Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Care Physicians)
https://doi.org/10.22416/1382-4376-2019-29-5-53-74
Abstract
Aim. The present guidelines intended for primary care physicians are aimed at facilitating early diagnosis of malignant tumours of the digestive system, which can significantly improve the immediate and long-term results of their treatment.
General provisions. The guidelines comprise sections devoted to esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gall bladder cancer, as well as pancreatic cancer. Each section contains information on risk factors and precancerous diseases, which allows a physician to identify whether a particular patient falls into the risk group of digestive system neoplasms. It is shown how digestive system cancers can be suspected on the basis of patients’ complaints and past medical history, as well as data obtained both from a direct examination and laboratory instrumental studies. Each section offers practical algorithms in cases of suspected esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gallbladder cancer, as well as pancreatic cancer.
Conclusion. The knowledge of clinical manifestations and risk factors in the development of digestive system neoplasms allows a physician to suspect cancer and devise a timely and adequate diagnostic strategy, including laboratory and instrumental studies at specialised clinical centres.
About the Authors
V. T. IvashkinRussian Federation
Vladimir T. Ivashkin — Dr. Sci. (Med.), RAS Academician, Prof., Head of Department, Department of Propaedeutics of Internal Diseases, Principal gastroenterologist.
119991, Moscow, Pogodinskaya str., 1, building 1.
I. V. Mayev
Russian Federation
Igor V. Mayev — Dr. Si. (Med.), RAS Academician, Prof., Departmental Head, Department of Internal Diseases Propedeutics and Gastroenterology
127473, Moscow, Delegatskaya str., 20, building 1.
A. D. Kaprin
Russian Federation
Andrey D. Kaprin — Dr. Si. (Med.), RAS Academician, General Director
249031, Obninsk, Marshala Zhukova str., 10.
M. Yu. Agapov
Russian Federation
Mikhail Yu. Agapov — Dr. Si. (Med.), Endoscopy doctor
198255, St. Petersburg, Prospect Veteranov, 56.
D. N. Andreev
Russian Federation
Dmitry N. Andreyev — Assist. Prof., Department of Internal Diseases Propedeutics and Gastroenterology
127473, Moscow, Delegatskaya Str., 20, building 1.
A. S. Vodoleev
Russian Federation
Alexander S. Vodoleev — Cand. Sci. (Med.), Departmental Head, Endoscopy Department
125284, Moscow, 2nd Botkinsky pr., 3.
M. Yu. Zharkova
Russian Federation
Maria S. Zharkova — Cand. Sci. (Med.), Departmental Head, Hepatology Department, V.H. Vasilenko Clinic of Internal Diseases Propaedeutics, Gastroenterology and Hepatology
119991, Moscow, Pogodinskaya str., 1, building 1.
M. P. Korolev
Russian Federation
Mikhail P. Korolev — Dr. Sci. (Med.), Departmental Head, Department of General Surgery with Endoscopy Course
191014, St. Petersburg, Liteyny prospect, 56.
Yu. A. Kucheryavyi
Russian Federation
Yury A. Kucheryavyi — Cand. Sci. (Med.), Assoc. Prof., Department of Internal Diseases and Gastroenterology Propedeutics; Researcher, Laboratory of Functional Research Methods in Gastroenterology.
127473, Moscow, Delegatskaya str., 20, building 1.
T. L. Lapina
Russian Federation
Tatiana L. Lapina — Cand. Sci. (Med.), associate professor, Department of Internal Diseases Propedeutics
19991, Moscow, Pogodinskaya str., 1, building 1.
M. V. Mayevskaya
Russian Federation
Marina V. Mayevskaya — Dr. Sci. (Med.), Professor, Department of Propaedeutics of Internal Diseases
119991, Moscow, Pogodinskaya str., 1, building 1.
A. V. Okhlobystin
Russian Federation
Aleksey V. Okhlobystin — Cand. Sci. (Med.), Assoc. Prof., Internal Diseases Propedeutics Department
119435, Moscow, Pogodinskaya str., 1, building 1.
Ch. S. Pavlov
Russian Federation
Chavdar S. Pavlov — Departmental Head, Therapeutic Department, Institute of Vocational Education and Training
252844, Moscow, 2nd Botkinsky pr., 5.
A. V. Paraskevova
Russian Federation
Anna V. Paraskevova — Physician, Department of Functional Diagnostics, V.H. Vasilenko Clinic of Internal Diseases Propaedeutics, Gastroenterology and Hepatology
119435, Moscow, Pogodinskaya str., 1, building 1.
S. S. Pirogov
Russian Federation
Sergey S. Pirogov — Dr. Sci. (Med.), Departmental Head, Endoscopy Department
125284, Moscow, 2nd Botkinsky pr., 3.
E. A. Poluektova
Russian Federation
Elena A. Poluektova — Dr. Sci. (Med.), Prof.
19991, Moscow, Pogodinskaya str., 1, building 1.
D. E. Rumyantseva
Russian Federation
Diana V. Rumyantseva — Physician, Gastroenterology Department, V.H. Vasilenko Clinic of Internal Diseases Propaedeutics, Gastroenterology and Hepatology
119435, Moscow, Pogodinskaya str., 1, building 1.
A. S. Trukhmanov
Russian Federation
Alexander S. Trukhmanov — Dr. Sci. (Med.), Prof., Internal Diseases Propedeutics Department
19991, Moscow, Pogodinskaya str., 1, building 1.
P. V. Tsarkov
Russian Federation
Petr V. Tsarkov — Dr. Sci. (Med.), Director, Clinic of Coloproctology and Minimally Invasive Surgery, University Clinical Hospital No.2
119991, Moscow, Pogodinskaya str. 1, building 1.
A. A. Sheptulin
Russian Federation
Arkady A. Sheptulin* — Dr. Sci. (Med.), Prof., Department of Internal Diseases Propedeutics, Medical faculty
119991, Moscow, Pogodinskaya str. 1, building 1.
O. S. Shifrin
Russian Federation
Oleg S. Shifrin — Dr. Sci. (Med.), Prof., Propaedeutics of Internal Diseases Department, Departmental Head, Department of Chronic Diseases of the Intestines and Pancreas, V.H. Vasilenko Clinic of the Propaedeutics of Internal Diseases, Gastroenterology and Gepatology
19991, Moscow, Pogodinskaya str., 1, building 1.
Review
For citations:
Ivashkin V.T., Mayev I.V., Kaprin A.D., Agapov M.Yu., Andreev D.N., Vodoleev A.S., Zharkova M.Yu., Korolev M.P., Kucheryavyi Yu.A., Lapina T.L., Mayevskaya M.V., Okhlobystin A.V., Pavlov Ch.S., Paraskevova A.V., Pirogov S.S., Poluektova E.A., Rumyantseva D.E., Trukhmanov A.S., Tsarkov P.V., Sheptulin A.A., Shifrin O.S. Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Care Physicians). Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2019;29(5):53-74. (In Russ.) https://doi.org/10.22416/1382-4376-2019-29-5-53-74