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Russian Journal of Gastroenterology, Hepatology, Coloproctology

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Ischemic Changes in the Mucous Membrane of the Transverse Colon as a Complication of Acute Pancreatitis

https://doi.org/10.22416/1382-4376-2022-32-5-89-94

Abstract

Aim: to present a clinical case of a patient with a complicated course of acute pancreatitis.

Key points. A 31-year-old patient was admitted to the surgical department with a clinical picture of acute alcoholic pancreatitis. Signs of anemia were regarded as a consequence of gastrointestinal bleeding. Computed tomography with contrast enhancement, along with an increase in the size of the pancreas, the presence of foci of pancreatic necrosis with multiple fluid accumulations in the parapancreatic space, revealed smoothed gaustration and thickening of the walls of the predominantly transverse colon. During colonoscopy, ischemic changes of the colon mucosa were detected in a timely manner. Negative results of analysis for toxins A and B of Clostridioides difficile and pathogenic intestinal flora were obtained. By the means of intensive care, it was possible to achieve complete stabilization of the patient's condition, normalization of laboratory blood parameters and relief of ischemic processes in the colon wall.

Conclusion. Ischemic changes of the colon can serve as a complication of acute pancreatitis. A thorough analysis of the results of computed tomography at the first signs of colon lesion and colonoscopy contributed to the rapid detection of complications and prevention of irreversible colon ischemia.

About the Authors

D. A. Semenov
Medical Clinic “K + 31”
Russian Federation

Dmitrii A. Semenov — Cand. Sci. (Med.), Surgeon

119415, Moscow, Lobachevsky str., 42, bld. 4



S. G. Shapovalyants
Pirogov Russian National Research Medical University

Sergey G. Shapovalyants — Professor, Dr. Sci. (Med.), Honored Scientist of the Russian Fediration, Head of the surgery department

117997, Moscow,  Ostrovityanova str., 1



D. E. Seleznev
Medical Clinic “K + 31”; Pirogov Russian National Research Medical University

Denis E. Seleznev — M.D., Head of the Endoscopic Department, Endoscopist, Surgeon; Researcher

119415, Moscow, Lobachevsky str., 42, bld. 4



O. I. Yudin
Medical Clinic “K + 31”

Oleg I. Yudin — Cand. Sci. (Med.), Associate Medical Director

119415, Moscow, Lobachevsky str., 42, bld. 4



S. V. Korolev
Medical Clinic “K + 31”

Sergey V. Korolev — Cand. Sci. (Med.), Head of the surgery department

119415, Moscow, Lobachevsky str., 42, bld. 4



N. A. Gracheva
City Clinical Hospital No. 31 of the Moscow Healthcare Department

Natalia A. Gracheva — Cand. Sci. (Med.), Pathologist, Pathology Departament

119415, Moscow, Lobachevsky str., 42



L. M. Mikhaleva
City Clinical Hospital No. 31 of the Moscow Healthcare Department; Avtsyn Research Institute of Human Morphology of FSBI “Petrovsky National Research Centre of Surgery”

Liudmila M. Mikhaleva — Professor, Cand. Sci. (Med.), Head of the Laboratory of Clinical Morphology, Research Institute of Human Morphology; Head of the Pathology Department

119415, Moscow, Lobachevsky str., 42



K. S. Paramonenko
Medical Clinic “K + 31”

Konstantin S. Paramonenko — Anastesiologist

119415, Moscow, Lobachevsky str., 42, bld. 4



References

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Supplementary files

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For citations:


Semenov D.A., Shapovalyants S.G., Seleznev D.E., Yudin O.I., Korolev S.V., Gracheva N.A., Mikhaleva L.M., Paramonenko K.S. Ischemic Changes in the Mucous Membrane of the Transverse Colon as a Complication of Acute Pancreatitis. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2022;32(5):89-94. https://doi.org/10.22416/1382-4376-2022-32-5-89-94

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ISSN 1382-4376 (Print)
ISSN 2658-6673 (Online)