 1989. – N 21. – P. 172–173.
18. Schiller L.R. Clinical pharmacology and use of laxatives and lavage solutions // J. Clin. Gastroenterol. – 1988. – N 28. – P. 11–18.
19. Sharma V.K., Chockalingham S.K., Ugheoke E.A. et al. Prospective, randomized, controlled comparison of the use of polyethylene glycol electrolyte lavage solution in four-liter versus two-liter volumes and pretreatment with either magnesium citrate or bisacodyl for colonoscopy preparation // Gastrointest. Endosc. – 1998. – N 47. – P. 167–171.
20. Sowerbutts J.G. Use of bisacodyl in preparation of the bowels for a barium enema // Gut. – 1960. – N 1. – P. 175–178.
21. Zmora O., Wexner S.D. Bowel preparation for colonoscopy // Clin. Colon. Rectal. Surg. – 2001. – N 14. – P. 309–315.
22. Ziegenhagen D.J., Zehnter E., Tacke W. et al. Senna versus bisacodyl in addition to GoLytely lavage for colonoscopy preparation: A prospective randomized trial // Z. Gastroenterol. – 1992. – N 30. – P. 17–19.
Review
For citations:
Nikiforov P.A., Lyapunova V.N., Osin V.L., Tarasova A.Yu. Optimization of preparation for colonoscopy by application of the enteral form of dulcolax. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2010;20(1):88-91. (In Russ.)