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Russian Journal of Gastroenterology, Hepatology, Coloproctology

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Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Care Physicians)

https://doi.org/10.22416/1382-4376-2019-29-5-53-74

Abstract

Aim. The present guidelines intended for primary care physicians are aimed at facilitating early diagnosis of malignant tumours of the digestive system, which can significantly improve the immediate and long-term results of their treatment.

General provisions. The guidelines comprise sections devoted to esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gall bladder cancer, as well as pancreatic cancer. Each section contains information on risk factors and precancerous diseases, which allows a physician to identify whether a particular patient falls into the risk group of digestive system neoplasms. It is shown how digestive system cancers can be suspected on the basis of patients’ complaints and past medical history, as well as data obtained both from a direct examination and laboratory instrumental studies. Each section offers practical algorithms in cases of suspected esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gallbladder cancer, as well as pancreatic cancer.

Conclusion. The knowledge of clinical manifestations and risk factors in the development of digestive system neoplasms allows a physician to suspect cancer and devise a timely and adequate diagnostic strategy, including laboratory and instrumental studies at specialised clinical centres.

About the Authors

V. T. Ivashkin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Vladimir T. Ivashkin — Dr. Sci. (Med.), RAS Academician, Prof., Head of Department, Department of Propaedeutics of Internal Diseases, Principal gastroenterologist.

119991, Moscow, Pogodinskaya str., 1, building 1.



I. V. Mayev
A.I. Yevdokimov Moscow State University of Medicine
Russian Federation

Igor V. Mayev — Dr. Si. (Med.), RAS Academician, Prof., Departmental Head, Department of Internal Diseases Propedeutics and Gastroenterology

127473, Moscow, Delegatskaya str., 20, building 1.



A. D. Kaprin
National Medical Research Radiological Center
Russian Federation

Andrey D. Kaprin — Dr. Si. (Med.), RAS Academician, General Director

249031, Obninsk, Marshala Zhukova str., 10.



M. Yu. Agapov
Saint Petersburg City Oncology Clinic
Russian Federation

Mikhail Yu. Agapov — Dr. Si. (Med.), Endoscopy doctor

198255, St. Petersburg, Prospect Veteranov, 56.



D. N. Andreev
A.I. Yevdokimov Moscow State University of Medicine
Russian Federation

Dmitry N. Andreyev — Assist. Prof., Department of Internal Diseases Propedeutics and Gastroenterology

127473, Moscow, Delegatskaya Str., 20, building 1.



A. S. Vodoleev
P.A. Hertsen Moscow Oncology Research Center — branch of “National Medical Research Radiological Center”
Russian Federation

Alexander S. Vodoleev — Cand. Sci. (Med.), Departmental Head, Endoscopy Department

125284, Moscow, 2nd Botkinsky pr., 3.



M. Yu. Zharkova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Maria S. Zharkova — Cand. Sci. (Med.), Departmental Head, Hepatology Department, V.H. Vasilenko Clinic of Internal Diseases Propaedeutics, Gastroenterology and Hepatology

119991, Moscow, Pogodinskaya str., 1, building 1.



M. P. Korolev
Saint Petersburg State Pediatric Medical University
Russian Federation

Mikhail P. Korolev — Dr. Sci. (Med.), Departmental Head, Department of General Surgery with Endoscopy Course

191014, St. Petersburg, Liteyny prospect, 56.



Yu. A. Kucheryavyi
A.I. Yevdokimov Moscow State University of Medicine
Russian Federation

Yury A. Kucheryavyi — Cand. Sci. (Med.), Assoc. Prof., Department of Internal Diseases and Gastroenterology Propedeutics; Researcher, Laboratory of Functional Research Methods in Gastroenterology.

127473, Moscow, Delegatskaya str., 20, building 1.



T. L. Lapina
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Tatiana L. Lapina — Cand. Sci. (Med.), associate professor, Department of Internal Diseases Propedeutics

19991, Moscow, Pogodinskaya str., 1, building 1.



M. V. Mayevskaya
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Marina V. Mayevskaya — Dr. Sci. (Med.), Professor, Department of Propaedeutics of Internal Diseases

119991, Moscow, Pogodinskaya str., 1, building 1.



A. V. Okhlobystin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Aleksey V. Okhlobystin — Cand. Sci. (Med.), Assoc. Prof., Internal Diseases Propedeutics Department

119435, Moscow, Pogodinskaya str., 1, building 1.



Ch. S. Pavlov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Chavdar S. Pavlov — Departmental Head, Therapeutic Department, Institute of Vocational Education and Training

252844, Moscow, 2nd Botkinsky pr., 5.



A. V. Paraskevova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Anna V. Paraskevova — Physician, Department of Functional Diagnostics, V.H. Vasilenko Clinic of Internal Diseases Propaedeutics, Gastroenterology and Hepatology

119435, Moscow, Pogodinskaya str., 1, building 1.



S. S. Pirogov
P.A. Hertsen Moscow Oncology Research Center — branch of “National Medical Research Radiological Center”
Russian Federation

Sergey S. Pirogov — Dr. Sci. (Med.), Departmental Head, Endoscopy Department

125284, Moscow, 2nd Botkinsky pr., 3.



E. A. Poluektova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Elena A. Poluektova — Dr. Sci. (Med.), Prof.

19991, Moscow, Pogodinskaya str., 1, building 1.



D. E. Rumyantseva
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Diana V. Rumyantseva — Physician, Gastroenterology Department, V.H. Vasilenko Clinic of Internal Diseases Propaedeutics, Gastroenterology and Hepatology

119435, Moscow, Pogodinskaya str., 1, building 1.



A. S. Trukhmanov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Alexander S. Trukhmanov — Dr. Sci. (Med.), Prof., Internal Diseases Propedeutics Department

19991, Moscow, Pogodinskaya str., 1, building 1.



P. V. Tsarkov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Petr V. Tsarkov — Dr. Sci. (Med.), Director, Clinic of Coloproctology and Minimally Invasive Surgery, University Clinical Hospital No.2

119991, Moscow, Pogodinskaya str. 1, building 1.



A. A. Sheptulin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Arkady A. Sheptulin* — Dr. Sci. (Med.), Prof., Department of Internal Diseases Propedeutics, Medical faculty

119991, Moscow, Pogodinskaya str. 1, building 1.



O. S. Shifrin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Oleg S. Shifrin — Dr. Sci. (Med.), Prof., Propaedeutics of Internal Diseases Department, Departmental Head, Department of Chronic Diseases of the Intestines and Pancreas, V.H. Vasilenko Clinic of the Propaedeutics of Internal Diseases, Gastroenterology and Gepatology

19991, Moscow, Pogodinskaya str., 1, building 1.



Review

For citations:


Ivashkin V.T., Mayev I.V., Kaprin A.D., Agapov M.Yu., Andreev D.N., Vodoleev A.S., Zharkova M.Yu., Korolev M.P., Kucheryavyi Yu.A., Lapina T.L., Mayevskaya M.V., Okhlobystin A.V., Pavlov Ch.S., Paraskevova A.V., Pirogov S.S., Poluektova E.A., Rumyantseva D.E., Trukhmanov A.S., Tsarkov P.V., Sheptulin A.A., Shifrin O.S. Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Care Physicians). Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2019;29(5):53-74. (In Russ.) https://doi.org/10.22416/1382-4376-2019-29-5-53-74

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ISSN 1382-4376 (Print)
ISSN 2658-6673 (Online)